Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Perez-Benito L"'
Autor:
Medrano Sandonas L; Department of Physics and Materials Science, University of Luxembourg, L-1511, Luxembourg City, Luxembourg. leonardo.medrano@tu-dresden.de.; Institute for Materials Science and Max Bergmann Center of Biomaterials, TU Dresden, 01062, Dresden, Germany. leonardo.medrano@tu-dresden.de., Van Rompaey D; Drug Discovery Data Sciences (D3S), Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium. dvanrom1@its.jnj.com., Fallani A; Department of Physics and Materials Science, University of Luxembourg, L-1511, Luxembourg City, Luxembourg.; Drug Discovery Data Sciences (D3S), Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Hilfiker M; Department of Physics and Materials Science, University of Luxembourg, L-1511, Luxembourg City, Luxembourg., Hahn D; Computational Chemistry, Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Perez-Benito L; Computational Chemistry, Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Verhoeven J; Drug Discovery Data Sciences (D3S), Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Tresadern G; Computational Chemistry, Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Kurt Wegner J; Drug Discovery Data Sciences (D3S), Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium.; Drug Discovery Data Sciences (D3S), Johnson & Johnson Innovative Medicine, 301 Binney Street, MA 02142, Cambridge, USA., Ceulemans H; Drug Discovery Data Sciences (D3S), Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium., Tkatchenko A; Department of Physics and Materials Science, University of Luxembourg, L-1511, Luxembourg City, Luxembourg. alexandre.tkatchenko@uni.lu.
Publikováno v:
Scientific data [Sci Data] 2024 Jul 07; Vol. 11 (1), pp. 742. Date of Electronic Publication: 2024 Jul 07.
Autor:
Yu X; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA. xyu6@its.jnj.com., Matico RE; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA., Miller R; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA., Chauhan D; Johnson & Johnson Innovation Medicine, J&J Interventional Oncology, Beerse, Belgium., Van Schoubroeck B; Johnson & Johnson Innovation Medicine, J&J Interventional Oncology, Beerse, Belgium., Grauwen K; Johnson & Johnson Innovation Medicine, J&J Interventional Oncology, Beerse, Belgium., Suarez J; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA., Pietrak B; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA., Haloi N; Department of Applied Physics, Swedish e-Science Research Center, KTH Royal Institute of Technology, Stockholm, Sweden., Yin Y; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA., Tresadern GJ; Johnson & Johnson Innovation Medicine, Discovery Sciences, Beerse, Belgium., Perez-Benito L; Johnson & Johnson Innovation Medicine, Discovery Sciences, Beerse, Belgium., Lindahl E; Department of Biochemistry and Biophysics, Science for Life Laboratory, Stockholm University, Stockholm, Sweden., Bottelbergs A; Johnson & Johnson Innovation Medicine, Discovery Sciences, Beerse, Belgium., Oehlrich D; Johnson & Johnson Innovation Medicine, Discovery Sciences, Beerse, Belgium., Van Opdenbosch N; Johnson & Johnson Innovation Medicine, J&J Interventional Oncology, Beerse, Belgium., Sharma S; Johnson & Johnson Innovation Medicine, Spring House, PA, 19044, USA.
Publikováno v:
Nature communications [Nat Commun] 2024 Feb 07; Vol. 15 (1), pp. 1164. Date of Electronic Publication: 2024 Feb 07.
Autor:
Serneels L; Department of Neuroscience, KU Leuven, Leuven, Belgium; Center for Brain and Disease Research, VIB, Leuven, Belgium., Narlawar R; Department of Neuroscience, KU Leuven, Leuven, Belgium; Center for Brain and Disease Research, VIB, Leuven, Belgium; Deparment of Discovery Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Perez-Benito L; Deparment of Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Municoy M; Nostrum Biodiscovery, Barcelona, Spain., Guallar V; Life Sciences Department, Barcelona Supercomputing Center, Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., T'Syen D; Department of Neuroscience, KU Leuven, Leuven, Belgium., Dewilde M; Department of Neuroscience, KU Leuven, Leuven, Belgium., Bischoff F; Deparment of Discovery Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Fraiponts E; Charles River Laboratories, Beerse, Belgium., Tresadern G; Deparment of Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Roevens PWM; Campus Strategy & Partnerships, Janssen Pharmaceutica NV, Beerse, Belgium., Gijsen HJM; Deparment of Discovery Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., De Strooper B; Department of Neuroscience, KU Leuven, Leuven, Belgium; Dementia Research Institute, University College London, London, UK. Electronic address: bart.destrooper@kuleuven.be.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2023 Jun; Vol. 299 (6), pp. 104794. Date of Electronic Publication: 2023 May 09.
