Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Peter, Braubach"'
Autor:
Aaqib Sohail, Fakhar H. Waqas, Peter Braubach, Laurien Czichon, Mohamed Samir, Azeem Iqbal, Leonardo de Araujo, Stephan Pleschka, Michael Steinert, Robert Geffers, Frank Pessler
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background The first 24 h of infection represent a critical time window in interactions between pathogens and host tissue. However, it is not possible to study such early events in human lung during natural infection due to lack of clinical
Externí odkaz:
https://doaj.org/article/7be4e3aef7e44bdc83d93facf4f88482
Autor:
Stevan D. Stojanović, Maximilian Fuchs, Chunguang Liang, Kevin Schmidt, Ke Xiao, Annette Just, Angelika Pfanne, Andreas Pich, Gregor Warnecke, Peter Braubach, Christina Petzold, Danny Jonigk, Jörg H. W. Distler, Jan Fiedler, Thomas Thum, Meik Kunz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The family of RNA-binding proteins (RBP) functions as a crucial regulator of multiple biological processes and diseases. However, RBP function in the clinical setting of idiopathic pulmonary fibrosis (IPF) is still unknown. We developed a pr
Externí odkaz:
https://doaj.org/article/757334abd2ab4df69064526720aa8b80
Autor:
Stephanie Dobersch, Karla Rubio, Indrabahadur Singh, Stefan Günther, Johannes Graumann, Julio Cordero, Rafael Castillo-Negrete, Minh Bao Huynh, Aditi Mehta, Peter Braubach, Hector Cabrera-Fuentes, Jürgen Bernhagen, Cho-Ming Chao, Saverio Bellusci, Andreas Günther, Klaus T. Preissner, Sita Kugel, Gergana Dobreva, Malgorzata Wygrecka, Thomas Braun, Dulce Papy-Garcia, Guillermo Barreto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The order of DNA methylation and histone modifications during transcription remained unclear. Here the authors show that HMGA2 induces DNA nicks at TGFB1-responsive genes, promoting nucleosome incorporation containing γ-H2AX, which is required for r
Externí odkaz:
https://doaj.org/article/c551a764a6c040d58f3cbdc0affd583b
Autor:
Stijn E. Verleden, Peter Braubach, Christopher Werlein, Edith Plucinski, Mark P. Kuhnel, Annemiek Snoeckx, Haroun El Addouli, Tobias Welte, Axel Haverich, Florian P. Laenger, Sabine Dettmer, Patrick Pauwels, Veronique Verplancke, Paul E. Van Schil, Therese Lapperre, Johanna M. Kwakkel-Van-Erp, Maximilian Ackermann, Jeroen M. H. Hendriks, Danny Jonigk
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Pathology and radiology are complimentary tools, and their joint application is often crucial in obtaining an accurate diagnosis in non-neoplastic pulmonary diseases. However, both come with significant limitations of their own: Computed Tomography (
Externí odkaz:
https://doaj.org/article/9d7fd2cd5ac24be39671d93b5803590a
Autor:
Muhammad Nasir Hayat Malik, Syed Fakhar-ul-Hassnain Waqas, Jana Zeitvogel, Jingyuan Cheng, Robert Geffers, Zeinab Abu-Elbaha Gouda, Ahmed Mahrous Elsaman, Ahmed R. Radwan, Matthias Schefzyk, Peter Braubach, Bernd Auber, Ruth Olmer, Mathias Müsken, Lennart M. Roesner, Gisa Gerold, Sven Schuchardt, Sylvia Merkert, Ulrich Martin, Felix Meissner, Thomas Werfel, Frank Pessler
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Ulcerating skin lesions are manifestations of human ISG15 deficiency, a type I interferonopathy. However, chronic inflammation may not be their exclusive cause. We describe two siblings with recurrent skin ulcers that healed with scar formation upon
Externí odkaz:
https://doaj.org/article/954f97e3aee74d59a2deee752c511caf
Autor:
Adrian Endres, Christian Hügel, Helena Boland, Michael Hogardt, Ralf Schubert, Danny Jonigk, Peter Braubach, Gernot Rohde, Carla Bellinghausen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Cystic fibrosis (CF) lung disease is aggravated by recurrent and ultimately chronic bacterial infections. One of the key pathogens in adult CF lung disease is P. aeruginosa (PA). In addition to bacteria, respiratory viral infections are suggested to
Externí odkaz:
https://doaj.org/article/fc242d79f65249b0be12fc2560df074d
Autor:
Melanie Albrecht, Olga Halle, Svenja Gaedcke, Sophia T Pallenberg, Julia Camargo Neumann, Marius Witt, Johanna Roediger, Marina Schumacher, Adan Chari Jirmo, Gregor Warnecke, Danny Jonigk, Peter Braubach, David DeLuca, Gesine Hansen, Anna‐Maria Dittrich
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 6, Pp n/a-n/a (2022)
Abstract Objectives The contribution of adaptive vs. innate lymphocytes to IL‐17A and IL‐22 secretion at the end stage of chronic lung diseases remains largely unexplored. In order to uncover tissue‐ and disease‐specific secretion patterns, w
Externí odkaz:
https://doaj.org/article/a2b279725f6d4aaf97e3f374eebea353
Autor:
Ruxandra Neatu, Ifeanyi Enekwa, Dean J. Thompson, Edward C. Schwalbe, Giorgio Fois, Gina Abdelaal, Stephany Veuger, Manfred Frick, Peter Braubach, Sterghios A. Moschos
Publikováno v:
Non-Coding RNA, Vol 8, Iss 6, p 83 (2022)
LncRNAs are involved in regulatory processes in the human genome, including gene expression. The rs35705950 SNP, previously associated with IPF, overlaps with the recently annotated lncRNA AC061979.1, a 1712 nucleotide transcript located within the M
Externí odkaz:
https://doaj.org/article/37e1aefca43d4134b2b902b6fae405d8
Autor:
Danny Jonigk, Helge Stark, Peter Braubach, Lavinia Neubert, Hoen‐oh Shin, Nicole Izykowski, Tobias Welte, Sabina Janciauskiene, Gregor Warnecke, Axel Haverich, Mark Kuehnel, Florian Laenger
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 5, Iss 4, Pp 256-271 (2019)
Abstract Interstitial lung diseases encompass a large number of entities, which are characterised by a small number of partially overlapping fibrosing injury patterns, either alone or in combination. Thus, the presently applied morphological diagnost
Externí odkaz:
https://doaj.org/article/5b3519a573004623a8241cb06b11aeed
Autor:
Adrian Kordes, Matthias Preusse, Sven D. Willger, Peter Braubach, Danny Jonigk, Axel Haverich, Gregor Warnecke, Susanne Häussler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Pseudomonas aeruginosa displays substantial genetic diversification across sub-compartments in cystic fibrosis (CF) lungs. Here, Kordes et al. show that, despite genetic variation, the ex vivo transcriptional profiles of P. aeruginosa populations are
Externí odkaz:
https://doaj.org/article/41109456e2284ab3b88bf9009b20cd58