Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Peter, Atadja"'
Autor:
Kapil N. Bhalla, Peter Atadja, Kyungsoo Ha, Stacey L. Hembruff, Jacqueline E. Smith, Lata Chauhan, Sreedhar Venkannagari, Uma Mudunuru, Warren Fiskus, Ramesh Balusu, Rekha Rao
PDF file - 56K, Chemical structures of panobinostat and chloroquine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e429a46c818b0e6b82b6c28aecc65403
https://doi.org/10.1158/1535-7163.22497441.v1
https://doi.org/10.1158/1535-7163.22497441.v1
Autor:
Kapil N. Bhalla, Peter Atadja, Kyungsoo Ha, Stacey L. Hembruff, Jacqueline E. Smith, Lata Chauhan, Sreedhar Venkannagari, Uma Mudunuru, Warren Fiskus, Ramesh Balusu, Rekha Rao
Histone deacetylase (HDAC) inhibitors (HDI) induce endoplasmic reticulum (ER) stress and apoptosis, while promoting autophagy, which promotes cancer cell survival when apoptosis is compromised. Here, we determined the in vitro and in vivo activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab82ed0996509c2bc9a07a7c3f5a3c5
https://doi.org/10.1158/1535-7163.c.6535620.v1
https://doi.org/10.1158/1535-7163.c.6535620.v1
Autor:
Ying Huang, Martin Sendzik, Jeff Zhang, Zhenting Gao, Yongfeng Sun, Long Wang, Justin Gu, Kehao Zhao, Zhengtian Yu, Lijun Zhang, Qiong Zhang, Joachim Blanz, Zijun Chen, Valérie Dubost, Douglas Fang, Lijian Feng, Xingnian Fu, Michael Kiffe, Ling Li, Fangjun Luo, Xiao Luo, Yuan Mi, Prakash Mistry, David Pearson, Alessandro Piaia, Clemens Scheufler, Remi Terranova, Andreas Weiss, Jue Zeng, Hailong Zhang, Jiangwei Zhang, Mengxi Zhao, Michael P. Dillon, Sebastien Jeay, Wei Qi, Jonathan Moggs, Carole Pissot-Soldermann, En Li, Peter Atadja, Andreas Lingel, Counde Oyang
Publikováno v:
Journal of Medicinal Chemistry. 65:5317-5333
Polycomb Repressive Complex 2 (PRC2) plays an important role in transcriptional regulation during animal development and in cell differentiation, and alteration of PRC2 activity has been associated with cancer. On a molecular level, PRC2 catalyzes me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8a2d3773ad89ebc7852a400a3f915e
https://doi.org/10.1021/acs.jmedchem.1c02148
https://doi.org/10.1021/acs.jmedchem.1c02148
Autor:
Karin Vanderkerken, Helena Jernberg-Wiklund, Ben Van Camp, Magnus Axelson, Olle Larsson, Peter Atadja, Anders Österborg, Elke De Bruyne, Els Van Valckenborgh, Eline Menu, Prasoon Agarwal, Charlotte Fristedt, Miguel Lemaire
PDF file - 60K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c5193c820a4500010d0f840762b611
https://doi.org/10.1158/1078-0432.22443767
https://doi.org/10.1158/1078-0432.22443767
Autor:
Patrick Schöffski, Gavino Faa, Agnieszka Wozniak, Peter Atadja, Kathleen Machiels, Steffen Fieuws, Cristiana Stefan, Raf Sciot, Maria Debiec-Rychter, Giuseppe Floris
Purpose: Histone deacetylase inhibitors have emerged as potent anticancer compounds. Using a nude-mouse xenograft model, for the first time we evaluated the response of human gastrointestinal stromal tumors (GIST) carrying different oncogenic KIT mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28039a9f69544916f17b0454d8d92f9d
https://doi.org/10.1158/1078-0432.c.6517830
https://doi.org/10.1158/1078-0432.c.6517830
Autor:
H. Miles Prince, Ricky W. Johnstone, Kenneth Culver, Margaret Dugan, Dale Butterfoss, Peter Atadja, Gail Ryan, Howard Burris, Joachim Beck, Monica Mita, Roxanne Williams-Truax, Chris McCormack, Daniel J. George, Gordon K. Smyth, Yan Pan, Leigh Ellis
Supplementary Tables 1-3 from Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463e094057a17a83cc864d0e83c33bc3
https://doi.org/10.1158/1078-0432.22439467.v1
https://doi.org/10.1158/1078-0432.22439467.v1
Autor:
Steven Grant, Paul Dent, Peter Atadja, Stefanie Coe, Sonia C. Maggio, Jorge A. Almenara, Roberto R. Rosato
Supplementary Fig. from Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d50acc1a3ce3de1fb7f7a38f268925
https://doi.org/10.1158/1535-7163.22484273.v1
https://doi.org/10.1158/1535-7163.22484273.v1
Autor:
Patrick Schöffski, Gavino Faa, Agnieszka Wozniak, Peter Atadja, Kathleen Machiels, Steffen Fieuws, Cristiana Stefan, Raf Sciot, Maria Debiec-Rychter, Giuseppe Floris
Supplementary Data from High Efficacy of Panobinostat Towards Human Gastrointestinal Stromal Tumors in a Xenograft Mouse Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dfbfabead89ca65c5223f405bb74d6
https://doi.org/10.1158/1078-0432.22440513.v1
https://doi.org/10.1158/1078-0432.22440513.v1
Autor:
Kapil Bhalla, Victor E. Marquez, Peter Atadja, Stacey L. Hembruff, Jacqueline E. Smith, Uma Mudunuru, Eduardo Sotomayor, Jianguo Tao, Siddhartha Ganguly, Ramesh Balusu, Rekha Rao, Warren Fiskus
PDF file, 659K, Supplemental Figure 1. Treatment with DZNep depletes expression of PRC2 proteins in MCL MO2058 and Z-138 cells. Supplemental Figure 2. Treatment with DZNep upregulates mRNA expression of EZH2 target genes in MCL cells.A-C. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31faf36e68913de6e4a28cc8a85ac622
https://doi.org/10.1158/1078-0432.22446656.v1
https://doi.org/10.1158/1078-0432.22446656.v1
Autor:
Kapil Bhalla, Victor E. Marquez, Peter Atadja, Stacey L. Hembruff, Jacqueline E. Smith, Uma Mudunuru, Eduardo Sotomayor, Jianguo Tao, Siddhartha Ganguly, Ramesh Balusu, Rekha Rao, Warren Fiskus
PDF file, 19K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834c44d5ffe872e3d4b715d03134336b
https://doi.org/10.1158/1078-0432.22446653
https://doi.org/10.1158/1078-0432.22446653