Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Peter, Havel"'
Autor:
Suchit Chidurala, Richard McCuller, Milena Samora, Yu Huo, James Graham, Kimber Stanhope, Peter Havel, Audrey Stone, Michelle Harrison
Publikováno v:
Physiology. 38
Diabetic peripheral neuropathy (DPN) is a debilitating complication of type 2 diabetes (T2D) and is often diagnosed only after irreparable nerve damage has occurred. Mechanical allodynia, previously nonpainful stimuli that becomes painful, presents e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369ac5b35fb69d78c9fbf68403ece44e
https://doi.org/10.1152/physiol.2023.38.s1.5795291
https://doi.org/10.1152/physiol.2023.38.s1.5795291
Autor:
Milena Samora, Yu Huo, James Graham, Kimber Stanhope, Peter Havel, Michelle Harrison, Audrey Stone
Publikováno v:
Physiology. 38
It is well established that prostaglandins, a product of cyclooxygenase (COX) enzymes contribute to evoking the exercise pressor reflex. Previous studies suggest that COX expression is upregulated in the peripheral nerves of those with type 2 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0974e19e0cf4d742e3a536791fa6e1e6
https://doi.org/10.1152/physiol.2023.38.s1.5733232
https://doi.org/10.1152/physiol.2023.38.s1.5733232
Autor:
Allison Wanting Xu, Christopher B Kaelin, Gregory J Morton, Kayoko Ogimoto, Kimber Stanhope, James Graham, Denis G Baskin, Peter Havel, Michael W Schwartz, Gregory S Barsh
Publikováno v:
PLoS Biology, Vol 3, Iss 12, p e415 (2005)
Normal aging in humans and rodents is accompanied by a progressive increase in adiposity. To investigate the role of hypothalamic neuronal circuits in this process, we used a Cre-lox strategy to create mice with specific and progressive degeneration
Externí odkaz:
https://doaj.org/article/4114ec43dfc945be96b9873c0a23960f
Autor:
Peter Havel
Summary: Glutathione reductase (GR, EC 1.6.4.2) is a flavoprotein that catalyzes the NADPH- dependent reduction of oxidized glutathione (GSSG) to glutathione (GSH). This enzyme is essential for the GSH redox cycle which maintains adequate levels of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::894cc71aa4c525d392e70b2c1ecac772
https://doi.org/10.17504/protocols.io.68ehhte
https://doi.org/10.17504/protocols.io.68ehhte
Autor:
Peter Havel
Summary: Cayman Chemical's Protein Carbonyl Colorimetric Assay Kit is a convenient colorimetric assay for the measurement of oxidized proteins. Protein samples are derivatized by making use of the reaction between 2,4-dinitrophenylhydrazine (DNPH) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695c5b7d40ff614ee63e3bf0aea02af7
https://doi.org/10.17504/protocols.io.63hhgj6
https://doi.org/10.17504/protocols.io.63hhgj6
Autor:
Peter Havel
Summary: The lipid extraction method is based on work by Folch 1957. Tissue is homogenized and put into a 2:1 chloroform and methanol mix. The mix is separated into two phases by adding a salt solution. The upper phase contains any non-lipid substanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25273bd67075c5f1f3f90d14e4047457
https://doi.org/10.17504/protocols.io.62thgen
https://doi.org/10.17504/protocols.io.62thgen
Autor:
Peter Havel
Summary: Glucagon is a 29 amino acid polypeptide processed from proglucagon in pancreatic alpha cells. In intestinal L-cells proglucagon is cleaved into glicentin, corresponding to proglucagon residues no 1-69. Glicentin can further be processed into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853e257104f8cb4d2188991ecc63b729
https://doi.org/10.17504/protocols.io.63ihgke
https://doi.org/10.17504/protocols.io.63ihgke
Autor:
Peter Havel
Summary: Triglycerides are enzymatically hydrolyzed by lipase to free fatty acids and glycerol. The glycerol is phosphorylated by adenosine triphosphate (ATP) with glycerol kinase (GK) to produce glycerol-3- phosphate and adenosine diphosphate. Glyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e602430b0bc13a1c0d852d0bacafef58
https://doi.org/10.17504/protocols.io.yw3fxgn
https://doi.org/10.17504/protocols.io.yw3fxgn
Autor:
Peter Havel
Summary: The enzyme methodology employed in this reagent is based on the reaction first described by Talke and Schubert. To shorten and simplify the assay, the calculations are based on the discovery of Tiffany, et al. that urea concentration is prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa942f1340ec5260372b25a2ab4286ae
https://doi.org/10.17504/protocols.io.yw6fxhe
https://doi.org/10.17504/protocols.io.yw6fxhe
Autor:
Peter Havel
Summary: Albumin blue dye is a stain for the specific and sensitive spectrofluorometric determination of albumin in natural matrices. AB 580 binds to the albumin present in urine samples and the fluorescence can be quantified using a fluorimeter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e1b4f8e4c88bf5d4b9b8855d74dd95
https://doi.org/10.17504/protocols.io.yw5fxg6
https://doi.org/10.17504/protocols.io.yw5fxg6