Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Peter, Bronk"'
Autor:
Brett C Baggett, Kevin R Murphy, Elif Sengun, Eric Mi, Yueming Cao, Nilufer N Turan, Yichun Lu, Lorraine Schofield, Tae Yun Kim, Anatoli Y Kabakov, Peter Bronk, Zhilin Qu, Patrizia Camelliti, Patrycja Dubielecka, Dmitry Terentyev, Federica del Monte, Bum-Rak Choi, John Sedivy, Gideon Koren
Publikováno v:
eLife, Vol 12 (2023)
Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and acce
Externí odkaz:
https://doaj.org/article/d202d60827684d86801b098db8759f70
Autor:
Anatoli Y. Kabakov, Elif Sengun, Yichun Lu, Karim Roder, Peter Bronk, Brett Baggett, Nilüfer N. Turan, Karni S. Moshal, Gideon Koren
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c9764b94a22347f4954b3aad64cf40e4
Autor:
Arvin H Soepriatna, Allison Navarrete-Welton, Tae Yun Kim, Mark C Daley, Peter Bronk, Celinda M Kofron, Ulrike Mende, Kareen L K Coulombe, Bum-Rak Choi
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280406 (2023)
Recent advances in human induced pluripotent stem cell (hiPSC)-derived cardiac microtissues provide a unique opportunity for cardiotoxic assessment of pharmaceutical and environmental compounds. Here, we developed a series of automated data processin
Externí odkaz:
https://doaj.org/article/2f97697e482841788bf25e944eb37c7d
Autor:
Anatoli Y. Kabakov, Elif Sengun, Yichun Lu, Karim Roder, Peter Bronk, Brett Baggett, Nilüfer N. Turan, Karni S. Moshal, Gideon Koren
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Cardiac arrhythmias significantly contribute to cardiovascular morbidity and mortality. The rabbit heart serves as an accepted model system for studying cardiac cell excitation and arrhythmogenicity. Accordingly, primary cultures of adult rabbit vent
Externí odkaz:
https://doaj.org/article/0c8d88d075894b5998ad6056eb883242
Autor:
Shanna Hamilton, Radmila Terentyeva, Tae Yun Kim, Peter Bronk, Richard T. Clements, Jin O-Uchi, György Csordás, Bum-Rak Choi, Dmitry Terentyev
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
In a physiological setting, mitochondria increase oxidative phosphorylation during periods of stress to meet increased metabolic demand. This in part is mediated via enhanced mitochondrial Ca2+ uptake, an important regulator of cellular ATP homeostas
Externí odkaz:
https://doaj.org/article/afd9fd2a470d40ac8bbdb50a6b5dfb09
Autor:
Peter Bronk, Tae Yun Kim, Yi Chun Lu, Nilufer Turan, Zhilin Qu, Radmila Terentyeva, Dmitry A. Terentyev, Gideon Koren, Bum-Rak Choi
Publikováno v:
Biophysical Journal. 122:255a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f42417f10027e346ad41c8d4be9dc6
https://doi.org/10.1016/j.bpj.2022.11.1473
https://doi.org/10.1016/j.bpj.2022.11.1473
Autor:
Peter Bronk, Karim Roder, Gideon Koren, Bum-Rak Choi, Dmitry Terentyev, Iuliia Polina, Richard T. Clements, Tae Yun Kim, Shanna Hamilton, Radmila Terentyeva
Publikováno v:
The Journal of Physiology
Key points Small‐conductance Ca2+‐activated K+ (SK) channels expressed in ventricular myocytes are dormant in health, yet become functional in cardiac disease.SK channels are voltage independent and their gating is controlled by intracellular [Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28466269f3dc5dd44b9a8d25ef5415e9
https://doi.org/10.1113/jp277618
https://doi.org/10.1113/jp277618
Autor:
Karni S. Moshal, Elif Sengun, Brett Baggett, Gideon Koren, Peter Bronk, Yichun Lu, Anatoli Y. Kabakov, Karim Roder, Nilüfer N. Turan
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Cardiac arrhythmias significantly contribute to cardiovascular morbidity and mortality. The rabbit heart serves as an accepted model system for studying cardiac cell excitation and arrhythmogenicity. Accordingly, primary cultures of adult rabbit vent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f02fb745364d1f31b7763303eaf9a74
https://pubmed.ncbi.nlm.nih.gov/34867432
https://pubmed.ncbi.nlm.nih.gov/34867432
Autor:
Zachary Pfeiffer, Katja E. Odening, Jung Min Hwang, Mingwang Zhong, Yichun Lu, Gideon Koren, Sridharan Rajamani, Alain Karma, Bum-Rak Choi, Yukiko Kunitomo, Luiz Belardinelli, Peter Bronk, Xuwen Peng, Tae Yun Kim, Anatoli Y. Kabakov, Karuppiah Arunachalam, Zhilin Qu, Dmitry Terentyev
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 13
Background: Long QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular tachycardias (PVTs). Suppressing the late sodium current (I NaL ) may counterbalance the reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25beb11cbee1d676415671525d5020f
https://doi.org/10.1161/circep.118.006875
https://doi.org/10.1161/circep.118.006875
Autor:
Jungmin, Hwang, Tae Yun, Kim, Dmitry, Terentyev, Mingwang, Zhong, Anatoli Y, Kabakov, Peter, Bronk, Karuppiah, Arunachalam, Luiz, Belardinelli, Sridharan, Rajamani, Yukiko, Kunitomo, Zachary, Pfeiffer, Yichun, Lu, Xuwen, Peng, Katja E, Odening, Zhilin, Qu, Alain, Karma, Gideon, Koren, Bum-Rak, Choi
Publikováno v:
Circulation. Arrhythmia and electrophysiology. 13(8)
Long QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular tachycardias (PVTs). Suppressing the late sodium current (IWe tested the effects of the selective IGS967 red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de912af5d6356adca1b1cfdaf8a5a29e
https://pubmed.ncbi.nlm.nih.gov/32628505
https://pubmed.ncbi.nlm.nih.gov/32628505