Update on Pediatric Cancer Surveillance Recommendations for Patients with Neurofibromatosis Type 1, Noonan Syndrome, CBL Syndrome, Costello Syndrome, and Related RASopathies.

Autor: Perrino MR; Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee., Das A; Division of Paediatric Haematology and Oncology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Scollon SR; Department of Pediatrics, Texas Children's Cancer and Hematology Center, Baylor College of Medicine, Houston, Texas., Mitchell SG; Department of Pediatrics, Children's Healthcare of Atlanta, Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, Georgia., Greer MC; Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada., Yohe ME; Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Hansford JR; Michael Rice Centre for Hematology and Oncology, Women's and Children's Hospital, Adelaide, South Australia, Australia.; South Australia Health and Medical Research Institute, Adelaide, South Australia, Australia.; South Australia ImmunoGENomics Cancer Institute, University of Adelaide, Adelaide, South Australia, Australia., Kalish JM; Division of Genetics and Center for Childhood Cancer Research Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Schultz KAP; Cancer and Blood Disorders, Children's Minnesota, Minneapolis, Minnesota., MacFarland SP; Division of Oncology, Department of Pediatrics, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania., Kohlmann WK; VA Medical Center, National TeleOncology Clinical Cancer Genetics Service, Durham, North Carolina.; University of Utah Huntsman Cancer Institute, Salt Lake City, Utah., Lupo PJ; Division of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas., Maxwell KN; Division of Oncology, Department of Pediatrics, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.; Medicine Service, Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania., Pfister SM; Division Pediatric Neurooncology, Hopp Children´s Cancer Center Heidelberg (KiTZ), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg University Hospital and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Weksberg R; Division of Clinical and Metabolic Genetics, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada., Michaeli O; Division of Hematology and Oncology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Jongmans MCJ; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Tomlinson GE; Division of Hematology-Oncology, Department of Pediatrics, Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas., Brzezinski J; Division of Paediatric Haematology and Oncology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Tabori U; Division of Paediatric Haematology and Oncology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ney GM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland., Gripp KW; Division of Medical Genetics, Nemours Children's Hospital, Wilmington, Delaware., Gross AM; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Widemann BC; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Stewart DR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland., Woodward ER; University of Manchester and Manchester Centre for Genomic Medicine, Manchester, United Kingdom., Kratz CP; Hannover Medical School, Hannover, Germany.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Nov 01; Vol. 30 (21), pp. 4834-4843.

Concomitant Wilms tumor and autosomal dominant polycystic kidney disease.

Autor: Fleming AM; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Gehle DB; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Perrino MR; Division of Cancer Predisposition, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Graetz DE; Solid Tumor Division, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Bissler JJ; Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Pediatric Nephrology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA., McCarville B; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Krasin MJ; Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Brennan RC; Department of Pediatric Hematology & Oncology, Logan Health, Kalispell, Montana, USA., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Yang W; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Sapkota Y; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Hudson MM; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Cancer Survivorship, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Davidoff AM; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Green DM; Division of Cancer Survivorship, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Murphy AJ; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Oct; Vol. 71 (10), pp. e31230. Date of Electronic Publication: 2024 Jul 31.

Atypical teratoid/rhabdoid tumour-TYR subtype arising in the setting of germline ring chromosome 22: An uncommon form of tumour predisposition.

Autor: Lee JC; Department of Pathology, Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Tran QT; Department of Pathology, Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., McGee RB; Department of Oncology, Division of Cancer Predisposition, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Perrino MR; Department of Oncology, Division of Cancer Predisposition, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Upadhyaya SA; Department of Pediatrics and Communicable Diseases, C. S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA., Hanzlik EM; Department of Pediatrics, Division of Neuro-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Pytel N; Department of Pediatrics, Division of Neuro-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Carroll AJ; Department of Genetics, University of Alabama, Birmingham, Alabama, USA., Orisme W; Department of Pathology, Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Eldomery M; Department of Pathology, Molecular Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Wang L; Department of Pathology, Molecular Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Blackburn PR; Department of Pathology, Molecular Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Furtado LV; Department of Pathology, Molecular Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Viaene AN; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Luo M; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Kalish JM; Division of Human Genetics and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Departments of Genetics and Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Pinto SN; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Bag AK; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Orr BA; Department of Pathology, Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

Publikováno v: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2024 Apr; Vol. 50 (2), pp. e12971.

Germline genomic findings in children and young adults with melanocytic tumors.

Autor: Nagel MB; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA.; Department of Pediatrics, UT Southwestern Medical Center Dallas, Dallas, Texas, USA., Perrino MR; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA., Nuccio R; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA.; Regina Nuccio current address: Concert Genetics, Nashville, TN, USA., Blake AK; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA., Harrison L; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA., Nichols KE; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA., Pappo AS; Department of Oncology, St. Jude Children's Hospital Memphis, Memphis, Tennessee, USA.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2023 Jul; Vol. 70 (7), pp. e30361. Date of Electronic Publication: 2023 Apr 19.

WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth.

Autor: Thomson CS; Department of Pharmacology and Systems Physiology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Pundavela J; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Perrino MR; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Coover RA; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, High Point, NC, USA., Choi K; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Chaney KE; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Rizvi TA; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Largaespada DA; Department of Genetics, Cell Biology, and Development, College of Biological Sciences, University of Minnesota, Minneapolis, MN, USA., Ratner N; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Nancy.ratner@cchmc.org.; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA. Nancy.ratner@cchmc.org.

Publikováno v: Oncogene [Oncogene] 2021 Jun; Vol. 40 (24), pp. 4229-4241. Date of Electronic Publication: 2021 Jun 02.