Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Perspective and Reflection Article"'
Publikováno v:
Cell Stress Chaperones
For several decades, the somatic mutation theory (SMT) has been the dominant paradigm on cancer research, leading to the textbook notion that cancer is fundamentally a genetic disease. However, recent discoveries indicate that mutations, including
Autor:
Jill L. Johnson, Marissa E. Dean
Publikováno v:
Cell Stress Chaperones
The Hsp90 molecular chaperone is required for the function of hundreds of different cellular proteins. Hsp90 and a cohort of interacting proteins called cochaperones interact with clients in an ATP-dependent cycle. Cochaperone functions include targe
Publikováno v:
Cell Stress and Chaperones. 24:289-293
Searching the literature is often overlooked and receives inadequate attention. In this article, we seek to address this issue by presenting several strategies. Here, five steps are outlined and discussed to facilitate effective literature searching.
Autor:
Antonio De Maio, Lawrence E. Hightower
Publikováno v:
Cell Stress Chaperones
The successful function of cells is importantly contributed by lipid membranes that are more than a simple physical barrier. The major components of cellular membranes are lipids, in particular glycerophospholipids, that have the capacity to assemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a37561e56806f878f79e5624419fc2
https://europepmc.org/articles/PMC7736428/
https://europepmc.org/articles/PMC7736428/
Autor:
Philip L. Hooper
Publikováno v:
Cell Stress and Chaperones
Cell Stress & Chaperones
Cell Stress & Chaperones
The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low intrace
Autor:
Antonella D'Anneo, Celeste Caruso Bavisotto, Daniela Carlisi, Alberto J.L. Macario, Letizia Paladino, Antonella Marino Gammazza, Everly Conway de Macario, Marianna Lauricella, Francesco Cappello
Publikováno v:
Cell Stress & Chaperones
Fatty acid–binding proteins (FABPs) are lipid chaperones assisting in the trafficking of long-chain fatty acids with functions in various cell compartments, including oxidation, signaling, gene-transcription regulation, and storage. The various kno
Publikováno v:
Cell Stress & Chaperones
Cell Stress and Chaperones
Cell Stress and Chaperones
Near the end of 2019, SARS-CoV-2, a novel highly contagious coronavirus phylogenetically related to the SARS virus, entered the human population with lethal consequences. This special issue devoted to the resulting disease COVID-19 was not planned bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44214c582adc0d24ac9a3ca7f5b60ddc
http://hdl.handle.net/2108/261569
http://hdl.handle.net/2108/261569
Autor:
Charles Giardina, Lawrence E. Hightower, Caesar Anderson, George A. Perdrizet, Lauren E Harrison
Publikováno v:
Cell Stress and Chaperones. 23:1143-1152
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure in the western world. Current treatment of diabetic kidney disease relies on nutritional management and drug therapies to achieve metabolic control. Here, we discuss the po
Publikováno v:
Cell Stress and Chaperones. 23:807-812
Plant response to water stress involves the activation of mechanisms expected to help them cope with water scarcity. Among these mechanisms, proteome-wide adjustment is well known. This includes actions to save energy, protect cellular and molecular
Autor:
Nektarios Barabutis
Publikováno v:
Cell Stress Chaperones
Heat shock protein 90 is a highly conserved molecular chaperone, essential for cellular survival under diverse environments. Since this protein is employed by tumors to promote their prevalence, heat shock protein 90 inhibitors have been developed to