Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Peter, De Cruz"'
Publikováno v:
Intestinal Research, Vol 22, Iss 4, Pp 397-413 (2024)
Acute severe ulcerative colitis (ASUC) is a medical emergency that affects approximately 25% of patients with ulcerative colitis at some point in time in their lives. Outcomes of ASUC are highly variable. Approximately 30% of patients do not respond
Externí odkaz:
https://doaj.org/article/60db3406b1ec4ac0bb43703a600a339b
Autor:
Danny Con, Peter De Cruz
Publikováno v:
Intestinal Research, Vol 22, Iss 4, Pp 439-452 (2024)
Background/Aims Robust management algorithms are required to reduce the residual risk of colectomy in acute severe ulcerative colitis (ASUC) refractory to standard infliximab salvage therapy. The aim of this study was to evaluate the performance and
Externí odkaz:
https://doaj.org/article/eed3fe20a05940dd98e4b892556812e7
Autor:
Jonathan P Segal, Mayur Garg, Miles P Sparrow, Gareth J Walker, Ashish Srinivasan, Peter De Cruz, Desmond Chee, Alex Boussioutas, Robert V Bryant, Georgina Hold, Gregory T Moore, Susan J Connor, Robert D Little, Mark G Ward, Jo McKenzie, Patrick Hilley, Robert B Gilmore, Manjeet Sandhu, Daniel Saitta, Elizabeth Chow, Lena Thin, Kate Lynch, Jane Andrews, Yoon K An, Emily K Wright
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction A substantial proportion of patients with inflammatory bowel disease (IBD) on intravenous infliximab require dose intensification. Accessing additional intravenous infliximab is labour-intensive and expensive, depending on insurance and
Externí odkaz:
https://doaj.org/article/c6f1e2d43a834509bfe7e3af4a9f737f
Autor:
Sharon Tran, Juliani Juliani, Tiffany J. Harris, Marco Evangelista, Julian Ratcliffe, Sarah L. Ellis, David Baloyan, Camilla M. Reehorst, Rebecca Nightingale, Ian Y. Luk, Laura J. Jenkins, Sonia Ghilas, Marina H. Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C. Lee, Peter De Cruz, Kinga Duszyc, Paul A. Gleeson, Benjamin T. Kile, Lisa A. Mielke, Alpha S. Yap, John M. Mariadason, W. Douglas Fairlie, Erinna F. Lee
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Autophagy-related genes have been closely associated with intestinal homeostasis. BECLIN1 is a component of Class III phosphatidylinositol 3-kinase complexes that orchestrate autophagy initiation and endocytic trafficking. Here we show intes
Externí odkaz:
https://doaj.org/article/fc863b699bb647f5926120d1c9e15000
Publikováno v:
JGH Open, Vol 7, Iss 12, Pp 1012-1015 (2023)
Abstract Recent data, indicating that inflammatory bowel disease (IBD) may be a risk factor for future chronic kidney disease, highlight the need to study the safety and clinical effectiveness of advanced IBD therapies in patients with end stage rena
Externí odkaz:
https://doaj.org/article/854f3dd6b2274409b50caea80e26b2a0
Autor:
Amy L. Hamilton, Michael A. Kamm, Peter De Cruz, Emily K. Wright, Hai Feng, Josef Wagner, Joseph J. Y. Sung, Carl D. Kirkwood, Michael Inouye, Shu-Mei Teo
Publikováno v:
Gut Microbes, Vol 11, Iss 6, Pp 1713-1728 (2020)
Background Microbial factors are likely to be involved in the recurrence of Crohn’s disease (CD) after bowel resection. We investigated the luminal microbiota before and longitudinally after surgery, in relation to disease recurrence, using 16S met
Externí odkaz:
https://doaj.org/article/7d7e6ad7acfc4dcb9b2e52307e404810
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 15 (2022)
Introduction: Anti-tumor necrosis factor (TNF) dose intensification represents an effective method of overcoming secondary loss of response (LOR); however, a subset of patients may not respond (tertiary non-response), or fail to demonstrate durable r
Externí odkaz:
https://doaj.org/article/37ee4b245206488a8597b36532a10d47
Autor:
Johan Burisch, Mirabella Zhao, Selwyn Odes, Peter De Cruz, Severine Vermeire, Charles N Bernstein, Gilaad G Kaplan, Dana Duricova, Dan Greenberg, Hans O Melberg, Mamoru Watanabe, Hyeong Sik Ahn, Laura Targownik, Valérie E H Pittet, Vito Annese, KT Park, Konstantinos H Katsanos, Marte L Høivik, Zeljko Krznaric, María Chaparro, Edward V Loftus, Peter L Lakatos, Javier P Gisbert, Willem Bemelman, Bjorn Moum, Richard B Gearry, Michael D Kappelman, Ailsa Hart, Marieke J Pierik, Jane M Andrews, Siew C Ng, Renata D'Inca, Pia Munkholm
Publikováno v:
The Lancet Gastroenterology & Hepatology. 8:458-492
The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease and ulcerative colitis in both developed and newly industrialised coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f439bbec157cb3b05f668e94ca706f
https://doi.org/10.1016/s2468-1253(23)00003-1
https://doi.org/10.1016/s2468-1253(23)00003-1
Publikováno v:
Journal of Gastroenterology and Hepatology. 38:724-732
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd1b80d67292324fabb226bcdee83c6
https://doi.org/10.1111/jgh.16133
https://doi.org/10.1111/jgh.16133
Publikováno v:
Journal of Crohn's and Colitis. 16:1797-1807
Introduction Crohn’s disease recurs after intestinal resection. This study evaluated accuracy of a new blood test, the Endoscopic Healing Index [EHI], in monitoring for disease recurrence. Methods Patients enrolled in the prospective POCER study [N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162e59a119f7b5eec620dec6915c1995
https://doi.org/10.1093/ecco-jcc/jjac076
https://doi.org/10.1093/ecco-jcc/jjac076