Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Peter, Czermak"'
Autor:
Oliver Birrenbach, Peter Czermak
Publikováno v:
Electronic Journal of Biotechnology, Vol 73, Iss , Pp 32-37 (2025)
Background: The efficiency of recombinant protein production in Yarrowia lipolytica is strongly influenced by the culture medium. Complex media have limited applications because the composition is undefined and variable, whereas chemically defined me
Externí odkaz:
https://doaj.org/article/70c81059f99d45f9b79bb86aa9527773
Autor:
Jan Barekzai, Jonas Friedrich, Maduwuike Okpara, Laura Refflinghaus, Dustin Eckhardt, Peter Czermak, Denise Salzig
Publikováno v:
AIMS Bioengineering, Vol 10, Iss 3, Pp 240-264 (2023)
Mesenchymal stem/stromal cell-derived extracellular vesicles (MSC-EVs) are considered a promising therapeutic tool in cell therapy due to their immunomodulatory, regenerative and angiogenic capabilities. However, there is a lack of process knowledge,
Externí odkaz:
https://doaj.org/article/bc8f83580e054c8b992062ede4f4d8bb
Autor:
Jan Thorbow, Andrea Strauch, Viktoria Pfening, Jan-Philip Klee, Patricia Brücher, Björn Boshof, Florian Petry, Peter Czermak, Maria Beatriz Herrera Sanchez, Denise Salzig
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 692 (2024)
The assessment of human liver stem cells (HLSCs) as cell therapeutics requires scalable, controlled expansion processes. We first focused on defining appropriate process parameters for HLSC expansion such as seeding density, use of antibiotics, optim
Externí odkaz:
https://doaj.org/article/e4203bea3ee140928a721baaf9c45d10
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 6, Iss , Pp 100355- (2023)
Replacement of fossil-based polymers is a current challenge, which needs a broad feedstock of bio-based substitutes produced with a reasonable CO2-footprint. As indigestible biopolymers ß-1,4-hemicelluloses were extracted with an extraction process
Externí odkaz:
https://doaj.org/article/afa449e659e6480680bbb3c6279ff2af
Publikováno v:
Electronic Journal of Biotechnology, Vol 56, Iss , Pp 75-83 (2022)
Background: Vibrio natriegens is a Gram-negative bacterium that offers a greater metabolic capacity than Escherichia coli for the production of recombinant proteins. This potential includes a low minimum doubling time of 7 min and a high maximum gluc
Externí odkaz:
https://doaj.org/article/32f61f89e0514dbaa81acc16fb0af194
Publikováno v:
Electronic Journal of Biotechnology, Vol 56, Iss , Pp 54-64 (2022)
Background: Spodoptera frugiperda (Sf-9) cells are often used to produce recombinant proteins by transient expression. The culture medium contributes to the efficiency of protein production, but the effect of modern insect cell culture media on Sf-9
Externí odkaz:
https://doaj.org/article/cf844e8eb94f4148892357eee5b07736
Autor:
Gregor Dekevic, Tobias Tertel, Lars Tasto, Deborah Schmidt, Bernd Giebel, Peter Czermak, Denise Salzig
Publikováno v:
Viruses, Vol 15, Iss 10, p 2013 (2023)
Yellow Fever (YF) is a severe disease that, while preventable through vaccination, lacks rapid intervention options for those already infected. There is an urgent need for passive immunization techniques using YF-virus-like particles (YF-VLPs). To ad
Externí odkaz:
https://doaj.org/article/601dcada36914762b028bbcbf0184c46
Autor:
Soraia R. Mendes, Ulrich Eckhard, Arturo Rodríguez-Banqueri, Tibisay Guevara, Peter Czermak, Enrique Marcos, Andreas Vilcinskas, F. Xavier Gomis-Rüth
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 534-544 (2022)
Aureolysin, a secreted metallopeptidase (MP) from the thermolysin family, functions as a major virulence factor in Staphylococcus aureus. No specific aureolysin inhibitors have yet been described, making this an important target for the development o
Externí odkaz:
https://doaj.org/article/1e0c32ae4f5848d6a20d93f2fff9494e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The antibiotic resistance crisis has prompted research into alternative candidates such as antimicrobial peptides (AMPs). However, the demand for such molecules can only be met by continuous production processes, which achieve high product y
Externí odkaz:
https://doaj.org/article/a195025d6e5948afbbdbbbfaad5ad88b
Autor:
Julie Harnischfeger, Mandy Beutler, Denise Salzig, Stefan Rahlfs, Katja Becker, Christoph G. Grevelding, Peter Czermak
Publikováno v:
Electronic Journal of Biotechnology, Vol 54, Iss , Pp 26-36 (2021)
Background: The heterologous expression of parasitic proteins is challenging because the sequence composition often differs significantly from host preferences. However, the production of such proteins is important because they are potential drug tar
Externí odkaz:
https://doaj.org/article/4fd2b672fc7b402d964cdd6bbfe5e85e