Night vision restored in days after decades of congenital blindness

Autor: Jacobson, Samuel G., Cideciyan, Artur V., Ho, Allen C., Roman, Alejandro J., Wu, Vivian, Garafalo, Alexandra V., Sumaroka, Alexander, Krishnan, Arun K., Swider, Malgorzata, Mascio, Abraham A., Kay, Christine N., Yoon, Dan, Fujita, Kenji P., Boye, Sanford L., Peshenko, Igor V., Dizhoor, Alexander M., Boye, Shannon E.

Publikováno v: In iScience 21 October 2022 25(10)

Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations

Autor: Jacobson, Samuel G., Cideciyan, Artur V., Ho, Allen C., Peshenko, Igor V., Garafalo, Alexandra V., Roman, Alejandro J., Sumaroka, Alexander, Wu, Vivian, Krishnan, Arun K., Sheplock, Rebecca, Cheang, Bee-Lin, Davidson, Vanessa, O’Riordan, Catherine R., Boye, Sanford L., Dizhoor, Alexander M., Boye, Shannon E.

Publikováno v: In iScience 15 November 2024 27(11)

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Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four helix bundle

Autor: Peshenko, Igor V, Yu, Qinhong, Lim, Sunghyuk, Cudia, Diana, Dizhoor, Alexander M, Ames, James B

Publikováno v: Peshenko, Igor V; Yu, Qinhong; Lim, Sunghyuk; Cudia, Diana; Dizhoor, Alexander M; & Ames, James B. (2018). Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four helix bundle.. The Journal of biological chemistry, jbc.RA118.006106-jbc.RA118.006106. doi: 10.1074/jbc.ra118.006106. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/60k006zb

Retinal degeneration 3 (RD3) protein promotes accumulation of retinal membrane guanylyl cyclase (RetGC) in photoreceptor outer segment and suppresses RetGC activation by guanylyl cyclase activating proteins (GCAPs). Mutations truncating RD3 cause sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::02283f96805cf5c93152a8c546ed6881
http://www.escholarship.org/uc/item/60k006zb