Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Peter, Pytel"'
Autor:
Zhichao Wu, Karen Dazelle, Zied Abdullaev, Hye-Jung Chung, Sonika Dahiya, Matthew Wood, Han Lee, Calixto-Hope G. Lucas, Qinwen Mao, Lorraina Robinson, Igor Fernandes, Matthew McCord, Peter Pytel, Kyle S. Conway, Rebecca Yoda, Jennifer M. Eschbacher, Ossama M. Maher, Martin Hasselblatt, Bret C. Mobley, Jack M. Raisanen, Kimmo J. Hatanpaa, Joshua Byers, Norman L. Lehman, Patrick J. Cimino, Drew Pratt, Martha Quezado, Kenneth Aldape
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-7 (2024)
Abstract Papillary tumor of the pineal region (PTPR) is an uncommon tumor of the pineal region with distinctive histopathologic and molecular characteristics. Experience is limited with respect to its molecular heterogeneity and clinical characterist
Externí odkaz:
https://doaj.org/article/ccb5b973f4b744df99cf76d1b717245c
Autor:
Atsuki En, Hanumakumar Bogireddi, Briana Thomas, Alexis V. Stutzman, Sachie Ikegami, Brigitte LaForest, Omar Almakki, Peter Pytel, Ivan P. Moskowitz, Kohta Ikegami
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114284- (2024)
Summary: Nuclear envelope (NE) ruptures are emerging observations in Lamin-related dilated cardiomyopathy, an adult-onset disease caused by loss-of-function mutations in Lamin A/C, a nuclear lamina component. Here, we test a prevailing hypothesis tha
Externí odkaz:
https://doaj.org/article/92b6c414548a4b3e8fe247bfe0d2b497
Publikováno v:
Interdisciplinary Neurosurgery, Vol 32, Iss , Pp 101754- (2023)
Symptoms, imaging features, and potential biopsy of intra-axial brain lesions are typically used to guide management and potentially render it more effective. Yet some cases exhibit atypical features that elude classification even in the light of his
Externí odkaz:
https://doaj.org/article/e6cc443639ec4124be75a08d825f81a6
Autor:
Pierre De Rossi, Virginie Buggia-Prévot, Benjamin L. L. Clayton, Jared B. Vasquez, Carson van Sanford, Robert J. Andrew, Ruben Lesnick, Alexandra Botté, Carole Deyts, Someya Salem, Eshaan Rao, Richard C. Rice, Angèle Parent, Satyabrata Kar, Brian Popko, Peter Pytel, Steven Estus, Gopal Thinakaran
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ddafc8cc4fce4f2296415a22e72b3b17
Autor:
Phillip McMullen, Peter Pytel, Alexis Snyder, Heather Smith, Jasmine Vickery, James Brainer, Robert Guzy, David Wu, Nathan Schoettler, Ayodeji Adegunsoye, Anne Sperling, John Hart, Lindsay Alpert, Anthony Chang, Sandeep Gurbuxani, Thomas Krausz, Aliya N Husain, Jeffrey Mueller
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 459-470 (2021)
Abstract Autopsies of patients who have died from COVID‐19 have been crucial in delineating patterns of injury associated with SARS‐CoV‐2 infection. Despite their utility, comprehensive autopsy studies are somewhat lacking relative to the globa
Externí odkaz:
https://doaj.org/article/57fc9257ef47416bbb35391229da3920
Autor:
Kathryn P. Scherpelz, Songlin Wang, Peter Pytel, Rama S. Madhurapantula, Atul K. Srivastava, Joseph R. Sachleben, Joseph Orgel, Yoshitaka Ishii, Stephen C. Meredith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease is characterized by neuritic plaques, the main protein components of which are β-amyloid (Aβ) peptides deposited as β-sheet-rich amyloid fibrils. Cerebral Amyloid Angiopathy (CAA) consists of cerebrovascular deposits
Externí odkaz:
https://doaj.org/article/549a89f7338448fd9a222cd6a6278088
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Several variants of the TANK-Binding Kinase 1 (TBK1) gene have been associated with frontotemporal dementia - amyotrophic lateral sclerosis (FTD-ALS) spectrum diseases. Corticobasal syndrome (CBS) is characterized by asymmetric limb rigidity, dystoni
Externí odkaz:
https://doaj.org/article/bba3de12f1d24ae9a20ea6bb2b091c3b
Autor:
Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Tumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies.
Externí odkaz:
https://doaj.org/article/b260b4d6e43c4d658b87dc58bb5c263c
Autor:
Melanie Meister-Broekema, Rebecca Freilich, Chandhuru Jagadeesan, Jennifer N. Rauch, Rocio Bengoechea, William W. Motley, E. F. Elsiena Kuiper, Melania Minoia, Gabriel V. Furtado, Maria A. W. H. van Waarde, Shawn J. Bird, Adriana Rebelo, Stephan Zuchner, Peter Pytel, Steven S. Scherer, Federica F. Morelli, Serena Carra, Conrad C. Weihl, Steven Bergink, Jason E. Gestwicki, Harm H. Kampinga
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
BAG3 is a Hsp70 co-chaperone that is highly expressed in muscles. Here the authors show that several myofibrillar myopathy causing BAG3 mutations are not impaired in Hsp70 binding, but rather impair the ADP-ATP exchange step of the Hsp70 cycle, causi
Externí odkaz:
https://doaj.org/article/ddf05b7beeda41dab42d91cc0f57bb70
Publikováno v:
Academic Pathology, Vol 7 (2020)
The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Pr
Externí odkaz:
https://doaj.org/article/f1e047121e2c4d418bd45dd023fe416f