Výsledky vyhledávání - "Petal A. Wijnen"

Akademický článek

Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis

Autor: Bart de Brouwer, Marjolein Drent, Jody M. W. van den Ouweland, Petal A. Wijnen, Coline H. M. van Moorsel, Otto Bekers, Jan C. Grutters, Eric S. White, Rob Janssen

Publikováno v: Respiratory Research, Vol 19, Iss 1, Pp 1-4 (2018)

Abstract Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) seem to be opposite entities from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases. Emphysema is c

Externí odkaz: https://doaj.org/article/2f5e639a49a94369ae63118d0ec58551

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Drug-induced comorbidities in patients with sarcoidosis

Autor: Marjolein, Drent, Naomi T, Jessurun, Petal A, Wijnen, Otto, Bekers, Aalt, Bast

Publikováno v: Current Opinion in Pulmonary Medicine. 28:468-477

PURPOSE OF REVIEW: Sarcoidosis is a chronic multisystemic inflammatory disease of unknown aetiology with a wide range of highly variable clinical manifestations and unpredictable disease course. Sarcoidosis patients may present with specific organ-re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98fc9d124364177f413d1a728b74db0
https://doi.org/10.1097/mcp.0000000000000889

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Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients

Autor: Paola E. J. van der Meijden, Yvonne M. C. Henskens, Jurriën M Ten Berg, Leo Veenstra, Renske H. Olie, Minka J A Vries, Rachelle R K Hensgens, Hugo ten Cate, Otto Bekers, Petal A. Wijnen, Bianca T. A. de Greef

Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 3992, p 3992 (2021)
Journal of Clinical Medicine, 10(17):3992. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 10
Issue 17

On-treatment platelet reactivity in clopidogrel-treated patients can be measured with several platelet function tests (PFTs). However, the agreement between different PFTs is only slight to moderate. Polymorphisms of the CYP2C19 gene have an impact o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a769db40ce575412681532250c7fc53c
https://pubmed.ncbi.nlm.nih.gov/34501440

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Sarcoidosis and Work Participation

Autor: Marjolein Drent, Petal A. Wijnen, Celine Hendriks, J. de Vries, Marjon Elfferich, Lesley Ann Saketkoo

Publikováno v: Lung, 197, 407-413. Springer New York
Lung, 197(4), 407-413. Springer, Cham
Lung

ObjectiveSarcoidosis, an inflammatory multi-organ disease with a wide variety of clinical manifestations, affecting people of working age. Patients suffer from a broad spectrum of physical symptoms of varying severity that impact function including c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8e42c41c3a315cc374638a727578ae
https://doi.org/10.1007/s00408-019-00234-3

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Grapefruit Juice Facilitates Cortisol Replacement Therapy: Role of CYP3A Variant Alleles

Autor: Otto Bekers, Marjolein Drent, Petal A. Wijnen, Aalt Bast

Publikováno v: Archives of Clinical and Medical Case Reports.

Glucocorticosteroid (GC) replacement therapy is required in several clinical situations. However, tapering down the GC doses may lead to a steroid withdrawal syndrome. We describe the case of a patient presenting with Cushing’s syndrome due to a pi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcf8579ee02d631606511fa5e1ea2c70
https://doi.org/10.26502/acmcr.96550405

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Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers

Autor: Aalt Bast, Petal A. Wijnen, Naomi T Jessurun, Otto Bekers, Eugène van Puijenbroek, Marjolein Drent

Publikováno v: International Journal of Molecular Sciences, 21(8):2770. MDPI AG
International Journal of Molecular Sciences, Vol 21, Iss 2770, p 2770 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 8
International journal of molecular sciences, 21(8):2770. Multidisciplinary Digital Publishing Institute (MDPI)

Drugs are serious but underestimated causative agents of interstitial lung disease (ILD). Both cytotoxic and immune mechanisms may be involved in drug-induced ILD (DI-ILD). We aimed to investigate whether polymorphisms of relevant CYP enzymes involve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc39854c862db06235f8ecfce3c98971
https://research.rug.nl/en/publications/640fc5d1-91a0-4012-8bf9-945bd6330c84

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Pharmacogenetic variants and vitamin K deficiency: a risk factor or trigger for fibrosing interstitial pneumonias?

Autor: Aalt Bast, Petal A. Wijnen, Marjolein Drent

Publikováno v: Current Opinion in Pulmonary Medicine. 24(3):287-295

Purpose of review Fibrosing interstitial pneumonias are associated with various stages of fibrosis. The cause of this group of syndromes remains largely unknown. For most of these diseases, a genetic basis, environmental factors and certain triggers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa79f8c3545f4d499e38d58d4e50645f
https://www.ingentaconnect.com/content/wk/mcp/2018/00000024/00000003/art00012

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Role of Drug-Gene Interactions and Pharmacogenetics in Simvastatin-Associated Pulmonary Toxicity

Autor: Otto Bekers, Ankie M Harmsze, Petal A. Wijnen, Aalt Bast, Naomi T Jessurun, Eugène van Puijenbroek, Marjolein Drent

Publikováno v: Drug Safety
Drug Safety, 44(11), 1179-1191. Adis International Ltd
Drug Safety, 44. ADIS INT LTD

Introduction Simvastatin has previously been associated with drug-induced interstitial lung disease. In this retrospective observational study, cases with non-specific interstitial pneumonia (NSIP) or idiopathic pulmonary fibrosis (IPF) with simvasta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd9f3c9fae15b3bf5b2d59725296e0c
https://doi.org/10.1007/s40264-021-01105-8

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