Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Peter, Hegemann"'
Autor:
Johannes Oppermann, Andrey Rozenberg, Thomaz Fabrin, Cristian González-Cabrera, Rafael Parker, Oded Béjà, Matthias Prigge, Peter Hegemann
Publikováno v:
eLife, Vol 12 (2024)
Channelrhodopsins (ChRs) are light-gated ion channels widely used to optically activate or silence selected electrogenic cells, such as individual brain neurons. Here, we describe identifying and characterizing a set of anion-conducting ChRs (ACRs) f
Externí odkaz:
https://doaj.org/article/c7725742369a4a0b8651f39a2aa7a48f
Autor:
Amelie C. F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Holger Dill, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans mus
Externí odkaz:
https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6
Autor:
Johannes Oppermann, Paul Fischer, Arita Silapetere, Bernhard Liepe, Silvia Rodriguez-Rozada, José Flores-Uribe, Enrico Schiewer, Anke Keidel, Johannes Vierock, Joel Kaufmann, Matthias Broser, Meike Luck, Franz Bartl, Peter Hildebrandt, J. Simon Wiegert, Oded Béjà, Peter Hegemann, Jonas Wietek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/768a4007f7834da395853386ee5bf11d
Autor:
Rodrigo G. Fernandez Lahore, Niccolò P. Pampaloni, Enrico Schiewer, M.-Marcel Heim, Linda Tillert, Johannes Vierock, Johannes Oppermann, Jakob Walther, Dietmar Schmitz, David Owald, Andrew J. R. Plested, Benjamin R. Rost, Peter Hegemann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7ffc3b49612949f889a3337c05c5f6d7
Autor:
Matthias Broser, Anika Spreen, Patrick E. Konold, Enrico Schiewer, Suliman Adam, Veniamin Borin, Igor Schapiro, Reinhard Seifert, John T. M. Kennis, Yinth Andrea Bernal Sierra, Peter Hegemann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/66437da637c848348ff049b21ce79cbc
Autor:
Rodrigo G. Fernandez Lahore, Niccolò P. Pampaloni, Enrico Schiewer, M.-Marcel Heim, Linda Tillert, Johannes Vierock, Johannes Oppermann, Jakob Walther, Dietmar Schmitz, David Owald, Andrew J. R. Plested, Benjamin R. Rost, Peter Hegemann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Channelrhodopsins are light-gated ion channels used to control excitability of designated cells in large networks with high spatiotemporal resolution. While ChRs selective for H+, Na+, K+ and anions have been discovered or engineered, Ca2+-s
Externí odkaz:
https://doaj.org/article/cf735418d7f9440b89d2e18fa465a71a
Autor:
Olga Baidukova, Johannes Oppermann, Simon Kelterborn, Rodrigo G. Fernandez Lahore, Dimitri Schumacher, Heide Evers, Yousef Yari Kamrani, Peter Hegemann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Channelrhodopsin photoreceptors are responsible for phototaxis in C. reinhardtii. Here, authors introduce point mutations in the channel which modify photocycle kinetics and ion selectivity, resulting in a deeper understanding of phototaxis in low li
Externí odkaz:
https://doaj.org/article/67b20480c417438fba9abe55cff32818
Autor:
Arita Silapetere, Songhwan Hwang, Yusaku Hontani, Rodrigo G. Fernandez Lahore, Jens Balke, Francisco Velazquez Escobar, Martijn Tros, Patrick E. Konold, Rainer Matis, Roberta Croce, Peter J. Walla, Peter Hildebrandt, Ulrike Alexiev, John T. M. Kennis, Han Sun, Tillmann Utesch, Peter Hegemann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The authors present an in-depth investigation of excited state dynamics and molecular mechanism of the voltage sensing in microbial rhodopsins. Using a combination of spectroscopic investigations and molecular dynamics simulations, the study proposes
Externí odkaz:
https://doaj.org/article/2a436882e40e4c79b7b00aa20fa1dce0
Autor:
Silvia Rodriguez-Rozada, Jonas Wietek, Federico Tenedini, Kathrin Sauter, Neena Dhiman, Peter Hegemann, Peter Soba, J. Simon Wiegert
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.
Externí odkaz:
https://doaj.org/article/22517d16d1e5465185854dba3c42e5e3
Autor:
Peter Hegemann, Hartmut Michel
Publikováno v:
Biophysics and Physicobiology, Vol 20 (2023)
Externí odkaz:
https://doaj.org/article/82f440f16f01415297e1b39f841f7467