Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

Autor: Florence Massiera, Perla Saint-Marc, Josiane Seydoux, Takahiko Murata, Takuya Kobayashi, Shuh Narumiya, Philippe Guesnet, Ez-Zoubir Amri, Raymond Negrel, Gérard Ailhaud

Publikováno v: Journal of Lipid Research, Vol 44, Iss 2, Pp 271-279 (2003)

High fat intake is associated with fat mass gain through fatty acid activation of peroxisome proliferator-activated receptors δ and γ, which promote adipogenesis. We show herein that, compared to a combination of specific agonists to both receptors

Externí odkaz: https://doaj.org/article/47992fd004a24cb58505437401a59729

Prostacyclin IP receptor up-regulates the early expression of C/EBPβ and C/EBPδ in preadipose cells

Autor: Nathalie Belmonte, Perla Saint-Marc, Jérôme Aubert, Raymond Negrel, Gérard Ailhaud, Christian Dani

Publikováno v: Molecular and Cellular Endocrinology. 160:149-156

Prostacyclin (PGI(2)) and its stable analogue carbacyclin (cPGI(2)) are known to trigger the protein kinase A pathway after binding to the cell surface IP receptor and to promote or enhance terminal differentiation of adipose precursor cells to adipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e676dbfb3e2029831856bab5b4961df3
https://doi.org/10.1016/s0303-7207(99)00210-5

Angiotensinogen, angiotensin II and adipose tissue development

Autor: Gérard Ailhaud, Akiyoshi Fukamizu, Florence Massiera, Raymond Negrel, Michèle Teboul, Perla Saint-Marc

Publikováno v: Europe PubMed Central

Adipose tissue is an important source of angiotensinogen (AGT). Recent evidence shows that a local renin-angiotensinogen system (RAS) is present in human adipose tissue and may act as a distinct system from plasma RAS. In obese patients, the involvem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8549f0d3b51f32c1a08e21ec550fe24
https://doi.org/10.1038/sj.ijo.0801501

Adipocyte differentiation of multipotent cells established from human adipose tissue

Autor: Christian Elabd, Anne Guezennec, Joelle Guesnet, Julien Astier, Gérard Ailhaud, Anne-Marie Rodriguez, Christian Dani, Ez-Zoubir Amri, Cécile Vernochet, Perla Saint-Marc, Frédéric Delteil

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2004, 315 (2), pp.255-63. ⟨10.1016/j.bbrc.2004.01.053⟩

International audience; In this study multipotent adipose-derived stem cells isolated from human adipose tissue (hMADS cells) were shown to differentiate into adipose cells in serum-free, chemically defined medium. During the differentiation process,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fb80c9ef90dd477e2f36a3be1b1f02
https://pubmed.ncbi.nlm.nih.gov/14766202

Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

Autor: Ez-Zoubir Amri, Raymond Negrel, Shuh Narumiya, Josiane Seydoux, Takuya Kobayashi, Takahiko Murata, Perla Saint-Marc, Florence Massiera, Philippe Guesnet, Gérard Ailhaud

Publikováno v: Journal of Lipid Research 2 (44), 271-9. (2003)
Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2003, 44 (2), pp.271-9. ⟨10.1194/jlr.M200346-JLR200⟩
The Journal of Lipid Research
The Journal of Lipid Research, 2003, 44 (2), pp.271-9. ⟨10.1194/jlr.M200346-JLR200⟩
Journal of Lipid Research, Vol 44, Iss 2, Pp 271-279 (2003)

International audience; High fat intake is associated with fat mass gain through fatty acid activation of peroxisome proliferator-activated receptors delta and gamma, which promote adipogenesis. We show herein that, compared to a combination of speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea3675966be477d5ee429fffe37186a
http://prodinra.inra.fr/record/250415