Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Peter, Geggier"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Single-molecule FRET (smFRET) is a powerful imaging platform capable of revealing dynamic changes in the conformation and proximity of biological molecules. The expansion of smFRET imaging into living cells creates both numerous new research opportun
Externí odkaz:
https://doaj.org/article/e79b0c9b51604bc2ad840e75fa536cfc
Autor:
Michael D. Holsey, Grant T. Gilmore, Adam W. Smith, Jonathan A. Javitch, Avik Kumar Pati, Kaleeckal G. Harikumar, Zhou Zhou, Jozsef Meszaros, Laurence J. Miller, Khuloud Jaqaman, Peter Geggier, Signe Mathiasen, Wesley B. Asher, Megan J. Kaliszewski, Mitchell D. McCauley, Scott C. Blanchard, Daniel S. Terry, Alekhya Govindaraju
Publikováno v:
Nature Methods. 18:397-405
Class C G protein-coupled receptors (GPCRs) are known to form stable homodimers or heterodimers critical for function, but the oligomeric status of class A and B receptors, which constitute >90% of all GPCRs, remains hotly debated. Single-molecule fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1d5af5024e5772f7bfbd0e90f26b66
https://doi.org/10.1038/s41592-021-01081-y
https://doi.org/10.1038/s41592-021-01081-y
Autor:
Wesley B, Asher, Peter, Geggier, Michael D, Holsey, Grant T, Gilmore, Avik K, Pati, Jozsef, Meszaros, Daniel S, Terry, Signe, Mathiasen, Megan J, Kaliszewski, Mitchell D, McCauley, Alekhya, Govindaraju, Zhou, Zhou, Kaleeckal G, Harikumar, Khuloud, Jaqaman, Laurence J, Miller, Adam W, Smith, Scott C, Blanchard, Jonathan A, Javitch
Publikováno v:
Nature methods. 18(4)
Class C G protein-coupled receptors (GPCRs) are known to form stable homodimers or heterodimers critical for function, but the oligomeric status of class A and B receptors, which constitute90% of all GPCRs, remains hotly debated. Single-molecule fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7f333d5b4d4c15d36b008483cec173d
https://pubmed.ncbi.nlm.nih.gov/33686302
https://pubmed.ncbi.nlm.nih.gov/33686302
Autor:
Wesley B. Asher, Steffen Jockusch, Hong Zhao, Zhou Zhou, Qinsi Zheng, Signe Mathiasen, Scott C. Blanchard, Peter Geggier, Roger B. Altman, Michael D. Holsey, Jonathan A. Javitch
Publikováno v:
Chemical Science. 8:755-762
Bright, long-lasting organic fluorophores enable a broad range of imaging applications. “Self-healing” fluorophores, in which intra-molecularly linked protective agents quench photo-induced reactive species, exhibit both enhanced photostability a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f13a4841343e6c492e7b59ceaddf4f8
https://doi.org/10.1039/c6sc02976k
https://doi.org/10.1039/c6sc02976k
Autor:
Daniel S. Terry, Yongfang Zhao, Peter Geggier, J. David Warren, Roger B. Altman, Zhou Zhou, Jonathan A. Javitch, Rachel A. Kolster, Scott C. Blanchard, Qinsi Zheng
Publikováno v:
Nature Methods. 9:68-71
Fluorescence applications requiring high photostability often depend on the use of solution additives to enhance fluorophore performance. Here we demonstrate that the direct or proximal conjugation of cyclooctatetraene (COT), 4-nitrobenzyl alcohol (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e635d05ecb4d667f922aa1961b61f5b
https://doi.org/10.1038/nmeth.1774
https://doi.org/10.1038/nmeth.1774
Autor:
Amanda Baker, Michael Lanagan, Clive Randall, Elena Semouchkina, George Semouchkin, Khalid Z. Rajab, Richard Eitel, Raj Mittra, Sorah Rhee, Peter Geggier, Claus Duschl, Gunter Fuhr
Publikováno v:
International Journal of Applied Ceramic Technology. 2:514-520
At the Keck Smart Materials Integration Laboratory at Penn State University, low-temperature co-fired ceramic (LTCC) material systems have been used to fabricate a number of devices for a variety of applications. This article presents an overview of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b260d5ebee6da0dced9e020d59fef1
https://doi.org/10.1111/j.1744-7402.2005.02052.x
https://doi.org/10.1111/j.1744-7402.2005.02052.x
Autor:
Daniel S. Terry, Scott C. Blanchard, James B. Munro, José N. Onuchic, Christian M. T. Spahn, Peter Geggier, Roger B. Altman, Paul C. Whitford, Kevin Y. Sanbonmatsu
Publikováno v:
Ribosomes ISBN: 9783709102145
Single-molecule fluorescence resonance energy transfer (smFRET) (reviewed in Munro et al., 2009) and cryo-electron microscopy (cryo-EM) investigations (Frank and Spahn, 2006; Spahn and Penczek, 2009; Fischer et al., 2010) of the translation apparatus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b168e2cb1cf9727aa2cb9f057cba26c
https://doi.org/10.1007/978-3-7091-0215-2_24
https://doi.org/10.1007/978-3-7091-0215-2_24
Autor:
Karissa Y. Sanbonmatsu, José N. Onuchic, Roger B. Altman, Scott C. Blanchard, Peter Geggier, Paul C. Whitford
Publikováno v:
RNA (New York, N.Y.). 16(6)
The ribosome is a massive ribonucleoprotein complex ( approximately 2.4 MDa) that utilizes large-scale structural fluctuations to produce unidirectional protein synthesis. Accommodation is a key conformational change during transfer RNA (tRNA) select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2703b15085fcc2b86a96bcea685836cf
https://pubmed.ncbi.nlm.nih.gov/20427512
https://pubmed.ncbi.nlm.nih.gov/20427512
Autor:
Roger B. Altman, James B. Munro, Richa Dave, Daniel S. Terry, Peter Geggier, Michael Feldman, Scott C. Blanchard
Aminoacyl-tRNA (aa-tRNA), in a ternary complex with elongation factor-Tu and GTP, enters the aminoacyl (A) site of the ribosome via a multi-step, mRNA codon-dependent mechanism. This process gives rise to the preferential selection of cognate aa-tRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e70f2747a0bf05cd6803e5d78f698c
https://europepmc.org/articles/PMC2917329/
https://europepmc.org/articles/PMC2917329/
Autor:
Roger B. Altman, Daniel S. Terry, James B. Munro, Michael Feldman, Peter Geggier, Richa Dave, Scott C. Blanchard
Publikováno v:
Wiley Encyclopedia of Chemical Biology
Imaging biological processes at the single-molecule scale enables the direct observation of the temporal and spatial dynamics of cellular processes. This relatively new branch of biophysical investigation, which was founded on a platform of physics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc48e06c09b1f4a0ea92ef4f82646e89
https://doi.org/10.1002/9780470048672.wecb540
https://doi.org/10.1002/9780470048672.wecb540