Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Peter, Kochunov"'
Autor:
Ling Qiu, Chuang Liang, Peter Kochunov, Kent E. Hutchison, Jing Sui, Rongtao Jiang, Dongmei Zhi, Victor M. Vergara, Xiao Yang, Daoqiang Zhang, Zening Fu, Juan R. Bustillo, Shile Qi, Vince D. Calhoun
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract People affected by psychotic, depressive and developmental disorders are at a higher risk for alcohol and tobacco use. However, the further associations between alcohol/tobacco use and symptoms/cognition in these disorders remain unexplored.
Externí odkaz:
https://doaj.org/article/dfe0e394291a40acbbf2fce699c65519
Autor:
Xingfeng Shao, Qinyang Shou, Kimberly Felix, Brandon Ojogho, Xuejuan Jiang, Brian T Gold, Megan M Herting, Eric L Goldwaser, Peter Kochunov, Elliot Hong, Ioannis Pappas, Meredith Braskie, Hosung Kim, Steven Cen, Kay Jann, Danny JJ Wang
Publikováno v:
eLife, Vol 13 (2024)
The blood-brain barrier (BBB) plays a pivotal role in protecting the central nervous system (CNS), and shielding it from potential harmful entities. A natural decline of BBB function with aging has been reported in both animal and human studies, whic
Externí odkaz:
https://doaj.org/article/eff6590eb931418b858736f42a11a24e
Publikováno v:
NeuroImage, Vol 299, Iss , Pp 120839- (2024)
Accurate diagnosis of mental disorders is expected to be achieved through the identification of reliable neuroimaging biomarkers with the help of cutting-edge feature selection techniques. However, existing feature selection methods often fall short
Externí odkaz:
https://doaj.org/article/ffe8ca6a45dd4b9788c7352f53cdc3e0
Autor:
Xiaoming Du, Fow-Sen Choa, Joshua Chiappelli, Heather Bruce, Mark Kvarta, Ann Summerfelt, Yizhou Ma, William T. Regenold, Kevin Walton, George F. Wittenberg, Stephanie Hare, Si Gao, Andrew van der Vaart, Zhiwei Zhao, Shuo Chen, Peter Kochunov, L. Elliot Hong
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 324-332 (2024)
The smoking rate is high in patients with schizophrenia. Brain stimulation targeting conventional brain circuits associated with nicotine addiction has also yielded mixed results. We aimed to identify alternative circuitries associated with nicotine
Externí odkaz:
https://doaj.org/article/19a62d0c0d86446e9e5578dccda7a876
Autor:
Yizhou Ma, Joshua Chiappelli, Mark D. Kvarta, Heather Bruce, Andrew van der Vaart, Eric L. Goldwaser, Xiaoming Du, Hemalatha Sampath, Samantha Lightner, Jane Endres, Akram Yusuf, Alexa Yuen, Samantha Narvaez, Danny Campos-Saravia, Peter Kochunov, L. Elliot Hong
Publikováno v:
Schizophrenia, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract We evaluated two models to link stressful life events (SLEs) with the psychopathology of schizophrenia spectrum disorders (SSD). We separated SLEs into independent (iSLEs, unlikely influenced by one’s behavior) and dependent (dSLEs, likely
Externí odkaz:
https://doaj.org/article/73e77d3ee4264ab1ac7459673a99692d
Autor:
Ying Xing, Theo G.M. van Erp, Godfrey D. Pearlson, Peter Kochunov, Vince D. Calhoun, Yuhui Du
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109319- (2024)
Summary: The integration of neuroimaging with artificial intelligence is crucial for advancing the diagnosis of mental disorders. However, challenges arise from incomplete matching between diagnostic labels and neuroimaging. Here, we propose a label-
Externí odkaz:
https://doaj.org/article/01db7353d48c458e80c32167193d5b23
Autor:
Cheng Tian, Zhenyao Ye, Rozalina G. McCoy, Yezhi Pan, Chuan Bi, Si Gao, Yizhou Ma, Mo Chen, Jiaao Yu, Tong Lu, L. Elliot Hong, Peter Kochunov, Tianzhou Ma, Shuo Chen, Song Liu
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
BackgroundPoor glycemic control with elevated levels of hemoglobin A1c (HbA1c) is associated with increased risk of cognitive impairment, with potentially varying effects between sexes. However, the causal impact of poor glycemic control on white mat
Externí odkaz:
https://doaj.org/article/cc547b1548e64017bbec797e74fac68b
Autor:
Arnim J. Gaebler, Nilüfer Fakour, Felix Stöhr, Jana Zweerings, Arezoo Taebi, Mariia Suslova, Juergen Dukart, Joerg F. Hipp, Bhim M. Adhikari, Peter Kochunov, Suresh D. Muthukumaraswamy, Anna Forsyth, Thomas Eggermann, Florian Kraft, Ingo Kurth, Michael Paulzen, Gerhard Gründer, Frank Schneider, Klaus Mathiak
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Both, pharmacological and genome-wide association studies suggest N-methyl-D-aspartate receptor (NMDAR) dysfunction and excitatory/inhibitory (E/I)-imbalance as a major pathophysiological mechanism of schizophrenia. The identification of sha
Externí odkaz:
https://doaj.org/article/2a27b92802e64b309b19055bac2f2fa8
Autor:
Xiaoming Du, Stephanie Hare, Ann Summerfelt, Bhim M. Adhikari, Laura Garcia, Wyatt Marshall, Peng Zan, Mark Kvarta, Eric Goldwaser, Heather Bruce, Si Gao, Hemalatha Sampath, Peter Kochunov, Jonathan Z. Simon, L. Elliot Hong
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Aberrant gamma frequency neural oscillations in schizophrenia have been well demonstrated using auditory steady-state responses (ASSR). However, the neural circuits underlying 40 Hz ASSR deficits in schizophrenia remain poorly understood. Si
Externí odkaz:
https://doaj.org/article/5af5ae085cfe4fa19d64a2635f262793
Autor:
Shile Qi, Jing Sui, Godfrey Pearlson, Juan Bustillo, Nora I. Perrone-Bizzozero, Peter Kochunov, Jessica A. Turner, Zening Fu, Wei Shao, Rongtao Jiang, Xiao Yang, Jingyu Liu, Yuhui Du, Jiayu Chen, Daoqiang Zhang, Vince D. Calhoun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Schizophrenia is highly heritable and characterized by widespread brain abnormalities. Here, the authors identify schizophrenia polygenic risk associated multimodal frontotemporal network that can serve as a transdiagnostic brain signature specific t
Externí odkaz:
https://doaj.org/article/bc4f3b45df89475dafe32bfc962cd694