Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Peripheral tolerance induction"'
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 100(3)
Abstract Regulatory T cells (Tregs) suppress immune responses and thus contribute to immune homeostasis. On the downside, Tregs also limit immune responses against tumors promoting the progression of cancer. Among the many mechanisms implied in Treg-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f81d85f4a2bc9cb99a27de49b81a208
https://pubmed.ncbi.nlm.nih.gov/34423375
https://pubmed.ncbi.nlm.nih.gov/34423375
Publikováno v:
Blood Reviews, 32(4), 326. Churchill Livingstone
At first sight the bleeding disorder hemophilia A seems to have little in common with immune disorders, but immunology research intersects with other disciplines including hematology. Nowadays, the most important complication in the treatment of hemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aece037f3e3819d138ce313635c16d5
https://dspace.library.uu.nl/handle/1874/374213
https://dspace.library.uu.nl/handle/1874/374213
Publikováno v:
Immunology. 145:171-181
Antigen-specific immunotherapy aims to selectively restore tolerance to innocuous antigens in cases of autoimmune or allergic disease, without the need for general immune suppression. Although the principle of antigen-specific immunotherapy was disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4c4eef6344f5247fd7c293a48ef411
https://doi.org/10.1111/imm.12458
https://doi.org/10.1111/imm.12458
Technologies that induce antigen-specific immune tolerance by mimicking naturally occurring mechanisms have the potential to revolutionize the treatment of many immune-mediated pathologies such as autoimmunity, allograft rejection, and allergy. The i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43c7004edab7e40ffa9a0f8b199b438
https://europepmc.org/articles/PMC5582017/
https://europepmc.org/articles/PMC5582017/
Autor:
Kunal H. Bhatt, Raymond J. Steptoe, Ryan Galea, James W. Wells, Rajeev Rudraraju, Jeremy F. Brooks, Ji-Won Jung
Publikováno v:
Stem Cell Research & Therapy
Background Application of genetically modified hematopoietic stem cells is increasingly mooted as a clinically relevant approach to protein replacement therapy, immune tolerance induction or conditions where both outcomes may be helpful. Hematopoieti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4246ee94d8adeab2acd600dcfd7c811
https://doi.org/10.1186/s13287-017-0508-3
https://doi.org/10.1186/s13287-017-0508-3
Publikováno v:
Transplantation. 102:S694
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87641289129042fe9fe4cd374d00f80
https://doi.org/10.1097/01.tp.0000543648.15059.a4
https://doi.org/10.1097/01.tp.0000543648.15059.a4
Autor:
Jean Davoust, Pascal Chappert, Philippe Rameau, Mélanie Lalfer, Marylène Leboeuf, Sabine Desbois, Olivier Danos, Roland S. Liblau, David-Alexandre Gross
Publikováno v:
European Journal of Immunology. 40:339-350
Foxp3(+) Treg are crucial for the maintenance of self-tolerance and have been shown to control CD8(+) T-cell effector functions. In addition, Treg are thought to control the priming of CD8(+) T cells, which recognize the same antigens as Treg. Taking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73c7ba0e7c95bb1fef799f451076d7b
https://doi.org/10.1002/eji.200839107
https://doi.org/10.1002/eji.200839107
Autor:
Gareth Denyer, Andreas Strasser, William R. Heath, Gayle M. Davey, Gordon K. Smyth, Ian A. Parish, Torsten Juelich, Sudha Rao
Publikováno v:
Blood. 113:4575-4585
Peripheral tolerance induction is critical for the maintenance of self-tolerance and can be mediated by immunoregulatory T cells or by direct induction of T-cell anergy or deletion. Although the molecular processes underlying anergy have been extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5922043c2cafcf872c72d235163b9fe
https://doi.org/10.1182/blood-2008-10-185223
https://doi.org/10.1182/blood-2008-10-185223
Autor:
B. Bohle
Publikováno v:
Allergologie. 31:326-332
More than 70% of birch pollen-allergic patients develop hypersensitivity reactions to certain foods which are mainly caused by IgE antibodies specific for the major birch pollen allergen, Bet v 1, which crossreact with structurally related proteins i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb96e6fad32b28442ccd2762329d8240
https://doi.org/10.5414/alp31326
https://doi.org/10.5414/alp31326
Autor:
Danielle M. Turley, Stephen D. Miller
Publikováno v:
The Journal of Immunology. 178:2212-2220
MHC class II (MHC II)-restricted T cell responses are a common driving force of autoimmune disease. Accordingly, numerous therapeutic strategies target CD4+ T cells with the hope of attenuating autoimmune responses and restoring self-tolerance. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819821db6e8cb6673d662a5f1366ddc8
https://doi.org/10.4049/jimmunol.178.4.2212
https://doi.org/10.4049/jimmunol.178.4.2212