Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Perola O. Magalhães"'
Autor:
Kellen C. R. Andrade, Rildo A. Fernandes, Danilo Batista Pinho, Marcela M. de Freitas, Edivaldo Ximenes Ferreira Filho, Adalberto Pessoa, João Inácio Silva, Perola O. Magalhães
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The enzyme L-asparaginase (L-ASNase) is used in the treatment of Acute Lymphoblastic Leukemia. The preparations of this enzyme for clinical use are derived from bacterial sources and its use is associated with serious adverse reactions. In t
Externí odkaz:
https://doaj.org/article/0ddc797cf0064351ac855f8c8ee61da4
Publikováno v:
Frontiers in Fungal Biology, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/b3ad06d7af844789a8ddfdd3af2f72e6
Autor:
Camilo Di Giulio, Juan Manuel Gonzalez Guzman, Joao Victor Dutra Gomes, Young Hae Choi, Pérola O. Magalhães, Yris M. Fonseca-Bazzo, Damaris Silveira, Omar Estrada
Publikováno v:
Molecules, Vol 28, Iss 11, p 4256 (2023)
Esquamosan, a new furofuran lignan, has been isolated by bio-guided assays from the methanolic extract of the leaves of Annona squamosa L., and its structure was elucidated by spectroscopic methods. Esquamosan inhibited the rat aortic ring contractio
Externí odkaz:
https://doaj.org/article/08dad04f1af04da3889654c8de735ce6
Autor:
Marcela Freitas, Paula Souza, Mauricio Homem-de-Mello, Yris M. Fonseca-Bazzo, Damaris Silveira, Edivaldo X. Ferreira Filho, Adalberto Pessoa Junior, Dipak Sarker, David Timson, João Inácio, Pérola O. Magalhães
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 746 (2022)
L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential amino acid synthesized by normal cells, but not by neoplastic cells. Adver
Externí odkaz:
https://doaj.org/article/816ee450df474fa1a5fe9db259dd5a1e
Autor:
Marcela Freitas, Paula Souza, Samuel Cardoso, Kellen Cruvinel, Letícia Santos Abrunhosa, Edivaldo X. Ferreira Filho, João Inácio, Danilo Batista Pinho, Adalberto Pessoa, Pérola O. Magalhães
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1268 (2021)
l-asparaginase is an enzyme used as treatment for acute lymphoblastic leukemia (ALL) due to its ability to hydrolyze l-asparagine, an essential amino acid synthesized by normal cells unlike neoplastic cells. The adverse effects of l-asparaginase form
Externí odkaz:
https://doaj.org/article/875b7c24860944ec99755b1ab1697b19
Autor:
Thaís Barros, Larissa Brumano, Marcela Freitas, Adalberto Pessoa, Nádia Parachin, Pérola O. Magalhães
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 14 (2020)
Since 1961, L-asparaginase has been used to treat patients with acute lymphocytic leukemia. It rapidly depletes the plasma asparagine and deprives the blood cells of this circulating amino acid, essential for the metabolic cycles of cells. In the sea
Externí odkaz:
https://doaj.org/article/3bc8da91748646968a22a6c0a6c19f86