Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Perry Palmedo"'
Autor:
Perry Palmedo, Christian Dallago, Thomas A. Hopf, Chan Kang, John Ingraham, Adam J. Riesselman, Benjamin Schubert, Agnes Toth-Petroczy, Eli J. Draizen, Kelly P Brock, Sophia Mersmann, Debora S. Marks, Anna G. Green, Charlotta P I Schärfe, Robert L. Sheridan, Chris Sander
Publikováno v:
Bioinformatics
Summary Coevolutionary sequence analysis has become a commonly used technique for de novo prediction of the structure and function of proteins, RNA, and protein complexes. We present the EVcouplings framework, a fully integrated open-source applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1e433a672704c5a7c0a39c116f77d9
https://mediatum.ub.tum.de/doc/1538420/document.pdf
https://mediatum.ub.tum.de/doc/1538420/document.pdf
Autor:
Sevin Turcan, Kan Lin, Agnes Viale, Perry Palmedo, Radhika Raheja, Rameen Beroukhim, Shasha Meng, I-Li Tan, Yongxing Gong, Steven E. Schumacher, Timothy A. Chan, Travis I. Zack, Ellen Hukkelhoven, Selvaraju Veeriah, Luc G. T. Morris
Publikováno v:
Nature Genetics. 46:588-594
Coordinate control of different classes of cyclins is fundamentally important for cell cycle regulation and tumor suppression, yet the underlying mechanisms are incompletely understood. Here we show that the PARK2 tumor suppressor mediates this coord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04aeda2ecfc155f73a40e6404986ae99
https://doi.org/10.1038/ng.2981
https://doi.org/10.1038/ng.2981
Autor:
Thomas A. Hopf, John Ingraham, Bonnie Berger, Debora S. Marks, Perry Palmedo, Agnes Toth-Petroczy, Chris Sander
Publikováno v:
PMC
Protein flexibility ranges from simple hinge movements to functional disorder. Around half of all human proteins contain apparently disordered regions with little 3D or functional information, and many of these proteins are associated with disease. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0b776af131b027a1f821c8a446213b
http://hdl.handle.net/1721.1/115426
http://hdl.handle.net/1721.1/115426
Publikováno v:
Cell systems
Elsevier
Elsevier
While genes are defined by sequence, in biological systems a protein's function is largely determined by its three-dimensional structure. Evolutionary information embedded within multiple sequence alignments provides a rich source of data for inferri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775a42a037b7662e1001eebb10117d06
https://doi.org/10.1016/j.cels.2017.11.014
https://doi.org/10.1016/j.cels.2017.11.014