Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Peter, Langguth"'
Autor:
Sophie Luise Meiser, Jonas Pielenhofer, Ann-Kathrin Hartmann, Lara Stein, Jule Dettweiler, Stephan Grabbe, Markus P. Radsak, Peter Langguth
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Transcutaneous delivery systems bear several advantages over conventional needle-based injections. Considering the low bioavailability and poor water-solubility of imiquimod, a manufacturing process has been developed to incorporate imiquimod as susp
Externí odkaz:
https://doaj.org/article/84b0248e65984210829b7ef189071e4b
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 1, Pp 109-122 (2024)
Abstract Introduction The selection of inhaler device is of critical importance in chronic obstructive pulmonary disease (COPD) as the interaction between a patient’s inhalation profile and the aerosol characteristics of an inhaler can affect drug
Externí odkaz:
https://doaj.org/article/832681727c5c44aeb48ec95bd5e0d15e
Autor:
Melissa A. Graewert, Christoph Wilhelmy, Tijana Bacic, Jens Schumacher, Clement Blanchet, Florian Meier, Roland Drexel, Roland Welz, Bastian Kolb, Kim Bartels, Thomas Nawroth, Thorsten Klein, Dmitri Svergun, Peter Langguth, Heinrich Haas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract We present a generically applicable approach to determine an extensive set of size-dependent critical quality attributes inside nanoparticulate pharmaceutical products. By coupling asymmetrical-flow field-flow fractionation (AF4) measurement
Externí odkaz:
https://doaj.org/article/6cbcb21a01a44fe191b433cb76ef64fd
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f8b0c33b4f3c4a62a0d15ea12f4f381c
Autor:
Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth, Matthias Mack, Sabine Muth, Hans-Christian Probst, Hansjörg Schild, Markus Philipp Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various i
Externí odkaz:
https://doaj.org/article/b6b81cbb0f6c4c90b928a7619a5c1a38
Autor:
Ann-Kathrin Hartmann, Joschka Bartneck, Jonas Pielenhofer, Sophie Luise Meiser, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Hansjörg Schild, Sabine Muth, Hans Christian Probst, Peter Langguth, Stephan Grabbe, Markus P. Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTranscutaneous immunization (TCI) is a non-invasive vaccination method promoting strong cellular immune responses, crucial for the immunological rejection of cancer. Previously, we reported on the combined application of the TLR7 agonist
Externí odkaz:
https://doaj.org/article/45104fbc88c34ace9bbdff9da15c6608
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to
Externí odkaz:
https://doaj.org/article/7d6f5fd597ff43259826599506c19bbf
Autor:
Christoph Wilhelmy, Isabell Sofia Keil, Lukas Uebbing, Martin A. Schroer, Daniel Franke, Thomas Nawroth, Matthias Barz, Ugur Sahin, Heinrich Haas, Mustafa Diken, Peter Langguth
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2068 (2023)
Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure
Externí odkaz:
https://doaj.org/article/0661639078014c83ae3f7dc08cc22219
Autor:
Jonas Pielenhofer, Sophie Luise Meiser, Karsten Gogoll, Anna-Maria Ciciliani, Mark Denny, Michael Klak, Berenice M. Lang, Petra Staubach, Stephan Grabbe, Hansjörg Schild, Markus P. Radsak, Hilde Spahn-Langguth, Peter Langguth
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 514 (2023)
The present article exemplifies the application of the concept of quality by design (QbD) for the systematic development of a nanoparticulate imiquimod (IMQ) emulsion gel formulation as an investigational medicinal product (IMP) for evaluation in an
Externí odkaz:
https://doaj.org/article/21953749a5224c1b9daae569bac7ee79
Autor:
Naseem A. Charoo, Daud B. Abdallah, Daoud T. Ahmed, Bertil Abrahamsson, Rodrigo Cristofoletti, Peter Langguth, Mehul Mehta, Alan Parr, James E. Polli, Vinod P. Shah, Atsushi Kambayashi, Jennifer Dressman
Publikováno v:
Journal of Pharmaceutical Sciences. 112:893-903
Levocetirizine, a histamine H1-receptor antagonist, is prescribed to treat uncomplicated skin rashes associated with chronic idiopathic urticaria as well as the symptoms of both seasonal and continual allergic rhinitis. In this monograph, the practic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf52980323e716a861a24f5248b3bc8d
https://doi.org/10.1016/j.xphs.2022.12.021
https://doi.org/10.1016/j.xphs.2022.12.021