Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Peter, Loskill"'
Autor:
Miriam Alb, Kristin Reiche, Michael Rade, Katherina Sewald, Peter Loskill, Madalena Cipriano, Tengku Ibrahim Maulana, Andries D. van der Meer, Huub J. Weener, Laure-Alix Clerbaux, Birgit Fogal, Nirav Patel, Karissa Adkins, Emma Lund, Ethan Perkins, Christopher Cooper, Jan van den Brulle, Hannah Morgan, Tina Rubic-Schneider, Hui Ling, Keith DiPetrillo, Jonathan Moggs, Ulrike Köhl, Michael Hudecek
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss sup1, Pp S13-S28 (2024)
The success of cellular immunotherapies such as chimeric antigen receptor (CAR) T cell therapy has led to their implementation as a revolutionary treatment option for cancer patients. However, the safe translation of such novel immunotherapies, from
Externí odkaz:
https://doaj.org/article/a47eb06e31b042a382f9b941094ae3ec
Autor:
Madalena Cipriano, Katharina Schlünder, Christopher Probst, Kirstin Linke, Martin Weiss, Mona Julia Fischer, Lena Mesch, Kevin Achberger, Stefan Liebau, Marina Mesquida, Valeria Nicolini, Anneliese Schneider, Anna Maria Giusti, Stefan Kustermann, Peter Loskill
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
To address the key physiological characteristics related to choroidal drug reactions and its immunology, Cipriano et al. developed a human immunocompetent choroidal in vitro model that mimics the tissue vascularization, pigmentation and immune respon
Externí odkaz:
https://doaj.org/article/947bc0fd7c1d4021ac050c034f4c9b24
Autor:
Julia Rogal, Julia Roosz, Claudia Teufel, Madalena Cipriano, Raylin Xu, Wiebke Eisler, Martin Weiss, Katja Schenke‐Layland, Peter Loskill
Publikováno v:
Advanced Science, Vol 9, Iss 18, Pp n/a-n/a (2022)
Abstract Obesity and associated diseases, such as diabetes, have reached epidemic proportions globally. In this era of “diabesity”, white adipose tissue (WAT) has become a target of high interest for therapeutic strategies. To gain insights into
Externí odkaz:
https://doaj.org/article/fd7ce4aaf78a48909e2c8abfed51e296
Autor:
Oliver Schneider, Alessia Moruzzi, Stefanie Fuchs, Alina Grobel, Henrike S. Schulze, Torsten Mayr, Peter Loskill
Publikováno v:
Materials Today Bio, Vol 15, Iss , Pp 100280- (2022)
Over the last decade, Organ-on-Chip (OoC) emerged as a promising technology for advanced in vitro models, recapitulating key physiological cues. OoC approaches tailored for cardiac tissue engineering resulted in a variety of platforms, some of which
Externí odkaz:
https://doaj.org/article/e998307047ab4334b290d1d5b4ea8313
Autor:
Ulgu Arslan, Alessia Moruzzi, Joanna Nowacka, Christine L. Mummery, Dominik Eckardt, Peter Loskill, Valeria V. Orlova
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100259- (2022)
Models of heart disease and drug responses are increasingly based on human pluripotent stem cells (hPSCs) since their ability to capture human heart (dys-)function is often better than animal models. Simple monolayer cultures of hPSC-derived cardiomy
Externí odkaz:
https://doaj.org/article/e02262e66da14e30b503ad44e201cc31
Autor:
Tanvi Shroff, Kehinde Aina, Christian Maass, Madalena Cipriano, Joeri Lambrecht, Frank Tacke, Alexander Mosig, Peter Loskill
Publikováno v:
Open Biology, Vol 12, Iss 3 (2022)
Non-clinical models to study metabolism including animal models and cell assays are often limited in terms of species translatability and predictability of human biology. This field urgently requires a push towards more physiologically accurate recap
Externí odkaz:
https://doaj.org/article/6021618bbcb940019884b6d998dd99de
Publikováno v:
Education Sciences, Vol 13, Iss 2, p 144 (2023)
Organ-on-chip (OoC) technology bridges the principles of biology and engineering to create a new generation of in vitro models and involves highly interdisciplinary collaboration across STEM disciplines. Training the next generation of scientists, te
Externí odkaz:
https://doaj.org/article/95061fbb281e4697b40e92159c411800
Publikováno v:
APL Bioengineering, Vol 4, Iss 4, Pp 046101-046101-11 (2020)
Organ-on-a-chip (OoC) systems have evolved to a promising alternative to animal testing and traditional cell assays in drug development and enable personalization for precision medicine. So far, most OoCs do not fully exploit the potential of microfl
Externí odkaz:
https://doaj.org/article/acb9e839e6084d089a95f140c6105c82
Autor:
Kevin Achberger, Christopher Probst, Jasmin Haderspeck, Sylvia Bolz, Julia Rogal, Johanna Chuchuy, Marina Nikolova, Virginia Cora, Lena Antkowiak, Wadood Haq, Nian Shen, Katja Schenke-Layland, Marius Ueffing, Stefan Liebau, Peter Loskill
Publikováno v:
eLife, Vol 8 (2019)
The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Additionally,
Externí odkaz:
https://doaj.org/article/0022f7a537914393be69e143a78fc034
Publikováno v:
ACS biomaterials scienceengineering. 8(11)
Over the past decade, organ-on-chip research has been one of the most prolific areas of the entire field of tissue engineering. The development of organ-on-chip models requires an integrated interdisciplinary approach merging technologies and concept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3441c8d0844cdb216b433332bb226d
https://pubmed.ncbi.nlm.nih.gov/35760397
https://pubmed.ncbi.nlm.nih.gov/35760397