Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Perla M. del Rio Estrada"'
Autor:
Spiros Georgakis, Michail Orfanakis, Cloe Brenna, Simon Burgermeister, Perla M. Del Rio Estrada, Mauricio González-Navarro, Fernanda Torres-Ruiz, Gustavo Reyes-Terán, Santiago Avila-Rios, Yara Andrea Luna-Villalobos, Oliver Y. Chén, Giuseppe Pantaleo, Richard A. Koup, Constantinos Petrovas
Publikováno v:
Vaccines, Vol 12, Iss 8, p 912 (2024)
Follicular helper CD4hi T cells (TFH) are a major cellular pool for the maintenance of the HIV reservoir. Therefore, the delineation of the follicular (F)/germinal center (GC) immune landscape will significantly advance our understanding of HIV patho
Externí odkaz:
https://doaj.org/article/e34491b2bac84b12a559ae4ab2f0b6f8
Autor:
Eva Bednarski, Perla M. Del Rio Estrada, Justin DaSilva, Celia Boukadida, Fengwen Zhang, Yara A. Luna-Villalobos, Ximena Rodríguez-Rangel, Elvira Pitén-Isidro, Edgar Luna-García, Dafne Díaz Rivera, Dulce M. López-Sánchez, Daniela Tapia-Trejo, Maribel Soto-Nava, Myriam Astorga-Castañeda, José O. Martínez-Moreno, Guadalupe S. Urbina-Granados, José A. Jiménez-Jacinto, Francisco J. Serna Alvarado, Yerania E. Enriquez-López, Oliva López-Arellano, Gustavo Reyes-Teran, Paul D. Bieniasz, Santiago Avila-Rios, Theodora Hatziioannou
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Global population immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is accumulating through heterogeneous combinations of infection and vaccination. Vaccine distribution in low- and middle-income countries has been var
Externí odkaz:
https://doaj.org/article/f3466aec2fa541f5b3b52f21336f628f
Autor:
Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A. Ostrowski, Perla M. Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W. David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The intact proviral DNA assay quantifies the genomically intact HIV reservoir, but assay failure due to HIV-1 polymorphism has been observed. Here, the authors report a 28% failure rate in a cohort of people with HIV-1, and note within-host HIV-1 div
Externí odkaz:
https://doaj.org/article/2f1b4a3b13f745078fbaecf15223c1ef
Autor:
Eirini Moysi, Perla M. Del Rio Estrada, Fernanda Torres-Ruiz, Gustavo Reyes-Terán, Richard A. Koup, Constantinos Petrovas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD4 T cells are key mediators of adaptive immune responses during infection and vaccination. Within secondary lymphoid organs, helper CD4 T cells, particularly those residing in germinal centers known as follicular helper T cells (Tfh), provide criti
Externí odkaz:
https://doaj.org/article/8cd40c3a2dd847ffad1a9580da401543
Autor:
Vincent H. Wu, Christopher L. Nobles, Leticia Kuri-Cervantes, Kevin McCormick, John K. Everett, Son Nguyen, Perla M. del Rio Estrada, Mauricio González-Navarro, Fernanda Torres-Ruiz, Santiago Ávila-Ríos, Gustavo Reyes-Terán, Frederic D. Bushman, Michael R. Betts
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
The integration of HIV DNA into the host genome contributes to lifelong infection in most individuals. Few studies have examined integration in lymphoid tissue, where HIV predominantly persists before and after antiretroviral treatment (ART). Of part
Externí odkaz:
https://doaj.org/article/96269c12f3904621b09eb17564db2182
Autor:
Vincent H. Wu, Jayme M. L. Nordin, Son Nguyen, Jaimy Joy, Felicity Mampe, Perla M. del Rio Estrada, Fernanda Torres-Ruiz, Mauricio González-Navarro, Yara Andrea Luna-Villalobos, Santiago Ávila-Ríos, Gustavo Reyes-Terán, Pablo Tebas, Luis J. Montaner, Katharine J. Bar, Laura A. Vella, Michael R. Betts
Publikováno v:
Nature Immunology. 24:359-370
Understanding the complexity of the long-lived HIV reservoir during antiretroviral therapy (ART) remains a considerable impediment in research towards a cure for HIV. To address this, we developed a single-cell strategy to precisely define the unpert
Autor:
Natalie N. Kinloch, Yanqin Ren, Winiffer Conce Alberto, Winnie Dong, Szu Han Huang, Andrew Wilson, Talia M. Mota, Don Kikby, Perla M. Del Rio Estrada, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss , Pp 9- (2019)
Externí odkaz:
https://doaj.org/article/4336d136d6684ee6b561decec6b68455
Autor:
Morgan A. Reuter, Perla M. Del Rio Estrada, Marcus Buggert, Constantinos Petrovas, Sara Ferrando-Martinez, Son Nguyen, Alberto Sada Japp, Yuria Ablanedo-Terrazas, Amaranta Rivero-Arrieta, Leticia Kuri-Cervantes, Heidi M. Gunzelman, Emma Gostick, David A. Price, Richard A. Koup, Ali Naji, David H. Canaday, Gustavo Reyes-Terán, Michael R. Betts
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3458-3470 (2017)
Summary: Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8+ T cells play a critical role in control of HIV, but their functional attributes in lymph nodes (LNs) remain unclear. Here, we show that memory,
Externí odkaz:
https://doaj.org/article/6bc44c6e41074190a760d0bb474a3be4
Autor:
Sadia Samer, Ankita Chowdhury, Tomas Raul Wiche Salinas, Perla M. Del Rio Estrada, Morgan Reuter, Gregory Tharp, Steven Bosinger, Barbara Cervasi, James Auger, Kiran Gill, Yuria Ablanedo-Terrazas, Gustavo Reyes-Teran, Jacob D. Estes, Michael R. Betts, Guido Silvestri, Mirko Paiardini
Publikováno v:
Journal of Virology.
The HIV reservoir is largely composed of latently infected memory CD4 + T cells that persist during antiretroviral therapy and constitute a major barrier toward HIV eradication. In particular, CD4 + T follicular helper cells have been demonstrated as
Autor:
Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A. Ostrowski, Perla M. Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W. David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/d63b13d33e68408f9ca3dd6ccf322f0f