Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pernille Seiffert"'
Autor:
Raul Araya-Secchi, Katrine Bugge, Pernille Seiffert, Amalie Petry, Gitte W Haxholm, Kresten Lindorff-Larsen, Stine Falsig Pedersen, Lise Arleth, Birthe B Kragelund
Publikováno v:
eLife, Vol 12 (2023)
Class 1 cytokine receptors transmit signals through the membrane by a single transmembrane helix to an intrinsically disordered cytoplasmic domain that lacks kinase activity. While specific binding to phosphoinositides has been reported for the prola
Externí odkaz:
https://doaj.org/article/dfbd0e7ab7e54119a7d5a8fe4a1c6660
Autor:
Yash Chhabra, Pernille Seiffert, Rachel S. Gormal, Manon Vullings, Christine Mei Mei Lee, Tristan P. Wallis, Farhad Dehkhoda, Sowmya Indrakumar, Nina L. Jacobsen, Kresten Lindorff-Larsen, Nela Durisic, Michael J. Waters, Frédéric A. Meunier, Birthe B. Kragelund, Andrew J. Brooks
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112490- (2023)
Summary: Growth hormone (GH) acts via JAK2 and LYN to regulate growth, metabolism, and neural function. However, the relationship between these tyrosine kinases remains enigmatic. Through an interdisciplinary approach combining cell biology, structur
Externí odkaz:
https://doaj.org/article/f0578a76c2ca4997a9b58592d72fb7fd
Autor:
Pernille Seiffert, Katrine Bugge, Mads Nygaard, Gitte W. Haxholm, Jacob H. Martinsen, Martin N. Pedersen, Lise Arleth, Wouter Boomsma, Birthe B. Kragelund
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-30 (2020)
Abstract Background Class 1 cytokine receptors (C1CRs) are single-pass transmembrane proteins responsible for transmitting signals between the outside and the inside of cells. Remarkably, they orchestrate key biological processes such as proliferatio
Externí odkaz:
https://doaj.org/article/da80cd82ba2c4e498f5a4570acf51ca8
Autor:
Francesco Pesce, Estella A. Newcombe, Pernille Seiffert, Emil E. Tranchant, Johan G. Olsen, Christy R. Grace, Birthe B. Kragelund, Kresten Lindorff-Larsen
Publikováno v:
Pesce, F, Newcombe, E A, Seiffert, P, Tranchant, E E, Olsen, J G, Grace, C R, Kragelund, B B & Lindorff-Larsen, K 2023, ' Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins ', Biophysical Journal, vol. 122, no. 2, pp. 310-321 . https://doi.org/10.1016/j.bpj.2022.12.013
Diffusion measurements by pulsed-field gradient NMR and fluorescence correlation spectroscopy can be used to probe the hydrodynamic radius of proteins, which contains information about the overall dimension of a protein in solution. The comparison of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219b34702011c2aa700b4e1102721e6
https://curis.ku.dk/ws/files/334258562/2022.06.11.495732v2.full.pdf
https://curis.ku.dk/ws/files/334258562/2022.06.11.495732v2.full.pdf
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2141
Intrinsically disordered proteins (IDPs) have no single, fixed tertiary structure, yet they take on many vital functions in biology. In recent years, considerable effort has been put into the structural characterization of their conformational ensemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dace0d80d0888259693927e4ad9f1b33
https://pubmed.ncbi.nlm.nih.gov/32696358
https://pubmed.ncbi.nlm.nih.gov/32696358
Autor:
Wouter Boomsma, Gitte W. Haxholm, Pernille Seiffert, Katrine Bugge, Jacob H. Martinsen, Martin Nors Pedersen, Birthe B. Kragelund, Lise Arleth, Mads Nygaard
Publikováno v:
Seiffert, P, Bugge, K, Nygaard, M, Haxholm, G W, Martinsen, J H, Pedersen, M N, Arleth, L, Boomsma, W & Kragelund, B B 2020, ' Orchestration of signaling by structural disorder in class 1 cytokine receptors ', Cell Communication and Signaling, vol. 18, no. 1, 132 . https://doi.org/10.1186/s12964-020-00626-6
Cell communication and signaling 18(1), 1-30 (2020). doi:10.1186/s12964-020-00626-6
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-30 (2020)
Cell Communication and Signaling : CCS
Cell communication and signaling 18(1), 1-30 (2020). doi:10.1186/s12964-020-00626-6
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-30 (2020)
Cell Communication and Signaling : CCS
Cell communication and signaling 18(1), 1-30 (2020). doi:10.1186/s12964-020-00626-6
Background:Class 1 cytokine receptors (C1CRs) are single-pass transmembrane proteins responsible for transmitting signals between the outside and the inside of c
Background:Class 1 cytokine receptors (C1CRs) are single-pass transmembrane proteins responsible for transmitting signals between the outside and the inside of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f28389f0c225061a45f73311a81fbc
https://doi.org/10.21203/rs.3.rs-23462/v2
https://doi.org/10.21203/rs.3.rs-23462/v2
Publikováno v:
Methods in Molecular Biology ISBN: 9781071605233
Intrinsically disordered proteins (IDPs) have no single, fixed tertiary structure, yet they take on many vital functions in biology. In recent years, considerable effort has been put into the structural characterization of their conformational ensemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419b6c730ba14b5a13b186aed1d4cd20
https://doi.org/10.1007/978-1-0716-0524-0_9
https://doi.org/10.1007/978-1-0716-0524-0_9