Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter, Kinirons"'
Autor:
Peter Kinirons, Paul M. Ryan
Publikováno v:
BMJ Case Rep
We report a case of a patient who presented complaining of a 1-week history of progressive lower limb weakness and decreased sensation bilaterally suggestive of a peripheral neuropathy, with vague associated symptoms of fluctuating concentration. Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18511a88ed8ab54f347ff7511c3d9877
https://doi.org/10.1136/bcr-2021-242716
https://doi.org/10.1136/bcr-2021-242716
Autor:
Derek Bowie, Caroline Meloche, Patrick Cossette, Lionel Carmant, Patricia M.G.E. Brown, Hélène Lacasse, Peter Kinirons, Pamela Lachance-Touchette, Fiona Bedford, Line Lapointe, Anne Lortie
Publikováno v:
European Journal of Neuroscience. 34:237-249
Epilepsy is a heterogeneous neurological disease affecting approximately 50 million people worldwide. Genetic factors play an important role in both the onset and severity of the condition, with mutations in several ion-channel genes being implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0f50da151346b5462ce995feeb70fc5
https://doi.org/10.1111/j.1460-9568.2011.07767.x
https://doi.org/10.1111/j.1460-9568.2011.07767.x
Autor:
Costas Michaelides, Elizabeth A. Thiele, Dipti Manchharam, Peter Kinirons, Ronald L. Thibert, Michelle J. Shapiro, Tanya John
Publikováno v:
Epilepsy Research. 81:143-147
Summary Objective To evaluate the use and tolerability of intravenous (IV) levetiracetam (LEV) in a pediatric cohort under 14 years of age. Methods A retrospective analysis of the use of the IV formulation of LEV was performed for the first 9 months
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231b28ef479f5385c34510495b433cc9
https://doi.org/10.1016/j.eplepsyres.2008.05.004
https://doi.org/10.1016/j.eplepsyres.2008.05.004
Autor:
Colin P. Doherty, Peter Kinirons
Publikováno v:
European Journal of Emergency Medicine. 15:187-195
Status epilepticus (SE) is a common medical emergency. Two problems continue to militate against improved outcome in SE, namely, failure to recognize the wide spectrum of clinical presentation and failure to treat in an appropriately aggressive and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7b458a4491a55ba3e7b4d59a0ab5e8
https://doi.org/10.1097/mej.0b013e3282f5559b
https://doi.org/10.1097/mej.0b013e3282f5559b
Autor:
Sarah K. Tate, Reetta Kälviäinen, Nicholas W. Wood, Kevin Murphy, Anne Mari Kantanen, David A. Hosford, Kevin V. Shianna, Stephanie L. Chissoe, Bronwyn E. Grinton, Peter Kinirons, Nicole M. Walley, Tracey D. Graves, Alice Stanton, Chantal Depondt, Michael E. Weale, Massimo Pandolfo, Leslie J. Sheffield, Samuel F. Berkovic, Norman Delanty, Terence J. O'Brien, Curtis Gumbs, Sanjay M. Sisodiya, Michael G. Hanna, Dongliang Ge, James O. McNamara, Rinki Singh, John Lynch, David Goldstein, Kristl Claeys, Cassandra Szoeke, Colin P. Doherty, Gianpiero L. Cavalleri, Ingrid E. Scheffer, Josemir W. Sander, Rachel A. Gibson, John C. Mulley, Rodney A. Radtke, Kristen N. Linney, John S. Duncan, Kai Eriksson, Deirdre O'Rourke
Publikováno v:
The lancet neurology
Summary Background The Epilepsy Genetics (EPIGEN) Consortium was established to undertake genetic mapping analyses with augmented statistical power to detect variants that influence the development and treatment of common forms of epilepsy. Methods W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141d5291d1f484e37869e5db9f13c380
https://doi.org/10.1016/s1474-4422(07)70247-8
https://doi.org/10.1016/s1474-4422(07)70247-8
Autor:
