Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Peter, Heusler"'
Autor:
Cristina, Cosi, Jean-Claude, Martel, Agnès L, Auclair, Ginetta, Collo, Laura, Cavalleri, Peter, Heusler, Ludovic, Leriche, Florence, Gaudoux, Pierre, Sokoloff, Paul C, Moser, Silvia, Gatti-McArthur
Publikováno v:
European journal of pharmacology. 890
F17464 (N-(3-{4-[4-(8-Oxo-8H-[1,3]-dioxolo-[4,5-g]-chromen-7-yl)-butyl]-piperazin-1-yl}-phenyl)-methanesulfonamide, hydrochloride) is a new potential antipsychotic with a unique profile. The compound exhibits high affinity for the human dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b579498fc9f91e8cb99dd31e6d42ed6
https://pubmed.ncbi.nlm.nih.gov/33065094
https://pubmed.ncbi.nlm.nih.gov/33065094
Autor:
Ginetta Collo, Silvia Gatti-McArthur, Jean-Claude Martel, Laura Cavalleri, Peter Heusler, Florence Gaudoux, Ludovic Leriche, Pierre Sokoloff, Paul Moser, Agnès Auclair, Cristina Cosi
F17464 (N-(3-{4-[4-(8-Oxo-8H-[1,3]-dioxolo-[4,5-g]-chromen-7-yl)-butyl]-piperazin-1-yl}-phenyl)-methanesulfonamide, hydrochloride) is a new potential antipsychotic with a unique profile. The compound exhibits high affinity for the human dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e18da60ece16b164dcfcc48d13bf933
http://hdl.handle.net/11379/535724
http://hdl.handle.net/11379/535724
Autor:
Frédérique Lantoine-Adam, Didier Cussac, Eliete Bouskela, Peter Heusler, Isabelle Rauly-Lestienne, Fatima Z. G. A. Cyrino
Publikováno v:
Microvascular Research. 114:1-11
The objectives of this study were to evaluate, in vitro and in vivo, the contribution of muscarinic receptors to the effects of Ruscus extract. Ruscus extract was tested in competition binding experiments at recombinant human muscarinic receptors, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec433f33d49b7c535d8907391cdd7f4d
https://doi.org/10.1016/j.mvr.2017.05.005
https://doi.org/10.1016/j.mvr.2017.05.005
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 388:509-516
N-methyl-d-aspartate (NMDA) receptor channels are implicated in a wide range of physiological and pathophysiological processes, and a large number of pharmacological agents have been introduced that target the receptor via diverse mechanisms of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e52fbbc1e73e67cd622b49c81a1b48
https://doi.org/10.1007/s00210-015-1085-6
https://doi.org/10.1007/s00210-015-1085-6
Distinctive in vitro signal transduction profile of NLX-112, a potent and efficacious serotonin 5-HT
Autor:
Adrian, Newman-Tancredi, Jean-Claude, Martel, Cristina, Cosi, Peter, Heusler, Fabrice, Lestienne, Mark A, Varney, Didier, Cussac
Publikováno v:
The Journal of pharmacy and pharmacology. 69(9)
NLX-112 (befiradol, F13640) is a selective serotonin 5-HTNLX-112 was tested on G-protein activation, inhibition of adenylyl cyclase, ERK1/2 phosphorylation (pERK) and receptor internalization in recombinant cell lines. NLX-112 was also tested on G-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f2649657d3d45a73ad6b03574257bc5
https://pubmed.ncbi.nlm.nih.gov/28612503
https://pubmed.ncbi.nlm.nih.gov/28612503
Autor:
Isabelle Rauly-Lestienne, Didier Cussac, Peter Heusler, Frédéric Finana, Claudie Cathala, Sophie Bernois, Luc De Vries
Publikováno v:
Cellular Signalling. 24:1648-1657
μ-opioid receptors have been shown to form heterodimers with several G protein coupled receptors involved in pain regulation such as α(2A)-adrenergic and neurokinin 1 receptors. Because the 5-HT(1A) receptor is also involved in pain control, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a513be0ee09675930f3fb0004cebdb
https://doi.org/10.1016/j.cellsig.2012.04.010
https://doi.org/10.1016/j.cellsig.2012.04.010
Autor:
Peter Heusler, Gerd Boehmer
Publikováno v:
Brain Research. 1135:85-91
The contribution of platelet-activating factor (PAF) to the induction of neocortical LTP was examined in rat brain slices containing the primary somatosensory cortex (SI). Field potentials evoked by single pulse stimulation in cortical layer IV were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994c0c244060a572858a60cdaa3ad0fc
https://doi.org/10.1016/j.brainres.2006.12.016
https://doi.org/10.1016/j.brainres.2006.12.016
Publikováno v:
Neuropharmacology. 52:1106-1113
The D 2 dopaminergic receptor represents a major target of antipsychotic drugs. Using the coupling of the human D 2long (hD 2L ) receptor to G protein-coupled inward rectifier potassium (GIRK) channels in Xenopus laevis oocytes, we examined the activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888ecc2058739c69f9bfcc5fc137fac2
https://doi.org/10.1016/j.neuropharm.2006.11.008
https://doi.org/10.1016/j.neuropharm.2006.11.008
Publikováno v:
Journal of receptor and signal transduction research. 36(2)
The appearance of "bell"- (or "inverted U"-) shaped agonist concentration-response curves (CRCs) in in vitro pharmacological experiments is a frequently observed but poorly communicated phenomenon. In the context of G protein coupled receptor researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b611256d993f826ba3904bf428368e93
https://pubmed.ncbi.nlm.nih.gov/26466637
https://pubmed.ncbi.nlm.nih.gov/26466637