Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Peter, Lassota"'
Autor:
Jae-Beom Kim, Konnie Urban, Edward Cochran, Steve Lee, Angel Ang, Bradley Rice, Adam Bata, Kenneth Campbell, Richard Coffee, Alex Gorodinsky, Zhan Lu, He Zhou, Takashi Kei Kishimoto, Peter Lassota
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9364 (2010)
Early detection of tumors can significantly improve the outcome of tumor treatment. One of the most frequently asked questions in cancer imaging is how many cells can be detected non-invasively in a live animal. Although many factors limit such detec
Externí odkaz:
https://doaj.org/article/aff5baf930c54d018af305b3ab814cfe
Publikováno v:
Anti-Cancer Drugs. 22:58-78
The aim was to determine the potential of the allosteric mammalian target of rapamycin inhibitor, everolimus, to act in combination with cytotoxic anticancer compounds in vitro and in vivo. A concomitant combination in vitro showed no evidence of ant
Autor:
Stacy W. Remiszewski, Lidia C. Sambucetti, Kenneth W. Bair, John Bontempo, David Cesarz, Nagarajan Chandramouli, Ru Chen, Min Cheung, Susan Cornell-Kennon, Karl Dean, George Diamantidis, Dennis France, Michael A. Green, Kobporn Lulu Howell, Rina Kashi, Paul Kwon, Peter Lassota, Mary S. Martin, Yin Mou, Lawrence B. Perez, Sushil Sharma, Troy Smith, Eric Sorensen, Francis Taplin, Nancy Trogani, Richard Versace, Heather Walker, Susan Weltchek-Engler, Alexander Wood, Arthur Wu, Peter Atadja
Publikováno v:
Journal of Medicinal Chemistry. 46:4609-4624
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC50s < 400 nM in a partially purified enzyme assay. However, potency in cell g
Autor:
Paul W. Ford, Kirk R. Gustafson, Tawnya C. McKee, Nobuharu Shigematsu, Laura K. Maurizi, Lewis K. Pannell, David E. Williams, E. Dilip de Silva, Peter Lassota, Theresa M. Allen, Rob Van Soest, Raymond J. Andersen, Michael R. Boyd
Publikováno v:
Journal of the American Chemical Society, 121, 5899-5909. American Chemical Society
The novel cyclic depsipeptides papuamides A (1), B (2), C (3), and D (4) have been isolated from Papua New Guinea collections of the sponges Theonella mirabilis and Theonella swinhoei. Their structures were determined by a combination of spectroscopi
Publikováno v:
The Journal of Organic Chemistry. 63:4838-4841
Publikováno v:
ChemInform. 29
Autor:
Edward Cochran, Alex Gorodinsky, Zhan Lu, Kenneth D. Campbell, Peter Lassota, Steve R. Lee, Jae-Beom Kim, He Zhou, Konnie Urban, Takashi Kishimoto, Bradley W. Rice, Angel Ang, Adam Bata, Richard Coffee
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9364 (2010)
PLoS ONE
PLoS ONE
Early detection of tumors can significantly improve the outcome of tumor treatment. One of the most frequently asked questions in cancer imaging is how many cells can be detected non-invasively in a live animal. Although many factors limit such detec
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(15)
Purpose: We have generated an EL1-luc/TAg transgenic mouse model that develops spontaneous and bioluminescent acinar cell carcinomas. We applied this model to noninvasively monitor tumor development and drug response. Experimental Design: EL1-luc/TAg
Autor:
Valerie S. Bernan, Peter Lassota, Jeffrey E. Janso, Guy T. Carter, Leonard A. McDonald, Laurel R. Barbieri
Publikováno v:
Journal of natural products. 67(9)
07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC(50) = 0.9 mi
Autor:
Peter Lassota
Publikováno v:
Biomedical Topical Meeting.