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Phosphorylation of the translation initiation factor eIF-2alpha downregulates protein synthesis by sequestering the guanylate exchange factor eIF-2B. The importance of this regulation has been demonstrated in the context of stress and virally induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f7c9b283cf18c53608ff1da5970ec61
https://europepmc.org/articles/PMC6148258/
https://europepmc.org/articles/PMC6148258/