Design, Synthesis, and Biological Evaluation of (+)‐Camphor‐ and (−)‐Fenchone‐Based Derivatives as Potent Orthopoxvirus Inhibitors.

Autor: Sokolova, Anastasiya S., Kovaleva, Kseniya S., Kuranov, Sergey O., Bormotov, Nikolay I., Borisevich, Sophia S., Zhukovets, Anastasiya A., Yarovaya, Olga I., Serova, Olga A., Nawrozkij, Maxim B., Vernigora, Andrey A., Davidenko, Andrey V., Khamitov, Eduard M., Peshkov, Roman Y., Shishkina, Larisa N., Maksuytov, Rinat A., Salakhutdinov, Nariman F.

Publikováno v: ChemMedChem; 6/20/2022, Vol. 17 Issue 12, p1-25, 25p

Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3.

Autor: Sherstyuk YV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Ivanisenko NV; Federal Research Centre, Institute of Cytology and Genetics SB RAS, Lavrent'ev Ave, 10, 630090 Novosibirsk, Russia., Zakharenko AL; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Sukhanova MV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Peshkov RY; Novosibirsk State University, Pirogova St., 2, 630090 Novosibirsk, Russia., Eltsov IV; Novosibirsk State University, Pirogova St., 2, 630090 Novosibirsk, Russia., Kutuzov MM; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Kurgina TA; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Belousova EA; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Ivanisenko VA; Federal Research Centre, Institute of Cytology and Genetics SB RAS, Lavrent'ev Ave, 10, 630090 Novosibirsk, Russia., Lavrik OI; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Silnikov VN; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia., Abramova TV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Lavrent'ev Ave, 8, 630090 Novosibirsk, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 27; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 27.