Reduction of stress responses in honey bees by synthetic ligands targeting an allatostatin receptor.
Autor:
Sánchez-Morales A; Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain., Gigoux V; Centre de Recherches en Cancérologie de Toulouse (CRCT), INSERM Unité Mixte de Recherche UMR-1037, CNRS Equipe de Recherche Labellisée ERL5294, Université de Toulouse, Toulouse, France., Matsoukas MT; Unitat de Bioestadística, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain., Perez-Benito L; Unitat de Bioestadística, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain.; Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Turnhoutseweg 30, B-2340, Beerse, Belgium., Fourmy D; Centre de Recherches en Cancérologie de Toulouse (CRCT), INSERM Unité Mixte de Recherche UMR-1037, CNRS Equipe de Recherche Labellisée ERL5294, Université de Toulouse, Toulouse, France., Alibes R; Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain., Busqué F; Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain. Felix.Busque@uab.cat., Cordomí A; Unitat de Bioestadística, Universitat Autònoma de Barcelona, Bellaterra, 08193, Barcelona, Spain. arnau.cordoni@esci.upf.edu.; Bioinformatics, ESCI-Universitat Pompeu Fabra, Passeig Pujades 1, 08003, Barcelona, Spain. arnau.cordoni@esci.upf.edu., Devaud JM; Centre de Recherches Sur La Cognition Animale (CRCA), Centre de Biologie Intégrative, 9 (CBI), Université de Toulouse, CNRS, Toulouse, France. jean-marc.devaud@univ-tlse3.fr.
Publikováno v:
Scientific reports [Sci Rep] 2022 Oct 06; Vol. 12 (1), pp. 16760. Date of Electronic Publication: 2022 Oct 06.
Akademický článek
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Autor:
Doornbos, M.L.J., Perez-Benito, L., Tresadern, G., Mulder, T., Biesmans, I., Trabanco, A.A., Cid, M.J., Lavreysen, H., IJzerman, A.P., Heitman, L.H.
Background and PurposeAllosteric modulation of the mGlu2 receptor is a potential strategy for treatment of various neurological and psychiatric disorders. Here, we describe the in vitro characterization of the mGlu2 positive allosteric modulator (PAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f4d5e7776b81de9ca885d7a993ebf64a
http://hdl.handle.net/1887/3199664
http://hdl.handle.net/1887/3199664
Autor:
Bolik, Kim-Viktoria1 (AUTHOR), Hellmann, Jan2 (AUTHOR), Maschauer, Simone1 (AUTHOR), Neu, Eduard2,3 (AUTHOR), Einsiedel, Jürgen2 (AUTHOR), Riss, Patrick4 (AUTHOR), Vogg, Nora5 (AUTHOR), König, Jörg3,5 (AUTHOR), Fromm, Martin F.3,5 (AUTHOR), Hübner, Harald2 (AUTHOR), Gmeiner, Peter2,3 (AUTHOR), Prante, Olaf1,3 (AUTHOR) olaf.prante@uk-erlangen.de
Publikováno v:
EJNMMI Research. 9/4/2024, Vol. 14 Issue 1, p1-16. 16p.
Akademický článek
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Autor:
Deflorian F; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG United Kingdom., Perez-Benito L; Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Turnhoutseweg 30, B-2340 Beerse, Belgium., Lenselink EB; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden 2300, RA, The Netherlands., Congreve M; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG United Kingdom., van Vlijmen HWT; Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Turnhoutseweg 30, B-2340 Beerse, Belgium., Mason JS; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG United Kingdom., Graaf C; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG United Kingdom., Tresadern G; Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V., Turnhoutseweg 30, B-2340 Beerse, Belgium.
Publikováno v:
Journal of chemical information and modeling [J Chem Inf Model] 2020 Nov 23; Vol. 60 (11), pp. 5563-5579. Date of Electronic Publication: 2020 Jul 06.
Autor:
Serneels L; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., T'Syen D; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., Perez-Benito L; Computational Chemistry, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Theys T; Department of Neurosciences, Research Group Experimental Neurosurgery and Neuroanatomy, KU Leuven, Leuven, Belgium., Holt MG; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., De Strooper B; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium. bart.destrooper@kuleuven.vib.be.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium. bart.destrooper@kuleuven.vib.be.; UK Dementia Research Institute at UCL, University College London, London, UK. bart.destrooper@kuleuven.vib.be.
Publikováno v:
Molecular neurodegeneration [Mol Neurodegener] 2020 Oct 19; Vol. 15 (1), pp. 60. Date of Electronic Publication: 2020 Oct 19.