Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Perisynaptic space"'
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The calyx of Held is a giant nerve terminal mediating high-frequency excitatory input to principal cells of the medial nucleus of the trapezoid body (MNTB). MNTB principal neurons are enwrapped by densely organized extracellular matrix structures, kn
Publikováno v:
Frontiers in cellular neuroscience 15, 637784 (2021). doi:10.3389/fncel.2021.637784
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
High-affinity, Na+-dependent glutamate transporters are the primary means by which synaptically released glutamate is removed from the extracellular space. They restrict the spread of glutamate from the synaptic cleft into the perisynaptic space and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63d72fc648ab67ced2a92d0b88b9ef4
Publikováno v:
ACS Chem Neurosci
Recent optical observations of dopamine at axon terminals and kinetic modeling of evoked dopamine responses measured by fast scan cyclic voltammetry (FSCV) support local restriction of dopamine diffusion at synaptic release sites. Yet, how this diffu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8776ec62a8c00232f4845e4c057f2c
https://europepmc.org/articles/PMC9668542/
https://europepmc.org/articles/PMC9668542/
Autor:
Achut P. Silwal, H. Peter Lu
Publikováno v:
ACS chemical neuroscience. 9(12)
Dopamine (DA) is the catecholamine neurotransmitter which interacts with dopamine receptors (DARs) to generate dopaminergic signals in the nervous system. Dopamine transporter (DAT) interacts with DA to maintain DA's homeostasis in synaptic and peris
Autor:
Mandy Sonntag, Carsten Jäger, Constanze I. Seidenbecher, Johannes Seeger, Renato Frischknecht, Rudolf Rübsamen, Russell T. Matthews, Maren Blosa, Markus Morawski, Solveig Weigel, Thomas Arendt
Publikováno v:
The Journal of Physiology. 593:4341-4360
Key points The proteoglycan brevican is a major component of the extracellular matrix of perineuronal nets and is highly enriched in the perisynaptic space suggesting a role for synaptic transmission. We have introduced the calyx of Held in the audit
Autor:
Joseph H. Neale
Publikováno v:
Journal of Neurochemistry. 119:891-895
Although N-Acetylaspartylglutamate (NAAG) was first reported in the mid 1960s to be present in the mammalian brain and spinal cord at mM concentrations, the critical experiments that established this peptide as a neurotransmitter emerged several deca
Publikováno v:
The Journal of Cell Biology
Spatial competition between glial cells causes them to partition neuromuscular junctions into discrete domains within a synapse.
Schwann cells (SCs), the glial cells of the peripheral nervous system, cover synaptic terminals, allowing them to mo
Schwann cells (SCs), the glial cells of the peripheral nervous system, cover synaptic terminals, allowing them to mo
Autor:
P. Rod Dunbar, Natalie Lorenz, Anna E. S. Brooks, Daniel Verdon, Chun-Jen J. Chen, Claudia Mansell, Catherine E. Angel, Nigel P. Birch, Evert Jan Loef
Publikováno v:
Journal of leukocyte biology. 97(4)
Contact between T cells and APCs and activation of an effective immune response trigger cellular polarization and the formation of a structured interface known as the immunological synapse. Interactions across the synapse and secretion of T cell and
Autor:
Dmitri A. Rusakov, Dimitri M. Kullmann
Publikováno v:
The Journal of Neuroscience. 18:3158-3170
Fast excitatory synapses are generally thought to act as private communication channels between presynaptic and postsynaptic neurons. Some recent findings, however, suggest that glutamate may diffuse out of the synaptic cleft and bind to several subt
Publikováno v:
Journal of Visualized Experiments.
Our project identified GFP labeled glial structures at the developing larval fly neuromuscular synapse. To look at development of live glial-nerve-muscle synapses, we developed a larval tissue preparation that had features of live intact larvae, but