Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial

Autor: David S Lawrence, Charles Muthoga, David B Meya, Lillian Tugume, Darlisha Williams, Radha Rajasingham, David R Boulware, Henry C Mwandumba, Melanie Moyo, Eltas N Dziwani, Hendramoorthy Maheswaran, Cecilia Kanyama, Mina C Hosseinipour, Chimwemwe Chawinga, Graeme Meintjes, Charlotte Schutz, Kyla Comins, Funeka Bango, Conrad Muzoora, Samuel Jjunju, Edwin Nuwagira, Mosepele Mosepele, Tshepo Leeme, Chiratidzo E Ndhlovu, Admire Hlupeni, Shepherd Shamu, Timothée Boyer-Chammard, Síle F Molloy, Nabila Youssouf, Tao Chen, Tinevimbo Shiri, Shabbar Jaffar, Thomas S Harrison, Joseph N Jarvis, Louis W Niessen, Jack Goodall, Kwana Lechiile, Norah Mawoko, Tshepiso Mbangiwa, James Milburn, Refilwe Mmipi, Ponego Ponatshego, Ikanyang Rulaganyang, Kaelo Seatla, Keatlaretse Siamisang, Nametso Tlhako, Katlego Tsholo, Samantha April, Abulele Bekiswa, Linda Boloko, Hloni Bookholane, Thomas Crede, Lee-Ann Davids, Rene Goliath, Siphokazi Hlungulu, Regina Hoffman, Henriette Kyepa, Noma Masina, Deborah Maughan, Trevor Mnguni, Sumaiyya Moosa, Tania Morar, Mkanyiseli Mpalali, Jonathan Naude, Ida Oliphant, Achita Singh, Sumaya Sayed, Leago Sebesho, Muki Shey, Loraine Swanepoel, Madalitso Chasweka, Wezi Chimang'anga, Tipatseni Chimphambano, Ebbie Gondwe, Henry Mzinganjira, Aubrey Kadzilimbile, Steven Kateta, Evelyn Kossam, Christopher Kukacha, Bright Lipenga, John Ndaferankhande, Maureen Ndalama, Reya Shah, Andreas Singini, Katherine Stott, Agness Zambasa, Towera Banda, Tarsizio Chikaonda, Gladys Chitulo, Lorren Chiwoko, Nelecy Chome, Mary Gwin, Timothy Kachitosi, Beauty Kamanga, Mussah Kazembe, Emily Kumwenda, Masida Kumwenda, Chimwemwe Maya, Wilberforce Mhango, Chimwemwe Mphande, Lusungu Msumba, Tapiwa Munthali, Doris Ngoma, Simon Nicholas, Lusayo Simwinga, Anthony Stambuli, Gerald Tegha, Janet Zambezi, Cynthia Ahimbisibwe, Andrew Akampurira, Anamudde Alice, Fiona Cresswell, Jane Gakuru, Enock Kagimu, John Kasibante, Daniel Kiiza, John Kisembo, Richard Kwizera, Florence Kugonza, Eva Laker, Tonny Luggya, Andrew Lule, Abdu Musubire, Rhona Muyise, Carol Olivie Namujju, Jane Francis Ndyetukira, Laura Nsangi, Michael Okirworth, Joshua Rhein, Morris K Rutakingirwa, Alisat Sadiq, Kenneth Ssebambulidde, Kiiza Tadeo, Asmus Tukundane, Leo Atwine, Peter Buzaare, Muganzi Collins, Ninsima Emily, Christine Inyakuwa, Samson Kariisa, James Mwesigye, Simpson Nuwamanya, Ankunda Rodgers, Joan Rukundo, Irene Rwomushana, Mike Ssemusu, Gavin Stead, Kathyrn Boyd, Secrecy Gondo, Prosper Kufa, Edward Makaha, Colombus Moyo, Takudzwa Mtisi, Shepherd Mudzinga, Constantine Mutata, Taddy Mwarumba, Tawanda Zinyandu, Alexandre Alanio, Francoise Dromer, Olivier Lortholary, Aude Sturny-Leclere, Philippa Griffin, Sophia Hafeez, Angela Loyse, Erik van Widenfelt

Publikováno v: The Lancet Global Health. 10:e1845-e1854

HIV-associated cryptococcal meningitis is a leading cause of AIDS-related mortality. The AMBITION-cm trial showed that a regimen based on a single high dose of liposomal amphotericin B deoxycholate (AmBisome group) was non-inferior to the WHO-recomme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399220405f85971ae16904f42ed5f4de
https://doi.org/10.1016/s2214-109x(22)00450-8

Early empiric anti

Autor: Bibie, Said, Edwin, Nuwagira, Alphonce, Liyoyo, Rinah, Arinaitwe, Catherine, Gitige, Rhina, Mushagara, Peter, Buzaare, Anna, Chongolo, Samuel, Jjunju, Precious, Twesigye, David R, Boulware, Mark, Conaway, Megan, Null, Tania A, Thomas, Scott K, Heysell, Christopher C, Moore, Conrad, Muzoora, Stellah G, Mpagama

Publikováno v: BMJ open. 12(6)

Sub-Saharan Africa shoulders the highest burden of global sepsis and associated mortality. In high HIV and tuberculosis (TB) prevalent settings such as sub-Saharan Africa, TB is the leading cause of sepsis. However, anti-TB therapy is often delayed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::077e17864145a8e072f0b2b056bbb4b1
https://pubmed.ncbi.nlm.nih.gov/35667721