Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Peter, Dobelis"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41108 (2012)
Kynurenic acid (KYNA), a classical ionotropic glutamate receptor antagonist is also purported to block the α7-subtype nicotinic acetylcholine receptor (α7* nAChR). Although many published studies cite this potential effect, few have studied it dire
Externí odkaz:
https://doaj.org/article/c08ba3fb438b418e8199b4168191c011
Publikováno v:
British Journal of Pharmacology. 162:1351-1363
BACKGROUND AND PURPOSE Tobacco and alcohol are often co-abused producing interactive effects in the brain. Although nicotine enhances memory while ethanol impairs it, variable cognitive changes have been reported from concomitant use. This study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9835e880c42cbf56e32d3071aad86363
https://doi.org/10.1111/j.1476-5381.2010.01141.x
https://doi.org/10.1111/j.1476-5381.2010.01141.x
Autor:
Steven J. Coultrap, Michael Browning, Peter Dobelis, Jennifer L. Hellier, Jethro P. Jones, David R. Grosshans, Kevin J. Staley
Publikováno v:
Journal of Neurophysiology. 98:2818-2826
Metaplasticity describes the stabilization of synaptic strength such that strong synapses are likely to remain strong while weak synapses are likely to remain weak. A potential mechanism for metaplasticity is a correlated change in both N-methyl-d-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec789f6b1a218b5b3f3099d0e084dd0
https://doi.org/10.1152/jn.00346.2007
https://doi.org/10.1152/jn.00346.2007
Autor:
Donald Cooper, Michael Baratta, Shinya Nakamura, Peter Dobelis, Matthew Pomrenze, Samuel Dolzani
Publikováno v:
Nature Precedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0441d66360c53ae07867a56ede43229c
https://doi.org/10.1038/npre.2012.7102
https://doi.org/10.1038/npre.2012.7102
Publikováno v:
Nature Precedings
The tryptophan metabolite, kynurenic acid (KYNA), is classically known to be an antagonist of ionotropic glutamate receptors. Within the last decade several reports have been published suggesting that KYNA also blocks nicotinic acetylcholine receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______984::02bcb5310b80126eeaf683261a9ee030
http://precedings.nature.com/documents/6277/version/1
http://precedings.nature.com/documents/6277/version/1
Publikováno v:
Nature Precedings.
The tryptophan metabolite, kynurenic acid (KYNA), is classically known to be an antagonist of ionotropic glutamate receptors. Within the last decade several reports have been published suggesting that KYNA also blocks nicotinic acetylcholine receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5a67edeb3ded2e616fe06ad3e39f7b
https://doi.org/10.1038/npre.2011.6277.1
https://doi.org/10.1038/npre.2011.6277.1
Autor:
Kevin J. Staley, Peter Dobelis, Susan A. Masino, Bruno G. Frenguelli, Timothy Pearson, Chris G. Dulla
In addition to affecting respiration and vascular tone, deviations from normal CO(2) alter pH, consciousness, and seizure propensity. Outside the brainstem, however, the mechanisms by which CO(2) levels modify neuronal function are unknown. In the hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090a6c4223f1a12f75e1e5330dedfce1
https://europepmc.org/articles/PMC1924599/
https://europepmc.org/articles/PMC1924599/
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 306(3)
The pharmacology of nicotinic receptor-mediated seizures was investigated in C3H mice. Eleven nicotinic agonists and six antagonists were administered centrally (i.c.v.). Epibatidine and epiboxidine were the most potent agonists tested, whereas acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee37d0bce991883c78b5675cfa580bc
https://pubmed.ncbi.nlm.nih.gov/12829730
https://pubmed.ncbi.nlm.nih.gov/12829730
Autor:
Seth A. Balogh, Jerry A. Stitzel, Paul Whiteaker, Peter Dobelis, Michael J. Marks, Allan C. Collins
Publikováno v:
Molecular pharmacology. 62(2)
Nicotine-stimulated (86)Rb(+) efflux and [(3)H]cytisine binding, both of which seem to measure the nicotinic acetylcholine receptor, composed of alpha4 and beta2 subunits, were assessed in eight brain regions obtained from 14 inbred mouse strains. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69ba54073e7fb60449f6ba3ed2e0bab
https://pubmed.ncbi.nlm.nih.gov/12130686
https://pubmed.ncbi.nlm.nih.gov/12130686
Publikováno v:
Pharmacogenetics. 11(4)
In a recent study, we reported that a restriction fragment length polymorphism associated with the alpha4 nicotinic receptor gene (Chrna4) may play a role in regulating differential sensitivity of LS and SS mouse lines to the seizure-inducing effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8dc17f97806d6c8d4e87e0f0ff6f36
https://pubmed.ncbi.nlm.nih.gov/11434511
https://pubmed.ncbi.nlm.nih.gov/11434511