Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Perforin-2"'
Autor:
Choi, Kwang-Min a, Cho, Dong-Hee a, Joo, Min-Soo a, Choi, Hye-Sung b, Kim, Myoung Sug b, Han, Hyun-Ja b, Cho, Mi Young b, Hwang, Seong Don b, Kim, Do-Hyung c, ∗∗, Park, Chan-Il a, ∗
Publikováno v:
In Fish and Shellfish Immunology December 2020 107 Part B:511-518
Autor:
Kattel, Sharma a, b, Bhatt, Hardik a, Xu, Shirley a, Gurung, Sharda a, Pokharel, Saraswati c, Sharma, Umesh C. a, ⁎
Publikováno v:
In Resuscitation October 2020 155:180-188
Autor:
Leidy C. Merselis, Shirley Y. Jiang, Stanley F. Nelson, Hane Lee, Kavitha K. Prabaker, Jennifer L. Baker, George P. Munson, Manish J. Butte
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IntroductionMacrophage expressed gene 1 (MPEG1) is highly expressed in macrophages and other phagocytes. The gene encodes a bactericidal pore-forming protein, dubbed Perforin-2. Structural-, animal-, and cell-based studies have established that perfo
Externí odkaz:
https://doaj.org/article/5fee46864fd14ebb8ec62479cb57f5e6
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The invertebrate innate immune system is surprisingly complex, yet our knowledge is limited to a few select model systems. One understudied group is the phylum Cnidaria (corals, sea anemones, etc.). Cnidarians are the sister group to Bilateria and by
Externí odkaz:
https://doaj.org/article/b2eceb693b134cab8dfba59a15ed95df
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Gamma delta (GD) T cells are an unconventional T cell type present in both the epidermis and the dermis of human skin. They are critical to regulating skin inflammation, wound healing, and anti-microbial defense. Similar to CD8+ cytotoxic T cells exp
Externí odkaz:
https://doaj.org/article/eb7bb34e7c714f69a92343290cfa8e98
Autor:
Daniela Frasca, Alain Diaz, Maria Romero, Thomas Vazquez, Natasa Strbo, Laura Romero, Ryan M. McCormack, Eckhard R. Podack, Bonnie B. Blomberg
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Perforin-2 (P2) is a pore-forming protein with cytotoxic activity against intracellular bacterial pathogens. P2 knockout (P2KO) mice are unable to control infections and die from normally non-lethal bacterial infections. Here we show that P2KO mice a
Externí odkaz:
https://doaj.org/article/04f3f6cd06b94afa81df56baafe32650
Autor:
Eckhard Podack, George P Munson
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Immunology is the science of biological warfare between the defenses of our immune systems and offensive pathogenic microbes and cancers. Over the course of his scientific career Eckhard R. Podack made several seminal discoveries that elucidated key
Externí odkaz:
https://doaj.org/article/58de428e39494e63a54f290dde753fc5
Akademický článek
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Publikováno v:
eLife, Vol 4 (2015)
Perforin-2 (MPEG1) is an effector of the innate immune system that limits the proliferation and spread of medically relevant Gram-negative, -positive, and acid fast bacteria. We show here that a cullin-RING E3 ubiquitin ligase (CRL) complex containin
Externí odkaz:
https://doaj.org/article/a3638339c956499aab1fcba23fdd1db0
Publikováno v:
In Methods in Enzymology 2021 649:189-217