Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Peter, F. Smith"'
Autor:
Peter F. Smith
There is now a practically universal consensus that our climate is changing rapidly, and as a direct result of human activities. While there is extensive debate about what we can do to mitigate the damage we are causing, it is becoming increasingly c
Autor:
Peter F Smith
Revised to incorporate and reflect changes and advances since it was first published the new edition of Architecture in a Climate of Change provides the latest basic principals of sustainability and the future of sustainable technology.Including new
Autor:
Peter F. Smith
Rounding off decades of exploration into the various ways in which buildings and urban sequences make an impact on the mind, The Dynamics of Delight emphasizes the qualitative aspects of form and space, providing designers with an analytical framewor
Autor:
Krishna Aluri, Scott Waldron, Karyn Schmidt, Maja M. Janas, Elena Castellanos-Rizaldos, Xiumin Liu, Michael Arciprete, Diane Ramsden, Jing Li, Vasant Jadhav, Robin McDougall, Christopher R. Brown, Bahru A. Habtemariam, Dale C. Guenther, Gabriel J. Robbie, Saket Agarwal, Muthiah Manoharan, Akshay Vaishnaw, Ivan Zlatev, Jeffrey Kurz, Jayaprakash K. Nair, Martin Maier, Saeho Chong, Sagar Agarwal, Christopher S. Theile, Steven Liou, Muthusamy Jayaraman, Varun Goel, Kevin Fitzgerald, Christopher MacLauchlin, Klaus Charisse, Joseph A Cichocki, Ju Liu, Yuanxin Xu, Peter F Smith, Jing-Tao Wu, Xuemei Zhang, Yongli Gu
Publikováno v:
Drug Metabolism and Disposition. 50:781-797
Conjugation of oligonucleotide therapeutics, including small interfering ribonucleic acids (siRNAs) or antisense oligonucleotides (ASOs) to N-acetylgalactosamine (GalNAc) ligands has become the primary strategy for hepatocyte-targeted delivery, and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa4ae67a6f9cc6256cba922321905899
https://doi.org/10.1124/dmd.121.000428
https://doi.org/10.1124/dmd.121.000428
Autor:
Li-Hua Guan, Qianfan Wang, Jing Li, Carrie Rocca, Valerie A. Clausen, Saeho Chong, Chris Tran, Yuanxin Xu, Guodong Zhang, Michael Arciprete, Ju Liu, Diana Najarian, Jing-Tao Wu, Xuemei Zhang, Peter F Smith
Publikováno v:
Drug Metabolism and Disposition. 49:572-580
Givosiran is an N-acetylgalactosamine-conjugated RNA interference therapeutic that targets 5'-aminolevulinate synthase 1 mRNA in the liver and is currently marketed for the treatment of acute hepatic porphyria. Herein, nonclinical pharmacokinetics an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845f7b4ca8072422f3e99326db273257
https://doi.org/10.1124/dmd.121.000381
https://doi.org/10.1124/dmd.121.000381
Autor:
Peter F Smith
Publikováno v:
New Journal of Physics, Vol 21, Iss 5, p 053022 (2019)
Sterile neutrinos in the keV mass range may constitute the galactic dark matter. Various proposed direct detection and laboratory searches are summarized. It is suggested that a promising method for searching for keV sterile neutrinos in the laborato
Externí odkaz:
https://doaj.org/article/41ef8a2dadce4726831b427ab223683a
Autor:
Krishna Aluri, Laura Sepp-Lorenzino, Christopher R. Brown, Kevin Fitzgerald, Akin Akinc, Martin Maier, Lauren Blair, Peter F Smith, Ju Liu, Jing Li, Ramesh Indrakanti, Biplab Das, Xiumin Liu, Ivan Zlatev, Scott A Barros, Kallanthottathil G. Rajeev, Yongfeng Jiang, Saket Agarwal, Akshay Vaishnaw, Chris Tran, Klaus Charisse, Jingxuan Liu, Muthiah Manoharan, Shigeo Matsuda, Jayaprakash K. Nair, Jessica E. Sutherland, Tracy Zimmermann, Yuanxin Xu, Jing-Tao Wu, Wendell P Davis, Xuemei Zhang, Maja M. Janas, Vasant Jadhav, Mark K Schlegel
Publikováno v:
Nucleic Acids Research
For oligonucleotide therapeutics, chemical modifications of the sugar-phosphate backbone are frequently used to confer drug-like properties. Because 2′-deoxy-2′-fluoro (2′-F) nucleotides are not known to occur naturally, their safety profile wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3324d6db543ac6effbceb9279407203c
https://doi.org/10.1093/nar/gkz140
https://doi.org/10.1093/nar/gkz140
Autor:
Peter F. Smith
La construcción de edificios está especialmente implicada en las emisiones de dióxido de carbono, y es conveniente que su diseño y construcción sea un factor primordial en la ofensiva por mitigar los efectos del cambio climático.En la nueva con
Autor:
Peter F. Smith, Lauree E. Gott
Publikováno v:
Maine Policy Review, Vol 17, Iss 1 (2008)
Externí odkaz:
https://doaj.org/article/1bf42509ef0d4039aa70b2d6d3d039ee
Autor:
Christian M. Leutenegger, Roberta J. Cahill, Melissa J. Beall, Genevieve Clark, Thomas P. O'connor, Peter F. Smith, Ramaswamy Chandrashekar, Jesse Buch, Brendon Thatcher
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 29:654-659
Feline leukemia virus (FeLV) is an oncogenic retrovirus of cats. Immunoassays for the p27 core protein of FeLV aid in the detection of FeLV infections. Commercial microtiter-plate ELISAs have rapid protocols and visual result interpretation, limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9928dc5c37b235f6d938eb44d6892d65
https://doi.org/10.1177/1040638717710451
https://doi.org/10.1177/1040638717710451