Pathways of airway oxidant formation by house dust mite allergens and viral RNA converge through myosin motors, pannexons and Toll-like receptor 4

Autor: Zhang, Jihui, Chen, Jie, Mangat, Shannon C., Perera Baruhupolage, Chathuri, Garrod, David R., Robinson, Clive

Publikováno v: Zhang, J, Chen, J, Mangat, S C, Perera Baruhupolage, C, Garrod, D R & Robinson, C 2018, ' Pathways of airway oxidant formation by house dust mite allergens and viral RNA converge through myosin motors, pannexons and Toll-like receptor 4 ', Immunity Inflammation and Disease, vol. 6, no. 2, pp. 276-296 . https://doi.org/10.1002/iid3.216

Introduction: Intracellular reactive oxidant species (ROS) are generated in human airway epithelial cells by the prothrombinase action of Group 1 house dust mite (HDM) allergens and by ligation of viral RNA sensor Toll-like receptors (TLRs). We explo

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