Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Periplocymarin"'
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2491-2497 (2022)
Periplocymarin (PPM), a cardiac glycoside isolated from Cortex periplocae, has a strong anti-tumor effect against various cancer cells. However, cardiotoxicity and rapid metabolism hinder its clinical applications. In this study, small molecule prodr
Externí odkaz:
https://doaj.org/article/3d2628d399824ae2be01ec975d7e32b5
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Doxorubicin-driven cardiotoxicity could result in dilated cardiomyopathy and heart failure (HF). Previously, we showed that periplocymarin exerted a cardiotonic role by promoting calcium influx and attenuating myocardial fibrosis induced by isoproter
Externí odkaz:
https://doaj.org/article/91bf8d7834924ee9a355a2e3052e47dc
Autor:
Yi Cheng, Guiying Wang, Lianmei Zhao, Suli Dai, Jing Han, Xuhua Hu, Chaoxi Zhou, Feifei Wang, Hongqing Ma, Baokun Li, Zesong Meng
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Colorectal cancer (CRC) is one of the most common cancers worldwide, and approximately one-third of CRC patients present with metastatic disease. Periplocymarin (PPM), a cardiac glycoside isolated from Periploca sepium, is a latent anticancer compoun
Externí odkaz:
https://doaj.org/article/a7c05fd1c0b24ce483a85065f5353ac9
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111562- (2021)
Periplocymarin is an effective component of Periplocae Cortex, which was wildly used as an ingredient in Traditional Chinese Medicine. Our group previously reported that periplocymarin exerted cardiotonic role via promoting calcium influx. However, i
Externí odkaz:
https://doaj.org/article/88bc53dc35cb4f10a1c0734dfc52ffa9
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Periplocymarin, which belongs to cardiac glycosides, is an effective component extracted from Periplocae Cortex. However, its cardiovascular effects remain unidentified. In the present study, injection of periplocymarin (5 mg/kg) through external jug
Externí odkaz:
https://doaj.org/article/262a014ba6444d3688e07c9115721212
Autor:
Huiyun Zhang, Wenqian Xu, Emmanuel Omari-Siaw, Yingkun Liu, Baoding Chen, Deyu Chen, Jiangnan Yu, Ximing Xu
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1170-1178 (2017)
Periplocymarin (PPM), a cardiac glycoside, has a narrow therapeutic index, poor tumor selectivity and severe cardiovascular toxicity which hinder its wide clinical applications in cancer treatment. Herein, we report novel redox-responsive prodrug-nan
Externí odkaz:
https://doaj.org/article/9eae6fd52f444e13a885bc892436d1e8
Autor:
Chen Jian Xia, Wei Qing Tao, Chen Fan, Wu Hao, Fu Ying Qing, Wu Zhi Gui, Dai Xin Hua, Ye Yi, Yan You Yi, Liao Lin Chuan
Publikováno v:
Journal of Forensic Science and Medicine, Vol 3, Iss 4, Pp 191-196 (2017)
A simple, rapid and sensitive liquid chromatography with tandem mass spectrometry method for the determination of periplocymarin in human blood and urine was developed. The digoxin-d3 was used as an internal standard. Periplocymarin and digoxin-d3 (I
Externí odkaz:
https://doaj.org/article/3bf0145ede5b4a0aa9d073d4b6ac18ba
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine
Doxorubicin-driven cardiotoxicity could result in dilated cardiomyopathy and heart failure (HF). Previously, we showed that periplocymarin exerted a cardiotonic role by promoting calcium influx and attenuating myocardial fibrosis induced by isoproter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b03a22a9d10d1c96b668690ed9e094
https://www.frontiersin.org/articles/10.3389/fcvm.2021.732554/full
https://www.frontiersin.org/articles/10.3389/fcvm.2021.732554/full
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.