Zobrazeno 1 - 10
of 729
pro vyhledávání: '"Peroxiredoxin 1"'
Autor:
Junghyung Park, Jinyoung Won, Eunyeoung Yang, Jincheol Seo, Jiyeon Cho, Jung Bae Seong, Hyeon-Gu Yeo, Keonwoo Kim, Yu Gyeong Kim, Minji Kim, Chang-Yeop Jeon, Kyung Seob Lim, Dong-Seok Lee, Youngjeon Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Oxidative stress plays an essential role in the progression of Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced abnormal brain insulin signaling and oxidative stress play crucia
Externí odkaz:
https://doaj.org/article/9b87bdf82c684c9584fa4b5278bb4b3a
Autor:
Ping Yu, Tanwei Gu, Yueyang Rao, Weimin Liang, Xi Zhang, Huanguo Jiang, Jindi Lu, Jianglian She, Jianmin Guo, Wei Yang, Yonghong Liu, Yingfeng Tu, Lan Tang, Xuefeng Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3232-3250 (2024)
Insufficient therapeutic strategies for acute kidney injury (AKI) necessitate precision therapy targeting its pathogenesis. This study reveals the new mechanism of the marine-derived anti-AKI agent, piericidin glycoside S14, targeting peroxiredoxin 1
Externí odkaz:
https://doaj.org/article/d25b34968aac42819ebddcb13d0f09a5
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The purpose of this study was to investigate the photoprotection effect of peroxiredoxin 1 (PRDX1) protein in ultraviolet B (UVB) irradiation-induced damage of retinal pigment epithelium (RPE) and its possible molecular mechanism.
Externí odkaz:
https://doaj.org/article/b053c37df6574df3a80dd33709f2f139
Autor:
Lingyu Li, Jing Li, Yunping Lu, Wenjing Li, Jing Yang, Min Wang, Congcong Miao, Zhenchuan Tian, Min Zhang, Xiaofei Tang
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31227- (2024)
Peroxiredoxin 1 (Prx1) is an antioxidant protein that may promote the carcinogenesis in oral leukoplakia (OLK). To investigate the effect of Prx1 on the oral mucosal epithelium of OLK, we generated a Prx1 conditional knockout (cKO) mouse model. The m
Externí odkaz:
https://doaj.org/article/5ccc2e804a834d1fa93f909f240d75bc
Autor:
Yang Yuan, Hongchen Tan, Huailong Chen, Jiawen Zhang, Fei Shi, Mingshan Wang, Gaofeng Zhang, Haipeng Wang, Rui Dong
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 11, Pp 1305-1312 (2023)
Objective(s): Cerebral ischemia/reperfusion (I/R) injury inevitably aggravates the initial cerebral tissue damage following a stroke. Peroxiredoxin 1 (Prdx1) is a representative protein of the endogenous antioxidant enzyme family that regulates sever
Externí odkaz:
https://doaj.org/article/dca91c9452e24fd69c55a74c81d1e639
Akademický článek
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Autor:
Amandine Moretton, Savvas Kourtis, Antoni Gañez Zapater, Chiara Calabrò, Maria Lorena Espinar Calvo, Frédéric Fontaine, Evangelia Darai, Etna Abad Cortel, Samuel Block, Laura Pascual‐Reguant, Natalia Pardo‐Lorente, Ritobrata Ghose, Matthew G Vander Heiden, Ana Janic, André C Müller, Joanna I Loizou, Sara Sdelci
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 7, Pp 1-27 (2023)
Abstract While cellular metabolism impacts the DNA damage response, a systematic understanding of the metabolic requirements that are crucial for DNA damage repair has yet to be achieved. Here, we investigate the metabolic enzymes and processes that
Externí odkaz:
https://doaj.org/article/99959834b32e4fb5a1f4c0a860ce238d
Autor:
Hu-Nan Sun, Chen-Xi Ren, Dong Hun Lee, Wei-Hao Wang, Xiao-Yu Guo, Ying-Ying Hao, Xiao-Ming Wang, Hui-Na Zhang, Wan-Qiu Xiao, Nan Li, Jie Cong, Ying-Hao Han, Taeho Kwon
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-19 (2023)
Abstract Background Pulmonary fibrosis is a major category of end-stage changes in lung diseases, characterized by lung epithelial cell damage, proliferation of fibroblasts, and accumulation of extracellular matrix. Peroxiredoxin 1 (PRDX1), a member
Externí odkaz:
https://doaj.org/article/d810c93285744648968c4496f846ec4f
Autor:
Larissa Anastacio da Costa Carvalho, Isabella Harumi Yonehara Noma, Adriana Hiromi Uehara, Ádamo Davi Diógenes Siena, Luciana Harumi Osaki, Mateus Prates Mori, Nadja Cristhina de Souza Pinto, Vanessa Morais Freitas, Wilson Araújo Silva Junior, Keiran S. M. Smalley, Silvya Stuchi Maria-Engler
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 555 (2024)
Microenvironment and transcriptional plasticity generate subpopulations within the tumor, and the use of BRAF inhibitors (BRAFis) contributes to the rise and selection of resistant clones. We stochastically isolated subpopulations (C1, C2, and C3) fr
Externí odkaz:
https://doaj.org/article/f3a02e5a37c140b9b79b9aff14cb175d
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.