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pro vyhledávání: '"Pete Delgado"'
Akademický článek
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Autor:
K, Pallarito, P J, Kenkel, S, Lutz, E, Gardner, S, Taravella, J, Packer, J, Nemes, J, Greene, E, Berg, M, Wagner
Publikováno v:
Modern healthcare. 21(32)
Modern Healthcare's 1991 Up and Comers, the fifth annual group, are scattered all over the map, from Boston to the Bay Area, from Flint, Mich., to El Paso, Texas. They work in managed care, associations and specialty hospitals; one even administers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e652adb53f4b8aee82b0800b01c34b1b
https://pubmed.ncbi.nlm.nih.gov/10160762
https://pubmed.ncbi.nlm.nih.gov/10160762
Autor:
Jianwei Bian, James Roache, Sisi Zhang, Hui Wang, Jianhua Wang, Hongwei Yang, Tao Hong, Ruowei Mo, Feng Gao, Yizong Zhou, Cary Fridrich, Min Shi, Xiangguang Tian, Bin Wu, Pete Delgado, Jing Guo
Publikováno v:
Organic Process Research & Development. 24:2780-2788
The scalable synthesis of an FXI (Factor XI) inhibitor employing multiple emerging technologies is described. The reduction of ketone to chiral alcohol was established through a biocatalysis approa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f55cb33f8aba32b377cafb96ac88f81
https://doi.org/10.1021/acs.oprd.0c00412
https://doi.org/10.1021/acs.oprd.0c00412
Autor:
Kian L. Tan, Richard I. Robinson, Rohit Duvadie, Malte S. Mikus, Gina Geraci, Raoul J. Glass, Imran Elmaarouf, Pete Delgado, Dyuti Majumdar
Publikováno v:
The Journal of organic chemistry. 86(23)
Facilitating photoredox coupling reactions in process-friendly green solvents was achieved by the successful application of a dual Ir/Ni catalyst system with enhanced solubility properties. These photochemical reactions (specifically Br-Br sp2-sp3 cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed8a7bc8456886e1642a7facba19fd9
https://pubmed.ncbi.nlm.nih.gov/34808052
https://pubmed.ncbi.nlm.nih.gov/34808052
AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey
Autor:
Raymond E. Conrow, Mark R. Hellberg, David Earnest, Gary W. Williams, Pete Delgado, W. Dennis Dean, Najam A. Sharif, Peter G. Klimko, Michael S. Gaines, Karen S. Haggard, Robert D. Selliah, Marsha A. McLaughlin, Daniel Scott
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:4525-4528
A series of 11-oxa prostaglandin analogs was evaluated for FP receptor binding and activation. Several compounds having aryloxy-terminated lower chains were found to be potent agonists. Topical ocular dosing of AL-12182, the isopropyl ester prodrug o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaa7f878c1b411bce26660af3350532
https://doi.org/10.1016/j.bmcl.2004.06.037
https://doi.org/10.1016/j.bmcl.2004.06.037
Publikováno v:
Tetrahedron Letters. 49:2348-2350
A synthesis of the title compound, operable on kilogram scale, employs reductive acetylation of an N-acylindazole to give a hemiaminal acetate followed by deacetoxylation to the corresponding N-alkylindazole.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a437ede914ec10bf78c07c37736d921
https://doi.org/10.1016/j.tetlet.2008.02.086
https://doi.org/10.1016/j.tetlet.2008.02.086
Autor:
Jon C. Nixon, Karen S. Haggard, Mark R. Hellberg, Abdelmoula Namil, Karen C. David, Pete Delgado, Gustav Graff, Timothy L. Kessler
Publikováno v:
ChemInform. 30
A series of phenolic antioxidant ester and amide derivatives of the nonsteroidal antiinflammatory drug naproxen was designed to have both antiinflammatory and cytoprotective activity. Compounds were evaluated in vitro both for antioxidant activity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::896420cf05a48201ba3d5727affc6abb
https://doi.org/10.1002/chin.199922138
https://doi.org/10.1002/chin.199922138
Autor:
Karen C. David, Timothy L. Kessler, Mark R. Hellberg, Abdelmoula Namil, Jon C. Nixon, Pete Delgado, Gustav Graff, Karen S. Haggard
Publikováno v:
Journal of medicinal chemistry. 42(2)
A series of phenolic antioxidant ester and amide derivatives of the nonsteroidal antiinflammatory drug naproxen was designed to have both antiinflammatory and cytoprotective activity. Compounds were evaluated in vitro both for antioxidant activity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7237ab014784d9e5efa654f077299410
https://pubmed.ncbi.nlm.nih.gov/9925732
https://pubmed.ncbi.nlm.nih.gov/9925732
Autor:
Gary C. Chamness, Letitia C. Fulcher, Philip L. Stotter, B.R. Reddy, Pete Delgado, Mohammad Salman
Publikováno v:
Steroids. 56(7)
For the successful development of a high-affinity fluorophore-estradiol conjugate, the fluorophore must be attached to the estradiol molecule at a position that interferes least with its binding to the receptor. We have concentrated on 17 alpha subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eef45154da283f0a70149c8ec87c7e
https://pubmed.ncbi.nlm.nih.gov/1780954
https://pubmed.ncbi.nlm.nih.gov/1780954
Publikováno v:
Phosphorus and Sulfur and the Related Elements. 25:1-9
Thiol additions to 1,4-diarylsulfonyl-2-butynes result in stereoselective formation of 1,4-diarylsulfonyl-2-arylthio-2-butenes with a preponderance of the E isomer over the Z. Contrary to the behav...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b33dd5e7e653be3f9c9a7a25eb7743da
https://doi.org/10.1080/03086648508074250
https://doi.org/10.1080/03086648508074250