Anne Gehrmann, Sanjay M. Sisodiya, Anuranjan Anand, Nicholas W. Wood, John Lynch, Norman Delanty, Samuel F. Berkovic, Peter Kinirons, Sonia Gandhi, Nicole Soranzo, Parthasarathy Satishchandra, Thomas Sander, David Goldstein, Colin P. Doherty, John C. Mulley, Ingrid E. Scheffer, Ashish Kapoor, Gianpiero L. Cavalleri, Armin Heils, Nicole M. Walley, Chantal Depondt
Publikováno v:
Epilepsia. 48:706-712
Purpose: Although complex idiopathic generalized epilepsies (IGEs) are recognized to have a significant genetic component, as yet there are no known common susceptibility variants. It has recently been suggested that variation in the BRD2 gene confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900f3e54f6b4f698f5724eafa39eeba7
https://doi.org/10.1111/j.1528-1167.2007.00977.x
https://doi.org/10.1111/j.1528-1167.2007.00977.x
Autor:
Pamela, Lachance-Touchette, Patricia, Brown, Caroline, Meloche, Peter, Kinirons, Line, Lapointe, Hélène, Lacasse, Anne, Lortie, Lionel, Carmant, Fiona, Bedford, Derek, Bowie, Patrick, Cossette
Publikováno v:
The European journal of neuroscience. 34(2)
Epilepsy is a heterogeneous neurological disease affecting approximately 50 million people worldwide. Genetic factors play an important role in both the onset and severity of the condition, with mutations in several ion-channel genes being implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06905a448663c01c8cd8460e4a64004a
https://pubmed.ncbi.nlm.nih.gov/21762463
https://pubmed.ncbi.nlm.nih.gov/21762463
Autor:
David Goldstein, Michael E. Weale, Kevin Murphy, Gianpiero L. Cavalleri, Nicholas W. Wood, Norman Delanty, John Lynch, Chantal Depondt, Sanjay M. Sisodiya, Deirdre O'Rourke, Peter Kinirons, Sarah K. Tate, Colin P. Doherty, Kevin V. Shianna, Josemir W. Sander
Publikováno v:
Epilepsy research. 83(1)
Levetiracetam (LEV), a newer antiepileptic drug (AED) useful for several epilepsy syndromes, binds to SV2A. Identifying genetic variants that influence response to LEV may allow more tailored use of LEV. Obvious candidate genes are SV2A, SV2B and SV2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69772209de0b5ed16d49db822ed14280
https://pubmed.ncbi.nlm.nih.gov/18977120
https://pubmed.ncbi.nlm.nih.gov/18977120
Autor:
Guy A. Rouleau, Cécile Cieuta-Walti, Charles Deacon, Michael Shevell, Josée Poirier, Lionel Carmant, Patrick Cossette, Richard Desbiens, Peter Kinirons, Marie-Pierre Dubé, Dominique J. Verlaan, Anne Lortie, Jean-François Clément
Publikováno v:
American journal of medical genetics. Part A. (5)
Idiopathic generalized epilepsy (IGE) has evidence of a strong genetic etiology. We conducted genomewide linkage analysis for genes responsible for familial IGE in French-Canadian pedigrees. Twenty families segregating autosomal dominant epilepsy wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afee3fa3028cef754b1f29c91db7eb9
https://pubmed.ncbi.nlm.nih.gov/18241056
https://pubmed.ncbi.nlm.nih.gov/18241056
Autor:
Pat Dicker, Norman Delanty, Gianpiero L. Cavalleri, Peter Kinirons, Amre Shahwan, Colin P. Doherty, Mary McCarthy, Kevin Murphy, David Goldstein, Clare Muckian
Publikováno v:
Epilepsy research. 73(2)
Controversy has surrounded the reported association of the single nucleotide polymorphism (SNP) C3435T of the ATP-binding cassette subfamily B member 1 (ABCB1, MDR1) gene, with refractory epilepsy. Here we examine this question by: (1) attempting to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ec5a5893254a10ac8cef05bdabbcc6
https://pubmed.ncbi.nlm.nih.gov/17125969
https://pubmed.ncbi.nlm.nih.gov/17125969