Elevated Antibody Titers to Epstein–Barr Virus and Cytomegalovirus in Patients with Drug-Induced Lupus

Autor: Julie Knudsen, Nicole Hartwig Trier, Anette Holck Draborg, Christoffer Tandrup Nielsen, Søren Jacobsen, Peter Højrup, Gunnar Houen

Publikováno v: Viruses, Vol 15, Iss 4, p 986 (2023)

Systemic lupus erythematosus (SLE) is an autoimmune disease, which has been associated with Epstein–Barr virus (EBV) and Cytomegalovirus (CMV) infection. Drug-induced lupus (DIL) is a lupus-like disease caused by the intake of therapeutic drugs, wh

Externí odkaz: https://doaj.org/article/63dacebf094c48cb902c0709e50fc25b

Epitope Mapping of Monoclonal Antibodies to Calreticulin Reveals That Charged Amino Acids Are Essential for Antibody Binding

Autor: Ann Christina Bergmann, Cecilie Kyllesbech, Rimantas Slibinskas, Evaldas Ciplys, Peter Højrup, Nicole Hartwig Trier, Gunnar Houen

Publikováno v: Antibodies, Vol 10, Iss 3, p 31 (2021)

Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have s

Externí odkaz: https://doaj.org/article/9a5e3cfda283407eb990bb293e0057be

Immunoglobulin G structure and rheumatoid factor epitopes.

Autor: Sheila Lefoli Maibom-Thomsen, Nicole Hartwig Trier, Bettina Eide Holm, Kirsten Beth Hansen, Morten Ib Rasmussen, Anna Chailyan, Paolo Marcatili, Peter Højrup, Gunnar Houen

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0217624 (2019)

Antibodies are important for immunity and exist in several classes (IgM, IgD, IgA, IgG, IgE). They are composed of symmetric dimeric molecules with two antigen binding regions (Fab) and a constant part (Fc), usually depicted as Y-shaped molecules. Rh

Externí odkaz: https://doaj.org/article/8182c74571d94b359ea6c0e65d38cc51

Tyrosine-sulfated dermatopontin shares multiple binding sites and recognition determinants on triple-helical collagens with proteins implicated in cell adhesion and collagen folding, fibrillogenesis, cross-linking, and degradation

Autor: Morten M. Jensen, Arkadiusz Bonna, Sigurd J. Frederiksen, Samir W. Hamaia, Peter Højrup, Richard W. Farndale, Henrik Karring

Publikováno v: Jensen, M M, Bonna, A, Frederiksen, S J, Hamaia, S W, Højrup, P, Farndale, R W & Karring, H 2022, ' Tyrosine-sulfated dermatopontin shares multiple binding sites and recognition determinants on triple-helical collagens with proteins implicated in cell adhesion and collagen folding, fibrillogenesis, cross-linking, and degradation ', Biochimica et Biophysica Acta-Proteins and Proteomics, vol. 1870, no. 5, 140771 . https://doi.org/10.1016/j.bbapap.2022.140771

Dermatopontin (DPT), a small extracellular matrix protein that stimulates collagen fibrillogenesis, contains sulfotyrosine residues but neither its level of sulfation nor its binding sites on fibrillar collagens are known. Here, we discovered that DP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdcee101707763855041d8db654fefec
https://findresearcher.sdu.dk:8443/ws/files/201244228/Tyrosine_sulfated_dermatopontin_shares_...pdf

An institutional analysis of how the construction industry's complexity affects waste:an alternative response to future market demands for sustainability

Autor: Fredslund, Lasse, Søder, Peter Højrup, de Place Hansen, Ernst Jan, Koch, Christian

Publikováno v: Fredslund, L, Søder, P H, de Place Hansen, E J & Koch, C 2022, An institutional analysis of how the construction industry's complexity affects waste : an alternative response to future market demands for sustainability . in A Tutesigensi & C J Neilson (eds), Proceedings of the 38th Annual ARCOM Conference . Association of Researchers in Construction Management, Glasgow, UK, pp. 612-621, The Association of Researchers in Construction Management Annual Conference 2022 : ARCOM 2022, Glasgow, United Kingdom, 05/09/2022 . < http://www.arcom.ac.uk/-docs/proceedings/9bce04aca0c77752414e88656cad1115.pdf >

As a main consumer of resources and an important economic driver, supranational authorities (UN/EU) are expecting the construction industry to address sustainability issues, making the construction process an extremely complex activity. A response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::617342dfd93909b8f28180928639c838
https://vbn.aau.dk/da/publications/6d508547-f8f8-4906-8de5-982e4cb4e537