Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Perinur Bozaykut"'
Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Increasing chronological age is the greatest risk factor for human diseases. Cellular senescence (CS), which is characterized by permanent cell-cycle arrest, has recently emerged as a fundamental mechanism in developing aging-related pathologies. Dur
Externí odkaz:
https://doaj.org/article/ce76ce6c7b634f2686442b4d1a125333
Autor:
Nurcan Inci, Erdogan Oguzhan Akyildiz, Abdullah Alper Bulbul, Eda Tahir Turanli, Emel Akgun, Ahmet Tarik Baykal, Faruk Colak, Perinur Bozaykut
Publikováno v:
Biology, Vol 11, Iss 9, p 1253 (2022)
The blind mole rat (BMR), a long-living subterranean rodent, is an exceptional model for both aging and cancer research since they do not display age-related phenotypes or tumor formation. The Janus kinase–signal transducer and activator of transcr
Externí odkaz:
https://doaj.org/article/db8b61363b3142278a351ff80a76f73c
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 323-332 (2016)
Nrf2 pathway has been known to be protective against cancer progression however recent studies have revealed that the antioxidant activity of Nrf2 contributes to chemotherapy resistance. For many years, hyperthermia has been used as an additional the
Externí odkaz:
https://doaj.org/article/5bf7c9efffee40dc9314279fa99ef887
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 732-738 (2014)
Atherosclerosis and its complications are major causes of death all over the world. One of the major risks of atherosclerosis is hypercholesterolemia. During atherosclerosis, oxidized low density lipoprotein (oxLDL) regulates CD36-mediated activation
Externí odkaz:
https://doaj.org/article/e38231dc0a524b06a87082a62bb16052
Publikováno v:
BioFactors. 46:653-664
Formation of atherosclerotic plaques, called atherogenesis, is a complex process affected by genetic and environmental factors. It was proposed that endoplasmic reticulum (ER) stress is an important factor in the pathogenesis of atherosclerosis and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3abe3da63b47fcb2cde4c81a8b9cdcc
https://doi.org/10.1002/biof.1635
https://doi.org/10.1002/biof.1635
Autor:
Perinur Bozaykut Eker
Publikováno v:
Volume: 12, Issue: 3 553-557
Acıbadem Üniversitesi Sağlık Bilimleri Dergisi
Acıbadem Üniversitesi Sağlık Bilimleri Dergisi
Purpose: Naked mole-rats (NMR, Heterocephalus glaber) have extreme resistance to cancer although they are known as the longest-living rodent with their 30-year maximum lifespan. Therefore, NMRs have rapidly emerged as a natural model for biomedical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb79799d595d5820797f4bb8ffc5523
https://dergipark.org.tr/tr/pub/acusaglik/issue/62213/864377
https://dergipark.org.tr/tr/pub/acusaglik/issue/62213/864377
Autor:
Perinur Bozaykut
Objectives Some organisms are long-lived and naturally resistant to cancer such as naked mole-rats (NMRs). Studies have shown that these animals can better tolerate stress due to mechanisms, such as upregulation of antioxidant pathways and improved p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce3d8fa5e0e60639dd40dc62d1af2f9
https://aperta.ulakbim.gov.tr/record/233192
https://aperta.ulakbim.gov.tr/record/233192
Autor:
Eker, Perinur Bozaykut
Publikováno v:
Acibadem Saglik Bilimleri Dergisi; Jul2021, Vol. 12 Issue 3, p553-557, 5p
Autor:
Nesrin Kartal Ozer, Perinur Bozaykut, Esra Ozaltin, Elif Kaga, Jonas Bergquist, Asli Ece, Erdi Sozen, Betul Karademir Yilmaz
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others, proteasomal system is an efficient protein turnover complex to avoid aggregation of oxidized prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90731849070c0019dfd229a9cbe41722
https://hdl.handle.net/11424/242962
https://hdl.handle.net/11424/242962
Autor:
Perinur Bozaykut
Publikováno v:
Oxidative Stress in Heart Diseases ISBN: 9789811382727
Aging, which is associated with several undesirable processes, is a complex phenomenon. Aging mechanisms are not fully comprehended yet, however, diseased and aged cells are correlated with accumulation of senescent cells. Various studies have reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::671a822d8b0588c36d21c38d866bede9
https://doi.org/10.1007/978-981-13-8273-4_10
https://doi.org/10.1007/978-981-13-8273-4_10