Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Peter, Filipcik"'
Publikováno v:
Cells, Vol 12, Iss 9, p 1235 (2023)
Rickettsial infections of the central nervous system (CNS) are manifested by severe neurological symptoms and represent a serious life-threatening condition. Despite the considerable health danger, only a few studies have been conducted focusing on t
Externí odkaz:
https://doaj.org/article/f60ca842d6af474bb41e358ff1a9cfb5
Autor:
Monika Zilkova, Anna Nolle, Branislav Kovacech, Eva Kontsekova, Petronela Weisova, Peter Filipcik, Rostislav Skrabana, Michal Prcina, Tomas Hromadka, Ondrej Cehlar, Gabriela Paulikova Rolkova, Denisa Maderova, Michal Novak, Norbert Zilka, Jeroen J. M. Hoozemans
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Immunotherapies targeting pathological tau have recently emerged as a promising approach for treatment of neurodegenerative disorders. We have previously showed that the mouse antibody DC8E8 discriminates between healthy and pathological tau
Externí odkaz:
https://doaj.org/article/a4c9386438824459a38b0c854273aacf
Autor:
Branislav Kovacech, Lubica Fialova, Peter Filipcik, Rostislav Skrabana, Monika Zilkova, Natalia Paulenka-Ivanovova, Andrej Kovac, Denisa Palova, Gabriela Paulikova Rolkova, Katarina Tomkova, Natalia Turic Csokova, Karina Markova, Michaela Skrabanova, Kristina Sinska, Neha Basheer, Petra Majerova, Jozef Hanes, Vojtech Parrak, Michal Prcina, Ondrej Cehlar, Martin Cente, Juraj Piestansky, Michal Fresser, Michal Novak, Monika Slavikova, Kristina Borsova, Viktoria Cabanova, Bronislava Brejova, Tomas Vinař, Jozef Nosek, Boris Klempa, Ludek Eyer, Vaclav Hönig, Martin Palus, Daniel Ruzek, Tereza Vyhlidalova, Petra Strakova, Blanka Mrazkova, Dagmar Zudova, Gizela Koubkova, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek, Norbert Zilka, Eva Kontsekova
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103818- (2022)
Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic
Externí odkaz:
https://doaj.org/article/d503988bb92a4f8ca2f39b041da95550
Autor:
Vladimira Durmanova, Zuzana Parnicka, Juraj Javor, Gabriel Minarik, Lubomir Vrazda, Barbora Vaseckova, Karin Gmitterova, Maria Kralova, Jan Pecenak, Peter Filipcik, Ivana Shawkatova
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Alzheimer’s disease (AD) is the most prevalent cause of dementia in elderly people worldwide. Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule
Externí odkaz:
https://doaj.org/article/d11a9d69bf074514b399d87d516e380c
Autor:
Martin Cente, Janka Perackova, Pavol Peracek, Marek Majdan, Igor Toth, Martin Mikulic, Jozef Hanes, Sara Porubska, Marian Spajdel, Barbora Kazickova, Igor Jurisica, Peter Filipcik
IMPORTANCEHead impacts resulting in traumatic brain injury (TBI) lead to elevation of phosphorylated tau protein in plasma, the biomarkers for patients with acute and chronic TBI. Dynamics of phosphorylated tau protein level (pTau) and ratio of pTau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca08ccfe612e93661626e0f18919556f
https://doi.org/10.1101/2022.10.13.22281039
https://doi.org/10.1101/2022.10.13.22281039
Publikováno v:
General physiology and biophysics. 40:523-539
Discovering novel diagnostic biomarkers and signatures for traumatic brain injury (TBI) represents a major challenge in the brain trauma research. Detailed analysis of post-concussive molecular pathways based on experimental data could provide a new
Autor:
Marek Majdan, Igor Tóth, Janka Peráčková, Silvio Parničan, Peter Filipcik, Martin Cente, Patrik Barila, Pavol Peráček
Publikováno v:
General physiology and biophysics. 40:569-576
Traumatic brain injury in contact sports can lead to serious health consequences either immediately or later in the life of injured subjects. The objective of this study was to estimate the incidence of head impacts in the Under 18 (U18) and Under 20
Autor:
Martin, Cente, Tomas, Smolek, Stefan, Zorad, Lubica, Fialova, Natalia, Paulenka Ivanovova, Katarina, Krskova, Lucia, Balazova, Rostislav, Skrabana, Peter, Filipcik
Publikováno v:
General physiology and biophysics. 40:577-584
Neurodegeneration is associated with hypertension and disturbance in fat metabolism. The complex interaction of neurodegenerative processes with both metabolic changes and blood pressure is still not fully elucidated. Here we demonstrate that the exp
Autor:
Peter Filipcik, Rostislav Skrabana
Publikováno v:
General physiology and biophysics. 40:435-438
Autor:
Lucia Balazova, Rostislav Skrabana, Peter Filipcik, Katarina Krskova, Tomas Smolek, Natalia Ivanovova, Lubica Fialova, Stefan Zorad, Martin Cente
Publikováno v:
Cellular and Molecular Neurobiology. 42:125-136
The close relationship between Alzheimer's disease (AD) and obesity was recognized many years ago. However, complete understanding of the pathological mechanisms underlying the interactions between degeneration of CNS and fat metabolism is still miss