Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Pernilla Glader"'
Publikováno v:
International Journal of COPD, Vol 2011, Iss default, Pp 83-88 (2011)
Sven Larsson1, Anita Nordenson1, Pernilla Glader1, Shigemi Yoshihara2, Anders Lindén1, Frode Slinde31Department of Internal Medicine/Respiratory Medicine and Allergology, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden;
Externí odkaz:
https://doaj.org/article/043ed5e032504865805a690d2773bd43
Autor:
Margaretha E Smith, Steven Bozinovski, Carina Malmhäll, Margareta Sjöstrand, Pernilla Glader, Per Venge, Pieter S Hiemstra, Gary P Anderson, Anders Lindén, Ingemar Qvarfordt
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75032 (2013)
We tested the hypothesis that activation of the innate immune response induces an imbalance in the proteolytic homeostasis in the peripheral airways of healthy subjects, towards excess serine or gelatinase proteinase activity. During bronchoscopy, 18
Externí odkaz:
https://doaj.org/article/097a50799582498f901ee40875231daf
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49723 (2012)
It has previously been shown that nano-meter sized vesicles (30-100 nm), exosomes, secreted by antigen presenting cells can induce T cell responses thus showing the potential of exosomes to be used as immunological tools. Additionally, activated CD3
Externí odkaz:
https://doaj.org/article/23272c598e454ae18983c1399ff85839
Autor:
Eva Lamm Bergström, Fredrik Wågberg, Christian Tyrchan, Anders Lundqvist, Ulf Andersson, Xiao-Hong Zhou, Robert Ronn, Linda Swedin, Grigorios Nikitidis, Fanyi Jiang, Victoria Ullah, Antonios Nikitidis, Petra Johannesson, Eva Björkstrand, Hui-Fang Chang, Theresa Andreasson, Lena Ripa, Magnus Munck af Rosenschöld, Pernilla Glader, Anna Pettersen, Britta Bonn, Margareta Ek, Andrew M. Davis, Euan Gordon, Helena Käck, Dave Chapman, Mattias Rohman, Anna Malmberg
Publikováno v:
Journal of Medicinal Chemistry. 62:7769-7787
While bronchodilators and inhaled corticosteroids are the mainstay of asthma treatment, up to 50% of asthmatics remain uncontrolled. Many studies show that the cysteinyl leukotriene cascade remains highly activated in some asthmatics, even those on h
Autor:
Magnus, Munck Af Rosenschöld, Petra, Johannesson, Antonios, Nikitidis, Christian, Tyrchan, Hui-Fang, Chang, Robert, Rönn, Dave, Chapman, Victoria, Ullah, Grigorios, Nikitidis, Pernilla, Glader, Helena, Käck, Britta, Bonn, Fredrik, Wågberg, Eva, Björkstrand, Ulf, Andersson, Linda, Swedin, Mattias, Rohman, Theresa, Andreasson, Eva Lamm, Bergström, Fanyi, Jiang, Xiao-Hong, Zhou, Anders J, Lundqvist, Anna, Malmberg, Margareta, Ek, Euan, Gordon, Anna, Pettersen, Lena, Ripa, Andrew M, Davis
Publikováno v:
Journal of medicinal chemistry. 62(17)
While bronchodilators and inhaled corticosteroids are the mainstay of asthma treatment, up to 50% of asthmatics remain uncontrolled. Many studies show that the cysteinyl leukotriene cascade remains highly activated in some asthmatics, even those on h
Autor:
J Franzén, Jacob Leander, A Berton, Joanne Betts, Christina Keen, Cecilia Kristensson, Bengt Larsson, M Albayaty, A. Aurell Holmberg, Z Santisteban, Pernilla Glader, Tove Hegelund-Myrbäck, Alexandra Jauhiainen
Publikováno v:
Asthma: from diagnosis to treatment.
AZD9898 is an oral small molecule inhibitor of LTC4 synthase (LTC4s) developed for the treatment of asthma driven by cysteinyl leukotrienes (CysLTs). It is expected to inhibit the downstream production of leukotrienes LTC4, LTD4 and LTE4, which are i
Autor:
Linda Swedin, Johanna Vinblad, Theresa Andreasson, Pernilla Glader, Fanyi Jiang, Henrik Bergquist, Mattias Rohman, Eva Lamm Bergström, Britt-Marie Wissing, Corinne Hamblet, Magnus Munck af Rosenschöld, Anders Lundqvist, Louise Hafsten, Fredrik Wågberg, Kristensson Lisbeth, Andrew M. Davis, Ann Aurell Holmberg
Publikováno v:
Airway Pharmacology and Treatment.
Rational: AZD9898 is a small molecule inhibitor of leukotriene C4 synthase (LTC4S) in development for oral treatment of leukotriene driven asthma. AZD9898 is expected to inhibit the downstream production of CysLTs but, unlike the 5-LO inhibitor Zileu
Autor:
Ingemar Qvarfordt, Pernilla Glader, Anders Lindén, Lena Palmberg, Barbro Dahlén, Kjell Larsson, Bettina Levänen, Bo Billing
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Bettina Levänen,1 Pernilla Glader,2 Barbro Dahlén,3,4 Bo Billing,4 Ingemar Qvarfordt,2 Lena Palmberg,1 Kjell Larsson,1 Anders Lindén1,2,4 1Unit for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 2D
Publikováno v:
Inflammation Research. 62:561-569
Interleukin (IL)-22 is important for mucosal host defense. Whereas previous studies focus on lymphocytes as sources of IL-22, we determined whether IL-22 is produced by inflammatory cells in the lungs other than T-lymphocytes during the activation of
Autor:
Kaj A. Svedberg, Medya Shikhagaie, Pernilla Glader, Jonas S. Erjefält, Cecilia Andersson, Michiko Mori, Claes-Göran Löfdahl, Anders Bergqvist
Publikováno v:
Thorax; 68(6), pp 521-531 (2013)
Rationale The alveolar pathology in chronic obstructive pulmonary disease (COPD) involves antigen-driven immune events. However, the induction sites of alveolar adaptive immune responses have remained poorly investigated. Objectives To explore the hy