Zobrazeno 1 - 10
of 3 910
pro vyhledávání: '"Personalised Medicine"'
Autor:
Kasshish Mehta, Mangala Hegde, Sosmitha Girisa, Ravichandran Vishwa, Mohammed S. Alqahtani, Mohamed Abbas, Mehdi Shakibaei, Gautam Sethi, Ajaikumar B. Kunnumakkara
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-25 (2024)
Abstract The extensive heterogeneity and the limited availability of effective targeted therapies contribute to the challenging prognosis and restricted survival observed in triple-negative breast cancer (TNBC). Recent research indicates the aberrant
Externí odkaz:
https://doaj.org/article/115a9fb9250e40cba2910b5b0fb8a51c
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 10, Pp 01-05 (2024)
The healthcare landscape has undergone a profound transformation due to digitalisation in recent decades, shifting from manual practices to automated processes. Digital biomarkers have become increasingly important in healthcare across multiple domai
Externí odkaz:
https://doaj.org/article/ca24ef3286694b808f32b0ffa3d0a808
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 4, Pp 400-410 (2024)
INTRODUCTION. National pharmacy compounding is a priority for providing the population with medicinal products, particularly the medicinal products lacking in the Russian Federation. Investigating opportunities to improve the operation of compounding
Externí odkaz:
https://doaj.org/article/e718f641331d4b28a9d9117245de5151
Autor:
David R. Skvarc, Trang T. T. Truong, Robert M. Lundin, Russell Barnes, Fiona A. Wilkes, Ajeet B. Singh
Publikováno v:
Future Pharmacology, Vol 4, Iss 3, Pp 574-589 (2024)
Genetic factors influence medication response (pharmacogenetics), affecting the pharmacodynamics and pharmacokinetics of many medicaments used in clinical care. The ability of medications to cross the blood–brain barrier (BBB) represents a critical
Externí odkaz:
https://doaj.org/article/50ca553e03a74fbc9176d9fd5df7fb24
Autor:
Amali Mallawaarachchi, Erik Biros, Trudie Harris, Bruce Bennetts, Tiffany Boughtwood, Justine Elliott, Lindsay Fowles, Robert Gardos, Denisse Garza, Ilias Goranitis, Matilda Haas, Vanessa Huntley, Julia Jefferis, Karin Kassahn, Anna Leaver, Ben Lundie, Sebastian Lunke, Caitlin O’Connor, Greg Pratt, Catherine Quinlan, Dianne Shearman, Jacqueline Soraru, Madhivanan Sundaram, Michel Tchan, Giulia Valente, Julie White, Ella Wilkins, Steve I. Alexander, Noa Amir, Stephanie Best, Hossai Gul, Kushani Jayasinghe, Hugh McCarthy, Chirag Patel, Zornitza Stark, Andrew J. Mallett
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-10 (2024)
Abstract The KidGen Collaborative's Policy Implementation Workshop 2023 celebrated the 10th anniversary of Australia's first kidney genetics clinic in Brisbane. This event marked the establishment of a national network now comprising 19 kidney geneti
Externí odkaz:
https://doaj.org/article/6b39209f4a084172b3ad6ace312cfc5e
Autor:
Riya Khetan, Preethi Eldi, Noor A. Lokman, Carmela Ricciardelli, Martin K. Oehler, Anton Blencowe, Sanjay Garg, Katherine Pillman, Hugo Albrecht
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Genetic heterogeneity in ovarian cancer indicates the need for personalised treatment approaches. Currently, very few G-protein coupled receptors (GPCRs) have been investigated for active targeting with nanomedicines such as antibody-conjuga
Externí odkaz:
https://doaj.org/article/c01647f0a122462aaa86f0867aefdd8e
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Introduction n-of-1 trials are undertaken to optimise the evaluation of health technologies in individual patients. They involve a single patient receiving treatments, both interventional and control, consecutively over set periods of time,
Externí odkaz:
https://doaj.org/article/89a52fd62e804f53b2619e2a255f6b18
Autor:
I. P. Shilovskiy, G. B. Pasikhov, V. V. Smirnov, I. A. Kofiadi, M. V. Popova, P. A. Strueva, M. R. Khaitov
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 24, Iss 2, Pp 157-171 (2024)
INTRODUCTION. Small interfering RNAs (siRNAs) are among the most promising types of therapeutic nucleic acids aiming at the inhibition of pathogenetically relevant gene expression through the RNA interference mechanism. However, the limited bioavaila
Externí odkaz:
https://doaj.org/article/eb2d2fbfb84c4e88a2f8d5a7cea9133d
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 2, Pp 132-154 (2024)
INTRODUCTION. Pharmacogenetic (PGx) testing plays a significant role in predicting the risk of adverse drug reactions (ADRs) associated with valproic acid (VPA) products, which are among the most prescribed medicinal products in neurology and psychia
Externí odkaz:
https://doaj.org/article/32c6ea0e49e5483e87a4e211daaad892
Autor:
Joshua Smyth, Julien Godet, Anisa Choudhary, Anubrata Das, Georgios V. Gkoutos, Animesh Acharjee
Publikováno v:
Cancer Medicine, Vol 13, Iss 22, Pp n/a-n/a (2024)
Background Colorectal cancer (CRC) is any cancer that starts in the colon or the rectum and presents a significant health concern. It is the third most diagnosed and the second deadliest cancer, with an estimated 153,020 new cases and 52,550 deaths i
Externí odkaz:
https://doaj.org/article/ae0b3dee84b0443bbf1a444d53c6e3d0