Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Pervin Anklesaria"'
Autor:
Pervin Anklesaria, Nina D. Russell
Publikováno v:
Journal of the International AIDS Society, Vol 26, Iss 5, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/5f68bd634b5340738264be2588e0af28
Autor:
Holly Prudden, Roger Tatoud, Cathy Slack, Robin Shattock, Pervin Anklesaria, Linda-Gail Bekker, Susan Buchbinder
Publikováno v:
Vaccines, Vol 11, Iss 5, p 970 (2023)
The development of safe and effective HIV vaccines has been a scientific challenge for more than 40 years. Despite disappointing results from efficacy clinical trials, much has been learnt from years of research and development. In a rapidly evolving
Externí odkaz:
https://doaj.org/article/809d7483d34a4a71bae0685caae6f520
Autor:
Daniel E. Furst, Arthur Bookman, Kathryn Hobbs, Edward C. Keystone, Alison E. Heald, Philip J. Mease, Andrew Chalmers, Pervin Anklesaria, Hani El-Gabalawy
Publikováno v:
Annals of the Rheumatic Diseases. 68:1247-1254
Objective: To examine the safety and tolerability of a single intra-articular injection of rAAV2-TNFR:Fc, an adenoassociated virus serotype 2 vector containing the cDNA for the human tumour necrosis factor–immunoglobulin Fc fusion gene (tgAAC94), i
Autor:
Jennifer Lehrman, Burc Barin, Eva Vets, Alison E. Heald, Jill Gilmour, Pervin Anklesaria, Mathieu Peeters, Ramesh S. Paranjape, C. Schmidt, Carolynne Schwarze-Zander, Sanjay Mehendale, Jean-Louis Excler, Kabeya Kabamba, Nathan Clumeck, Jan van Lunzen, Madhuri Thakar, Tobias Glaunsinger, Philip R. Johnson, Mark Boaz, Seema Sahay, Sonali Kochhar, Jürgen K. Rockstroh, Patricia E. Fast
Publikováno v:
Aids Research and Human Retroviruses, 24(6), 873-880
A novel prophylactic AIDS vaccine candidate, consisting of single-stranded DNA for HIV-1 subtype C gag, protease, and part of reverse transcriptase genes, enclosed within a recombinant adeno-associated virus serotype-2 protein capsid (tgAAC09) induce
Publikováno v:
The Journal of Gene Medicine. 9:10-21
Background Cystic fibrosis is an autosomal recessive disease affecting approximately 1 in 2500 live births. Introducing the cDNA that codes for normal cystic fibrosis transmembrane conductance regulator (CFTR) to the small airways of the lung could r
Autor:
Kevin J. Furstoss, Ralph Paul, Pierrot Harvie, Jason Orthel, Elise Mebel, Elizabeth Bruckheimer, Pervin Anklesaria, Benjamin Dutzar
Publikováno v:
Cancer Gene Therapy. 11:128-134
Gene therapy utilizing lipid-based delivery systems holds tremendous promise for the treatment of cancer. However, due to the potential adverse inflammatory and/or immune effects upon systemic administration, treatments thus far have been predominant
Publikováno v:
Human Gene Therapy. 8:1685-1694
High transduction frequency of hematopoietic stem/progenitor cells is essential to derive clinical benefits for treating certain inherited and acquired diseases. We demonstrate here stable gene transfer into human bone marrow-derived CD34+ progenitor
Autor:
Peter E. Newburger, Pervin Anklesaria, Richard C. Woodman, John T. Curnutte, Julie Rae, Myron S. Cohen, Richard W. Erickson
Publikováno v:
Blood. 85:231-241
Chronic granulomatous disease (CGD) is characterized by recurrent infections, and is usually associated with a complete inability of phagocytic cells to generate superoxide anion (O2-). Rarely, variant forms of CGD have been reported in which there i
Autor:
Thomas J. Fitzgerald, Mary Ann Sakakeeny, Pierre Laneuville, Joel S. Greenberger, Pervin Anklesaria, M.A. Santucci, Indra J. Das
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 26:831-836
Purpose: The cytogenetic finding of the Ph1+ chromosome and its molecular biologic marker bcr/abl gene rearrangement in cells from patients with chronic myeloid leukemia are associated with a proliferative advantage of the Ph1+ clone in vivo. Althoug
Autor:
M.A. Santucci, Christie A. Holland, Joel S. Greenberger, Pervin Anklesaria, B S Mary Ann Sakakeeny, Indra J. Das, Thomas J. Fitzgerald, Michael G. McKenna
Publikováno v:
Radiation Oncology Investigations. 1:131-136
Human T-cell leukemia virus type I (HTLV-1) is the etiologic agent for adult T-cell leukemia (ATL). Among the X region products of HTLV-1, the p42 kDa protein Tax was identified, as responsible for cell immortalization and transformation. However, th