Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Perumal Sivashanmugam"'
Publikováno v:
SLAS Discovery. 18:1132-1137
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is an important regulator of ion transport and fluid secretion in humans. Mutations to CFTR cause cystic fibrosis, which is a common recessive genetic disorder in Caucasians. Invo
Autor:
Lisheng Zhang, Neil J. Freedman, Perumal Sivashanmugam, Eric S. Orman, Karsten Peppel, Leigh Brian, Sabrina T. Exum
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1087-1094
Objective— Mechanisms by which tumor necrosis factor-α (TNF) contributes to atherosclerosis remain largely obscure. We therefore sought to determine the role of the arterial wall TNF receptor-1 (TNFR1) in atherogenesis. Methods and Results— Caro
Autor:
Perumal Sivashanmugam, Christopher J. Sample, Yehia Daaka, Puneeta Arora, Babak Baban, Nader H. Moniri, Neetu Sud, Elizabeth A. Kasbohm, Rishu Guo
Publikováno v:
Endocrinology. 147:4883-4892
The bioactive phospholipid lysophosphatidic acid (LPA) promotes cell proliferation, survival, and migration by acting on cognate G protein-coupled receptors named LPA(1), LPA(2), and LPA(3). We profiled gene expression of LPA receptors in androgen-de
Autor:
Perumal Sivashanmugam, Michael G. O'Rand, Richard T. Richardson, Zengjun Wang, Esther E. Widgren
Publikováno v:
Biology of Reproduction. 72:1064-1070
Eppin (SPINLW1; GeneID, 57119) is a single-copy gene encoding a cysteine-rich protein found only in the testis and epididymis, which contains both Kunitz-type and WAP-type four disulfide core protease inhibitor consensus sequences. This study demonst
Autor:
Zengjun Wang, Suresh Yenugu, Frank S. French, Susan H. Hall, Perumal Sivashanmugam, Richard T. Richardson, Michael G. O'Rand
Publikováno v:
Biology of Reproduction. 71:1484-1490
The role of epididymal sperm-binding proteins in reproductive tract immunity is now well recognized in addition to their role in sperm maturation. Spermatozoa acquire forward motility and fertilizing ability during their passage through the epididymi
Publikováno v:
Journal of Biological Chemistry. 279:21154-21159
The interaction between stromal and epithelial cells is critical for the initiation and progression of prostate cancer, but the molecular determinants responsible for the cross-talk between these two cell types remain largely unknown. Here, we used a
Autor:
Michael G. O'Rand, Gail Grossman, Perumal Sivashanmugam, Peter Petrusz, Yonglian Zhang, Rama Soundararajan, Katherine G. Hamil, Qiang Liu, Susan H. Hall, Frank S. French, Richard T. Richardson, Suresh Yenugu
Publikováno v:
Endocrinology. 143:2787-2796
Cystatin (CST)11, a novel member of the CST type 2 family of cysteine protease inhibitors, was identified in Macaca mulatta epididymis by subtractive hybridization cloning. The human CST11 gene on chromosome 20p11.2 is located near three other CST ge
Publikováno v:
Biology of Reproduction. 65:1691-1700
Zonadhesin is a multiple-domain transmembrane protein that is believed to function as a sperm-zona pellucida binding protein. In this study we sequenced zonadhesin from rabbit testis and analyzed its processing, expression, localization, and zona pel
Autor:
David C. Crossman, Elizabeth R. Hauser, Neil J. Freedman, Liyong Wang, Christopher B. Granger, Jeffery M. Vance, David Seo, Pascal J. Goldschmidt-Clermont, Simon G. Gregory, Christopher J. Jones, Perumal Sivashanmugam, Carol Haynes, Margaret A. Pericak-Vance, William E. Kraus, Jonathan L. Haines, Svati H. Shah, Sabrina T. Exum
Previous association mapping on chromosome 3q13-21 detected evidence for association at the limbic system-associated membrane protein (LSAMP) gene in individuals with late-onset coronary artery disease (CAD). LSAMP has never been implicated in the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5018763feb8811245f37cff92451da
https://europepmc.org/articles/PMC2652886/
https://europepmc.org/articles/PMC2652886/
Autor:
A. Jagannadha Rao, Susan H. Hall, Michael G. O'Rand, V. Ramesh, Richard T. Richardson, Esther E. Widgren, Perumal Sivashanmugam, Frank S. French, C. A. VandeVoort, S. G. Ramachandra
Publikováno v:
IndraStra Global.
Various forms of birth control have been developed for women; however, there are currently few options for men. The development of male contraceptives that are effective, safe, and reversible is desired for family planning throughout the world. We no