Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pernilla Wikstrom"'
Autor:
Maria Nilsson, Christina Hägglöf, Peter Hammarsten, Elin Thysell, Pär Stattin, Lars Egevad, Torvald Granfors, Emma Jernberg, Pernilla Wikstrom, Sofia Halin Bergström, Anders Bergh
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140985 (2015)
Lysyl oxidase (LOX) has been shown to both promote and suppress tumor progression, but its role in prostate cancer is largely unknown. LOX immunoreactivity was scored in prostate tumor epithelium, tumor stroma and in the tumor-adjacent non-malignant
Externí odkaz:
https://doaj.org/article/a3abacd574194e6c88dd8d66a3ef94f0
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Prostate cancer (PC) is a heterogenous multifocal disease ranging from indolent to lethal states. For improved treatment-stratification, reliable approaches are needed to faithfully differentiate between high- and low-risk tumors
Externí odkaz:
https://doaj.org/article/34429af7d043452f982ccd3e04f70b89
Autor:
Petra Henning, Ali Kassem, Anna Westerlund, Pernilla Lundberg, Cecilia Engdahl, Vikte Lionikaite, Pernilla Wikström, Jianyao Wu, Lei Li, Catharina Lindholm, Pedro P. C. de Souza, Sofia Movérare-Skrtic, Ulf H. Lerner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
It is well established that inflammatory processes in the vicinity of bone often induce osteoclast formation and bone resorption. Effects of inflammatory processes on bone formation are less studied. Therefore, we investigated the effect of locally i
Externí odkaz:
https://doaj.org/article/336269047b1142138c0c06e32ee49a03
Autor:
Johan Wänman, Kasim Abul-Kasim, Julius Semenas, Elin Thysell, Anders Bergh, Pernilla Wikström, Sead Crnalic
Publikováno v:
European Urology Open Science, Vol 48, Iss , Pp 44-53 (2023)
Background: Prostate cancer spinal bone metastases can have a radiographic profile that mimics multiple myeloma. Objective: To analyse the presence and prognostic value of myeloma-like prostate cancer bone metastases and its relation to known clinica
Externí odkaz:
https://doaj.org/article/663aaae897454f51885b906ab47fb96b
Autor:
Elin Thysell, Linda Köhn, Julius Semenas, Helena Järemo, Eva Freyhult, Marie Lundholm, Camilla Thellenberg Karlsson, Jan‐Erik Damber, Anders Widmark, Sead Crnalic, Andreas Josefsson, Karin Welén, Rolf J. A. Nilsson, Anders Bergh, Pernilla Wikström
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 846-859 (2022)
To improve treatment of metastatic prostate cancer, the biology of metastases needs to be understood. We recently described three subtypes of prostate cancer bone metastases (MetA‐C), based on differential gene expression. The aim of this study was
Externí odkaz:
https://doaj.org/article/65f5c75dc7eb47b6a1f8e39de3159faa
Autor:
Helena Järemo, Julius Semenas, Sofia Halin Bergström, Marie Lundholm, Elin Thysell, Anders Widmark, Sead Crnalic, Erik Bovinder Ylitalo, Anders Bergh, Maria Brattsand, Pernilla Wikström
Publikováno v:
Cancers, Vol 15, Iss 9, p 2437 (2023)
MicroRNAs (miRNAs) are aberrantly expressed in prostate cancer (PC), but comprehensive knowledge about their levels and function in metastatic PC is lacking. Here, we explored the differential expression of miRNA profiles during PC progression to bon
Externí odkaz:
https://doaj.org/article/5b71d4befa3b4001a2c54c67f306993b
Autor:
Ilona Dudka, Elin Thysell, Kristina Lundquist, Henrik Antti, Diego Iglesias-Gato, Amilcar Flores-Morales, Anders Bergh, Pernilla Wikström, Gerhard Gröbner
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Prostate cancer (PC) can display very heterogeneous phenotypes ranging from indolent asymptomatic to aggressive lethal forms. Understanding how these PC subtypes vary in their striving for energy and anabolic molecules is of funda
Externí odkaz:
https://doaj.org/article/080966912352427d9768afd0ab60ea79
Autor:
Pernilla Wikström, Sofia Halin Bergström, Andreas Josefsson, Julius Semenas, Annika Nordstrand, Elin Thysell, Sead Crnalic, Anders Widmark, Camilla Thellenberg Karlsson, Anders Bergh
Publikováno v:
Cancers, Vol 14, Iss 21, p 5195 (2022)
Prostate cancer (PC) bone metastases can be divided into transcriptomic subtypes, by us termed MetA-C. The MetB subtype, constituting about 20% of the cases, is characterized by high cell cycle activity, low androgen receptor (AR) activity, and a lim
Externí odkaz:
https://doaj.org/article/57313bd012bd4bec967c15338bdb3f2f
Autor:
Elin Thysell, Linda Vidman, Erik Bovinder Ylitalo, Emma Jernberg, Sead Crnalic, Diego Iglesias‐Gato, Amilcar Flores‐Morales, Pär Stattin, Lars Egevad, Anders Widmark, Patrik Rydén, Anders Bergh, Pernilla Wikström
Publikováno v:
Molecular Oncology, Vol 13, Iss 8, Pp 1763-1777 (2019)
Bone metastasis is the lethal end‐stage of prostate cancer (PC), but the biology of bone metastases is poorly understood. The overall aim of this study was therefore to explore molecular variability in PC bone metastases of potential importance for
Externí odkaz:
https://doaj.org/article/0bd093ff3c7f4e92a8ab6f49ee9111c2
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13023 (2021)
The human kallikrein-related peptidase 4 (KLK4) and the transcribed pseudogene KLKP1 are reported to be highly expressed in the prostate. When trying to clone transcripts of KLKP1, we partly failed. Instead, we identified an androgen-regulated transc
Externí odkaz:
https://doaj.org/article/c7cae9b20e7c46cdae52f8f41e08f62e