Zobrazeno 1 - 10
of 3 470
pro vyhledávání: '"Personalized Therapy"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Neddylation, as a post-translational modification, has garnered significant attention in various tumor types recently. Few studies have investigated the involvement of neddylation-related genes (NRGs) in cutaneous melanoma (CM). Our study ai
Externí odkaz:
https://doaj.org/article/14d031dbb03a4d588c3c9a93a604c76a
Autor:
Georgian-Longin Iacobescu, Antonio-Daniel Corlatescu, Bogdan Serban, Razvan Spiridonica, Horia Petre Costin, Catalin Cirstoiu
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 12658-12671 (2024)
The chondrosarcoma, a cartilage-forming bone tumor, presents significant clinical challenges due to its resistance to chemotherapy and radiotherapy. Surgical excision remains the primary treatment, but high-grade chondrosarcomas are prone to recurren
Externí odkaz:
https://doaj.org/article/f27b77cca3a34f6dae4d430744139c8c
Autor:
Tingting Guo, Shuai Zhang, Weiping Zeng, Yan Liang, Jinghe Xie, ShouPei Liu, Yaqi Qiu, Yingjie Fu, Yimeng Ou, Keqiang Ma, Bailin Wang, Weili Gu, Yuyou Duan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Liver cancer stem cells (LCSCs) are thought to drive the metastasis and recurrence, however, the heterogeneity of molecular markers of LCSCs has hindered the development of effective methods to isolate them. Methods This study int
Externí odkaz:
https://doaj.org/article/1dd9e555d1f544f3902e65ff9c35ff0d
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Breast cancer remains a leading cause of mortality among women worldwide, necessitating innovative prognostic models to enhance treatment strategies. Methods Our study retrospectively enrolled 9,439 breast cancer patients from 12
Externí odkaz:
https://doaj.org/article/9f022dbadf3b4eb482a027f296c9d2c1
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Many palliative cancer patients require inpatient hospital treatment for medical reasons, which contrasts their frequent desire to be at home. Virtual reality (VR) could be a way of bringing the home environment closer to them. Fi
Externí odkaz:
https://doaj.org/article/5dc475ac64a24510851aec32d9f0288f
Autor:
Christina Gerlach, Laura Haas, Anja Greinacher, Jonah Lantelme, Melanie Guenther, Julia Thiesbonenkamp-Maag, Bernd Alt-Epping, Cornelia Wrzus
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Cancer patients benefit from Virtual Reality (VR) in burdensome situations, but evidence is scarce for palliative situations. Based on earlier work in palliative care, individualized VR interventions like seeing the patient’s ho
Externí odkaz:
https://doaj.org/article/7821a62f5deb4b498c3b61014c7c3f56
Autor:
Irina V. Menshikova
Publikováno v:
Терапевтический архив, Vol 96, Iss 8, Pp 820-825 (2024)
The review briefly presents modern understanding heterogeneity of osteoarthritis (OA) which is based on pathophysiological features of its variants. The concept of the phenotypes and endotypes of OA reflects these differences. In clinical recommendat
Externí odkaz:
https://doaj.org/article/3cee42746e784149a4bbd242de9b3943
Autor:
Adele Tanzi, Lola Buono, Cristina Grange, Corinne Iampietro, Alessia Brossa, Fanny Oliveira Arcolino, Maddalena Arigoni, Raffaele Calogero, Laura Perin, Silvia Deaglio, Elena Levtchenko, Licia Peruzzi, Benedetta Bussolati
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Personalized disease models are crucial for evaluating how diseased cells respond to treatments, especially in case of innovative biological therapeutics. Extracellular vesicles (EVs), nanosized vesicles released by cells for inte
Externí odkaz:
https://doaj.org/article/1d0980a33a23454f942994924d92a61f
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEarly detection of oral squamous cell carcinoma (OSCC) is critical for improving clinical outcomes. Precision diagnostics integrating metabolomics and machine learning offer promising non-invasive solutions for identifying tumor-derived b
Externí odkaz:
https://doaj.org/article/fc49f65a49da430093e520239d9bc3ca
Autor:
Priyanka Guha, Siddhartha Dutta, Krishna Murti, Jay Karan Charan, Krishna Pandey, V. Ravichandiran, Sameer Dhingra
Publikováno v:
Medicine in Omics, Vol 12, Iss , Pp 100033- (2024)
Tuberculosis (TB) continues to be a global health problem due to its high morbidity and death rates. Standardized regimens have been used in traditional TB treatment methods, frequently leading to less-than-ideal results and the establishment of drug
Externí odkaz:
https://doaj.org/article/ec48aeeb24e1462ab7be317387457d17