Chronic lymphocytic leukemia presence impairs antigen-specific CD8+ T-cell responses through epigenetic reprogramming towards short-lived effectors

Autor: Anne Martens, Inga Kavazovic, Su Min Pack, Ramon Arens, Aldo Jongejan, Perry Moerland, Eric Eldering, gerritje windt van der, felix wensveen, Fleur Peters, Arnon Kater

T-cell dysregulation in chronic lymphocytic leukemia (CLL) associates with low response rates to autologous T cell-based therapies. How CLL affects antigen-specific T-cell responses remains largely unknown. We investigated (epi)genetic and functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22a73bbd03eb23452ac01bd0f26760c3
https://doi.org/10.21203/rs.3.rs-1829072/v1

Method for all-positive optical multilayer perceptrons

Autor: Saxena, I., Fiesler, E., Perry Moerland

Publikováno v: STARTPAGE=448;ENDPAGE=451;TITLE=Proceedings of the 1996 3rd IEEE International Conference on Electronics, Circuits, and Systems, ICECS. Part 2 (of 2)
Scopus-Elsevier

The most promising approaches for optical neural networks are based on intensity encoding. However, a serious drawback of intensity encoding is the lack of negative values and optical subtraction, which are essential for rendering neural networks use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::39e1ab83161f0de1e7ab1b5b9d98e3d1
https://pure.amc.nl/en/publications/method-for-allpositive-optical-multilayer-perceptrons(bc3e8b2b-34d8-47a4-b4dc-f42152525a5a).html

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