Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Peter, Buske"'
Autor:
Peter Buske, Joerg Galle
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9781003339601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86713ab30aa6c238e20603f48e5cd88a
https://doi.org/10.1201/9781003339601-9
https://doi.org/10.1201/9781003339601-9
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 1, p e1001045 (2011)
We introduce a novel dynamic model of stem cell and tissue organisation in murine intestinal crypts. Integrating the molecular, cellular and tissue level of description, this model links a broad spectrum of experimental observations encompassing spat
Externí odkaz:
https://doaj.org/article/b719dc722ed64f1c995aec9525e3ec6d
Different in vivo and in vitro transformation of intestinal stem cells in mismatch repair deficiency
Autor:
Knut Krohn, Markus Loeffler, Peter Buske, Gabriela Aust, Henry Löffler-Wirth, Christiane Kerner, Karen Rother, T Kreutzmann, Jens Przybilla, Joerg Galle, K Keysselt
Publikováno v:
Oncogene. 36:2750-2761
Mutations in mismatch repair (MMR) genes result in microsatellite instability (MSI) and early onset of colorectal cancer. To get mechanistic insights into the time scale, sequence and frequency of intestinal stem cell (ISC) transformation, we quantif
Autor:
Hans, Binder, Lydia, Hopp, Michal R, Schweiger, Steve, Hoffmann, Frank, Jühling, Martin, Kerick, Bernd, Timmermann, Susann, Siebert, Christina, Grimm, Lilit, Nersisyan, Arsen, Arakelyan, Maria, Herberg, Peter, Buske, Henry, Loeffler-Wirth, Maciej, Rosolowski, Christoph, Engel, Jens, Przybilla, Martin, Peifer, Nicolaus, Friedrichs, Gabriela, Moeslein, Margarete, Odenthal, Michelle, Hussong, Sophia, Peters, Stefanie, Holzapfel, Jacob, Nattermann, Robert, Hueneburg, Wolff, Schmiegel, Brigitte, Royer-Pokora, Stefan, Aretz, Michael, Kloth, Matthias, Kloor, Reinhard, Buettner, Jörg, Galle, Markus, Loeffler
Publikováno v:
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2017, 243 (2), pp.242-254. ⟨10.1002/path.4948⟩
The Journal of pathology and bacteriology, John Wiley & Sons, 2017, 243 (2), pp.242-254. ⟨10.1002/path.4948⟩
Colorectal cancer (CRC) arising in Lynch syndrome (LS) comprises tumours with constitutional mutations in DNA mismatch repair genes. There is still a lack of whole-genome and transcriptome studies of LS-CRC to address questions about similarities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cd5f17c52c33352f1cd3a5ff330b5641
https://hal.archives-ouvertes.fr/hal-02517327
https://hal.archives-ouvertes.fr/hal-02517327
Publikováno v:
Biochemical Society Transactions. 42:671-677
The intestinal epithelium is permanently renewed during homoeostasis. Stable function of its stem cells is ensured by interaction with a specific tissue compartment, the so-called ‘intestinal stem cell niche’. The essential regulatory principles
Autor:
Sindy Oldenburg, Salah Amasheh, Markus Scholz, Olga N. Karpus, Doreen Sittig, Norman Dietrich, Jörg Hamann, Gabriela Aust, Hartmut Schneider, Susann Gonsior, Jörg Galle, Christiane Kerner, Peter Buske
Publikováno v:
Molecular biology of the cell, 24(14), 2256-2268. American Society for Cell Biology
Molecular Biology of the Cell
Molecular Biology of the Cell
Transgenic mice overexpressing CD97 in intestinal epithelial cells develop an upper megaintestine with normal microscopic morphology after birth and before weaning. Intestinal enlargement by CD97 depends on signaling but does not require binding of i
Publikováno v:
Frontiers in Life Science. 7:31-43
The stem cell epigenome reflects a delicate balance of chromatin (de-)modification processes. During cancer development this balance becomes disturbed, resulting in characteristic changes. Among them are changes of the DNA methylation profile. It has
Autor:
Hans Clevers, Markus Loeffler, Toshiro Sato, Peter Buske, Norman Sachs, Jens Przybilla, Joerg Galle
Publikováno v:
FEBS Journal. 279:3475-3487
In vitro culture of intestinal tissue has been attempted for decades. Only recently did Sato et al. [Sato, T., Vries, R. G., Snippert, H. J., van de Wetering, M., Barker, N., Stange, D. E., van Es, J. H., Abo, A., Kujala, P., Peters, P. J., et al. (2
Autor:
Peter, Buske, Jens, Przybilla, Markus, Loeffler, Norman, Sachs, Toshiro, Sato, Hans, Clevers, Joerg, Galle
Publikováno v:
The FEBS journal. 279(18)
In vitro culture of intestinal tissue has been attempted for decades. Only recently did Sato et al. [Sato, T., Vries, R. G., Snippert, H. J., van de Wetering, M., Barker, N., Stange, D. E., van Es, J. H., Abo, A., Kujala, P., Peters, P. J., et al. (2
On the impact of single cell biomechanics on the spatio-temporal organization of regenerative tissue
Publikováno v:
IFMBE Proceedings ISBN: 9783642038990
Collective phenomena in multi-cellular assemblies can be modeled on different levels of complexity. So-called agent-based or individual-based models (IBMs) consider the dynamics of each individual cell. As a special feature, these models allow to acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc3e354c8456605115b39a9cf1f759e
https://doi.org/10.1007/978-3-642-03900-3_54
https://doi.org/10.1007/978-3-642-03900-3_54