Hypothalamic mTORC2 is essential for metabolic health and longevity.

Autor: Chellappa K; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Brinkman JA; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Mukherjee S; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Morrison M; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Alotaibi MI; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Endocrinology and Reproductive Physiology Graduate Training Program, University of Wisconsin-Madison, Madison, WI, USA., Carbajal KA; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Alhadeff AL; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Perron IJ; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Yao R; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Purdy CS; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., DeFelice DM; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wakai MH; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Tomasiewicz J; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Lin A; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Department of Dairy Science, University of Wisconsin-Madison, Madison, WI, USA., Meyer E; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Department of Dairy Science, University of Wisconsin-Madison, Madison, WI, USA., Peng Y; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Arriola Apelo SI; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Department of Dairy Science, University of Wisconsin-Madison, Madison, WI, USA., Puglielli L; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Betley JN; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA., Paschos GK; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Baur JA; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lamming DW; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Endocrinology and Reproductive Physiology Graduate Training Program, University of Wisconsin-Madison, Madison, WI, USA.

Publikováno v: Aging cell [Aging Cell] 2019 Oct; Vol. 18 (5), pp. e13014. Date of Electronic Publication: 2019 Aug 01.

Dietary challenges differentially affect activity and sleep/wake behavior in mus musculus: Isolating independent associations with diet/energy balance and body weight.

Autor: Perron IJ; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Keenan BT; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Chellappa K; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Lahens NF; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Yohn NL; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Shockley KR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America., Pack AI; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Veasey SC; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Publikováno v: PloS one [PLoS One] 2018 May 10; Vol. 13 (5), pp. e0196743. Date of Electronic Publication: 2018 May 10 (Print Publication: 2018).

Normal sleep requires the astrocyte brain-type fatty acid binding protein FABP7.

Autor: Gerstner JR; Department of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.; Sleep and Performance Research Center, Washington State University, Spokane, WA 99210, USA., Perron IJ; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Riedy SM; Department of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.; Sleep and Performance Research Center, Washington State University, Spokane, WA 99210, USA., Yoshikawa T; RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan., Kadotani H; Department of Sleep and Behavioral Sciences, Shiga University of Medical Science, Otsu City, Shiga 520-2192, Japan., Owada Y; Department of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan., Van Dongen HPA; Department of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.; Sleep and Performance Research Center, Washington State University, Spokane, WA 99210, USA., Galante RJ; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Dickinson K; Department of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA., Yin JCP; Department of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA., Pack AI; Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Frank MG; Department of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA.; Sleep and Performance Research Center, Washington State University, Spokane, WA 99210, USA.

Publikováno v: Science advances [Sci Adv] 2017 Apr 05; Vol. 3 (4), pp. e1602663. Date of Electronic Publication: 2017 Apr 05 (Print Publication: 2017).

BMAL1 controls the diurnal rhythm and set point for electrical seizure threshold in mice.

Autor: Gerstner JR; Department of Neuroscience, University of Pennsylvania Philadelphia, PA, USA ; Center for Sleep and Circadian Neurobiology, University of Pennsylvania Philadelphia, PA, USA., Smith GG; Department of Psychiatry, University of Pennsylvania Philadelphia, PA, USA ; Research Service, Department of Veterans Affairs Medical Center Coatesville, PA, USA., Lenz O; Center for Sleep and Circadian Neurobiology, University of Pennsylvania Philadelphia, PA, USA., Perron IJ; Department of Neuroscience, University of Pennsylvania Philadelphia, PA, USA ; Center for Sleep and Circadian Neurobiology, University of Pennsylvania Philadelphia, PA, USA., Buono RJ; Department of Biomedical Sciences, Cooper Medical School of Rowan University Camden, NJ, USA., Ferraro TN; Department of Psychiatry, University of Pennsylvania Philadelphia, PA, USA ; Research Service, Department of Veterans Affairs Medical Center Coatesville, PA, USA ; Department of Biomedical Sciences, Cooper Medical School of Rowan University Camden, NJ, USA.

Publikováno v: Frontiers in systems neuroscience [Front Syst Neurosci] 2014 Jun 26; Vol. 8, pp. 121. Date of Electronic Publication: 2014 Jun 26 (Print Publication: 2014).

The effect of glycomimetic functionalized collagen on peripheral nerve repair.

Autor: Masand SN; Department of Biomedical Engineering, Rutgers, The State University of New Jersey, 599 Taylor Road, Piscataway, NJ 08854, USA., Chen J, Perron IJ, Hammerling BC, Loers G, Schachner M, Shreiber DI

Publikováno v: Biomaterials [Biomaterials] 2012 Nov; Vol. 33 (33), pp. 8353-62. Date of Electronic Publication: 2012 Aug 20.