Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Perumal, Yogeeswari"'
Autor:
Purbali Chakraborty, Syeda Lubna, Shouvik Bhuin, Deepika K., Manab Chakravarty, Trinath Jamma, Perumal Yogeeswari
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The pursuit of small molecule inhibitors targeting hexokinase 2 (HK2) has significantly captivated the field of cancer drug discovery. Nevertheless, the creation of selective inhibitors aimed at specific isoforms of hexokinase (HK) remains a formidab
Externí odkaz:
https://doaj.org/article/794a70d147954a7fa5aa5e05cc2fa07e
Autor:
Francine Kengne Mediesse, Thaddée Boudjeko, Anantharaju Hasitha, Matharasala Gangadhar, Wilfred Fon Mbacham, Perumal Yogeeswari
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional medicine for the treatment of inflammatory diseases. Several studies have
Externí odkaz:
https://doaj.org/article/cf230ff40a1c46b0893d8da74ee518f9
Publikováno v:
Future Medicinal Chemistry. 14:463-478
Background: Epidermal growth factor receptor-tyrosine kinase (EGFR-TK) is a well-known hallmark of oral and oropharyngeal cancers, as its overexpression leads to poor prognosis and malignancy. The activating EGFR mutations (particularly T790M and L85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f65cfaeee4086be67f76ccfe45e4ab0
https://doi.org/10.4155/fmc-2021-0205
https://doi.org/10.4155/fmc-2021-0205
Benzothiazinone-piperazine derivatives as efficient Mycobacterium tuberculosis DNA gyrase inhibitors
Autor:
Manoj Chandran, Janupally Renuka, Jonnalagadda Padma Sridevi, Ganesh S Pedgaonkar, Vanaparthi Asmitha, Perumal Yogeeswari, Dharmarajan Sriram
Publikováno v:
International Journal of Mycobacteriology, Vol 4, Iss 2, Pp 104-115 (2015)
Background and objectives: Bacterial DNA topoisomerases are unique in maintaining the DNA topology for cell viability. Mycobacterium tuberculosis (MTB) DNA gyrase, a sole type II topoisomerase has a larger scope as a target for developing novel thera
Externí odkaz:
https://doaj.org/article/75ea5bd0e2334e23a8d2f38b31482be6
Akademický článek
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Autor:
Jonnalagadda Padma Sridevi, Hasitha Shilpa Anantaraju, Pushkar Kulkarni, Perumal Yogeeswari, Dharmarajan Sriram
Publikováno v:
International Journal of Mycobacteriology, Vol 3, Iss 4, Pp 259-267 (2014)
Introduction: Mycobacterium marinum has emerged as a suitable species for induction of tuberculosis-like disease in zebrafish, and various zebrafish models (larval and adult) for drug screening have been proposed in the literature. It is believed tha
Externí odkaz:
https://doaj.org/article/ccd448d589ad4399bdd20fe574ecdf35
Autor:
Ganesh Samala, Shruti Singh Kakan, Radhika Nallangi, Parthiban Brindha Devi, Jonnalagadda Padma Sridevi, Shalini Saxena, Perumal Yogeeswari, Dharmarajan Sriram
Publikováno v:
International Journal of Mycobacteriology, Vol 3, Iss 2, Pp 117-126 (2014)
Background and objectives: The objective of this study is to synthesize and evaluate 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione (CD59) analogues to establish structure–activity relationship and mechanism of
Externí odkaz:
https://doaj.org/article/b02393494cb741f7a4e55127ed4effd0
Autor:
Francis Desire Tatsinkou Bomba, Madhu Babu Battu, Gangadhar Matharasala, Perumal Yogeeswari, Dharmarajan Sriram, Télesphore Benoît Nguelefack, Albert Kamanyi, Ram Kumar Mishra
Publikováno v:
Inflammopharmacology. 29:1241-1253
Petersianthus macrocarpus (Lecythidaceae) stem bark is traditionally used in West and Central Africa for the treatment of boils and pain. The present study examined the chemical composition of the aqueous and methanolic stem bark extracts of P. macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12ffd6a5f7c6f1698426f5e5e746c88f
https://doi.org/10.1007/s10787-021-00821-y
https://doi.org/10.1007/s10787-021-00821-y
Autor:
Veesam, Hema, Avula, Prameela Rani, Challa, Siva Reddy, Matharasala, Gangadhar, Perumal, Yogeeswari, Dharmarajan, Sriram
Publikováno v:
In Journal of Pharmacy Research July 2013 6(7):780-784
Publikováno v:
Journal of Advances in Biology & Biotechnology. :23-32
Aims: To determine the effects of polysaccharide fractions named KGF and CCF respectively for Khaya grandifoliola stem bark and Cymbopogon citratus leaves on Central Nervous System (CNS) depression and on systemic lipopolysaccharide (LPS)-induced bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840081429a3710be8a70a1c3a4c005d7
https://doi.org/10.9734/jabb/2020/v23i530156
https://doi.org/10.9734/jabb/2020/v23i530156